Preclinical and clinical perfusion MRI

Research Works

The CVS team develops non-contrast myocardial perfusion MRI techniques for both human and small animal applications. Several original arterial spin labeling MRI methods such as steady-pulsed ASL (spASL) (Capron Magn. Reson. Med 2013) and cineASL (Troalen Magn. Reson. Med 2012) were invented.

Cine-ASL allows fast quantitative and time-resolved mapping of rat and mouse myocardial perfusion throughout the cardiac cycle. spASL and cineASL are under continued development.

GUI post-processing tools were developed for easy visualization and quantification of ASL Myocardial Blood Flow data coming from clinical and preclinical scanners. They are used by the team for its application studies. MRI sequences and Python/Qt-based tools are also made available to others on demand.

Perfusion map in a healthy volunteer using ASL.

List of fundings::

QASAREM – ANR BLAN 2008 – 2012
COFLORES – ANR TechSan 2014 – 2018
COFLORES – FRM 2015 – 2018

Related: We participate in
BRAVEHEART – FLI RE2 2022 – 2023

Member List:

Frank Kober (Research Director, CNRS)

Associated Keywords

  • Heart
  • Heart Failure
  • Image Processing
  • Microcirculation
  • MR Physics / MR Method developments
  • Perfusion Imaging (Arterial Spin Labeling)
  • Perfusion Methods

Projects