MRI of Blood Brain Barrier Disruption
Research Works
Principal investigators : Angèle Viola, Adriana Perles-Barbacaru
Members
Anthony Tessier, PhD student
Isabelle Varlet
Emilien Royer
Research
A hyperpermeable blood brain barrier is a marker of inflammation. Hyperpermeability of the blood brain barrier can also be induced pharmacologically or physically. This project concerns the development and the validation of a dynamic MRI technique for the detection of blood brain barrier disruption and the quantification of the Gd-DOTA uptake in brain tissue.
Associated Keywords
- Blood Brain Barrier
- Glymphatic system
- Hyperosmolar solutions
- ICP mass spectrometry
- Vascular endothelium
VIOLA Angèle —