Levy-Rosetti Simon

Spinal cord compressions, such as those observed in traumatic injury or when intervertebral discs degenerate, impair tissue microperfusion. Consequently, tissue (axons, neurons, metabolism, etc.) deteriorate and symptoms (pain, weakness, paralysis, etc.) appear. A major and very invasive surgery is then necessary to decompress spinal cord.
My project aims at developing an MRI-based technique to quantify spinal cord microperfusion within human using ultra-high field MRI (7T) available at CRMBM. This would help detect tissue miroperfusion loss earlier. On the other hand, at LBA, I investigate such spinal cord compressions through Finite Element Modeling simulations using the Spine Model for Safety and Surgery (SM2S) developed within the iLab-Spine, international associate laboratory between Marseille (France) and Montreal (Canada). The final goal is to relate microperfusion maps to simulated constraint and stress maps within Cervical Spondylothic Myelopathy (CSM) patients.