180164
1
apa
50
default
718
https://crmbm.univ-amu.fr/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A1750%2C%22request_next%22%3A50%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%223984D4ID%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kober%20et%20al.%22%2C%22parsedDate%22%3A%222002-12-27%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BKober%2C%20F.%2C%20Caus%2C%20T.%2C%20Riberi%2C%20A.%2C%20Confort-Gouny%2C%20S.%2C%20LeFur%2C%20Y.%2C%20Izquierdo%2C%20M.%2C%20Ranjeva%2C%20J.-P.%2C%20Viout%2C%20P.%2C%20Mesana%2C%20T.%2C%20Metras%2C%20D.%2C%20Cozzone%2C%20P.%20J.%2C%20%26amp%3B%20Bernard%2C%20M.%20%282002%29.%20Objective%20and%20noninvasive%20metabolic%20characterization%20of%20donor%20hearts%20by%20phosphorous-31%20magnetic%20resonance%20spectroscopy.%20%26lt%3Bi%26gt%3BTransplantation%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B74%26lt%3B%5C%2Fi%26gt%3B%2812%29%2C%201752%26%23x2013%3B1756.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2F00007890-200212270-00018%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2F00007890-200212270-00018%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Objective%20and%20noninvasive%20metabolic%20characterization%20of%20donor%20hearts%20by%20phosphorous-31%20magnetic%20resonance%20spectroscopy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frank%22%2C%22lastName%22%3A%22Kober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thierry%22%2C%22lastName%22%3A%22Caus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alberto%22%2C%22lastName%22%3A%22Riberi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylviane%22%2C%22lastName%22%3A%22Confort-Gouny%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yann%22%2C%22lastName%22%3A%22LeFur%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marguerite%22%2C%22lastName%22%3A%22Izquierdo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Philippe%22%2C%22lastName%22%3A%22Ranjeva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrick%22%2C%22lastName%22%3A%22Viout%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thierry%22%2C%22lastName%22%3A%22Mesana%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominique%22%2C%22lastName%22%3A%22Metras%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrick%20J.%22%2C%22lastName%22%3A%22Cozzone%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Monique%22%2C%22lastName%22%3A%22Bernard%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20The%20authors%20performed%20a%20multi-institutional%2C%20prospective%2C%20blind%20study%20on%20hearts%20from%20local%20donors%20to%20validate%20the%20feasibility%20and%20accuracy%20of%20the%20metabolic%20evaluation%20of%20human%20hearts%20by%20phosphorus-31%20%28%20P%29%20magnetic%20resonance%20spectroscopy%20%28MRS%29%20before%20transplantation.%5CnMETHODS%3A%20Twenty-one%20hearts%20were%20separated%20into%20two%20groups%20according%20to%20a%20transplantation%20score%20%28TS%29%20on%20the%20basis%20of%20the%20current%20clinical%20and%20echocardiographic%20evaluation%20as%20follows%3A%20TS1%20%28n%3D7%29%2C%20grafts%20for%20United%20Network%20for%20Organ%20Sharing%20%28UNOS%29%201%20patients%20only%3B%20and%20TS2%20%28n%3D14%29%2C%20grafts%20suitable%20for%20UNOS%202%20patients.%20All%20hearts%20were%20cold%20preserved%20with%20Celsior%20and%20underwent%20ex%20situ%20P%20MRS%20to%20measure%20ratios%20of%20various%20high-energy%20phosphate%20metabolites%20and%20the%20intracellular%20pH%20%28pHi%29.%5CnRESULTS%3A%20The%20total%20duration%20of%20the%20MRS%20procedure%20was%2032%20min%2C%20thereby%20not%20unacceptably%20increasing%20the%20total%20ischemic%20time%20for%20the%20transplanted%20grafts.%20Phosphocreatine%20%28PCr%29%20and%20inorganic%20phosphate%20%28Pi%20%29%20was%20significantly%20different%20between%20the%20two%20groups%20%280.95%2B%5C%2F-0.29%20for%20TS1%20and%202.05%2B%5C%2F-0.74%20for%20TS2%29.%20The%20difference%20in%20pHi%20was%20also%20significant%20%287.44%2B%5C%2F-0.13%20for%20TS1%20and%207.64%2B%5C%2F-0.19%20for%20TS2%29.%5CnCONCLUSIONS%3A%20Determination%20of%20PCr-Pi%20and%20pHi%20as%20markers%20of%20ischemic%20injury%20before%20transplantation%20can%20be%20considered%20as%20an%20objective%20and%20accurate%20criterion%20for%20the%20decision%20to%20accept%20or%20refuse%20heart%20grafts%20for%20transplantation.%22%2C%22date%22%3A%22Dec%2027%2C%202002%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2F00007890-200212270-00018%22%2C%22ISSN%22%3A%220041-1337%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22SVI8UJ6H%22%2C%227JR7EDKF%22%2C%225Z6CVJGB%22%2C%22QU2QXBVV%22%2C%22UP3H3ICX%22%2C%224ZGX55W3%22%2C%22BR9D2SS4%22%5D%2C%22dateModified%22%3A%222025-10-06T13%3A32%3A07Z%22%7D%7D%2C%7B%22key%22%3A%222EDLR7UJ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Melka%20et%20al.%22%2C%22parsedDate%22%3A%222025-09-19%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMelka%2C%20M.%2C%20Rotard%2C%20L.%2C%20Benstaali%2C%20C.%2C%20Brocard%2C%20J.%2C%20Giannesini%2C%20B.%2C%20Jouve%2C%20F.%2C%20Pelletier%2C%20L.%2C%20Faur%26%23xE9%3B%2C%20J.%2C%20Rendu%2C%20J.%2C%20Jacquemond%2C%20V.%2C%20%26amp%3B%20Marty%2C%20I.%20%282025%29.%20Limited%20pre-clinical%20relevance%20of%20the%20heterozygous%20RYR1-I4895T%5C%2F%2B%20mouse%20model%20due%20to%20its%20mild%20phenotype.%20%26lt%3Bi%26gt%3BJournal%20of%20Neuromuscular%20Diseases%26lt%3B%5C%2Fi%26gt%3B%2C%2022143602251339354.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F22143602251339354%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F22143602251339354%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Limited%20pre-clinical%20relevance%20of%20the%20heterozygous%20RYR1-I4895T%5C%2F%2B%20mouse%20model%20due%20to%20its%20mild%20phenotype%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Margaux%22%2C%22lastName%22%3A%22Melka%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ludivine%22%2C%22lastName%22%3A%22Rotard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Benstaali%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julie%22%2C%22lastName%22%3A%22Brocard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Giannesini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fanny%22%2C%22lastName%22%3A%22Jouve%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laurent%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julien%22%2C%22lastName%22%3A%22Faur%5Cu00e9%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%22%2C%22lastName%22%3A%22Rendu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%22%2C%22lastName%22%3A%22Jacquemond%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabelle%22%2C%22lastName%22%3A%22Marty%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Although%20genetically-engineered%20mouse%20models%20are%20revolutionizing%20our%20understanding%20of%20numerous%20human%20diseases%2C%20some%20of%20them%20fail%20to%20reproduce%20or%20to%20mimic%20the%20human%20condition%20or%20even%20exhibit%20distinct%20disease%20features%20depending%20on%20the%20mouse%20genetic%20background%2C%20on%20the%20environment%20conditions%2C%20and%5C%2For%20on%20unknown%20parameters.%5CnOBJECTIVE%3A%20Experiments%20aimed%20at%20further%20characterizing%20the%20muscle%20defects%20associated%20with%20the%20I-T%20substitution%20at%20position%204898%20of%20the%20human%20type%201%20ryanodine%20receptor%20%28RyR1%29%20protein%20sequence%2C%20responsible%20for%20central%20core%20disease%20in%20affected%20patients%2C%20to%20use%20this%20model%20for%20therapeutic%20development.%20RyR1%20is%20a%20cationic%20channel%20in%20the%20sarcoplasmic%20reticulum%20membrane%20that%20is%20responsible%20for%20the%20Ca2%2B%20release%20flux%20that%20triggers%20muscle%20contraction.%20The%20above%20I-T%20change%20was%20previously%20described%20to%20alter%20RyR1%20channel%20permeation%20so%20as%20to%20produce%20muscle%20weakness.%5CnMETHODS%3A%20We%20used%20the%20corresponding%20I4895T%20mouse%20model%2C%20previously%20shown%20unviable%20in%20the%20homozygous%20form%2C%20and%20with%20heterozygous%20animals%20suffering%20from%20depressed%20RyR1-mediated%20Ca2%2B%20flux%20and%20muscle%20force%20production.%20We%20performed%20a%20full%20characterization%2C%20at%20the%20molecular%20level%20of%20the%20RYR1%20gene%20and%20transcript%2C%20and%20at%20the%20functional%20level%20at%20the%20isolated%20fiber%20or%20whole%20animal%20levels.%5CnRESULTS%3A%20We%20found%20no%20significant%20deficit%20in%20the%20heterozygous%20animals%2C%20from%20force%20and%20activity%20parameters%20at%20the%20whole%20organism%20level%2C%20to%20contraction%20of%20isolated%20muscles%20and%20Ca2%2B%20release%20in%20single%20isolated%20muscle%20fibers.%5CnCONCLUSIONS%3A%20Our%20results%20prompt%20the%20need%20for%20caution%20when%20using%20this%20model%2C%20and%20point%20to%20its%20potential%20limited%20relevance%20for%20preclinical%20studies.%22%2C%22date%22%3A%222025-09-19%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1177%5C%2F22143602251339354%22%2C%22ISSN%22%3A%222214-3602%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%226DHTGFMA%22%5D%2C%22dateModified%22%3A%222025-09-22T07%3A47%3A16Z%22%7D%7D%2C%7B%22key%22%3A%228AHVYGKV%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brun%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBrun%2C%20G.%2C%20Testud%2C%20B.%2C%20Girard%2C%20O.%20M.%2C%20Lehmann%2C%20P.%2C%20de%20Rochefort%2C%20L.%2C%20Besson%2C%20P.%2C%20Massire%2C%20A.%2C%20Ridley%2C%20B.%2C%20Girard%2C%20N.%2C%20Guye%2C%20M.%2C%20Ranjeva%2C%20J.-P.%2C%20%26amp%3B%20Le%20Troter%2C%20A.%20%282022%29.%20Automatic%20segmentation%20of%20deep%20grey%20nuclei%20using%20a%20high-resolution%207T%20magnetic%20resonance%20imaging%20atlas%26%23x2014%3BQuantification%20of%20T1%20values%20in%20healthy%20volunteers.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Neuroscience%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B55%26lt%3B%5C%2Fi%26gt%3B%282%29%2C%20438%26%23x2013%3B460.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fejn.15575%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fejn.15575%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Automatic%20segmentation%20of%20deep%20grey%20nuclei%20using%20a%20high-resolution%207T%20magnetic%20resonance%20imaging%20atlas%5Cu2014Quantification%20of%20T1%20values%20in%20healthy%20volunteers%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gilles%22%2C%22lastName%22%3A%22Brun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olivier%20M.%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Lehmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ludovic%22%2C%22lastName%22%3A%22de%20Rochefort%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Besson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aur%5Cu00e9lien%22%2C%22lastName%22%3A%22Massire%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ben%22%2C%22lastName%22%3A%22Ridley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Philippe%22%2C%22lastName%22%3A%22Ranjeva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Le%20Troter%22%7D%5D%2C%22abstractNote%22%3A%22We%20present%20a%20new%20consensus%20atlas%20of%20deep%20grey%20nuclei%20obtained%20by%20shape-based%20averaging%20of%20manual%20segmentation%20of%20two%20experienced%20neuroradiologists%20and%20optimized%20from%207T%20MP2RAGE%20images%20acquired%20at%20%28.6%20mm%293%20in%2060%20healthy%20subjects.%20A%20group-wise%20normalization%20method%20was%20used%20to%20build%20a%20high-contrast%20and%20high-resolution%20T1-weighted%20brain%20template%20%28.5%20mm%293%20using%20data%20from%2030%20out%20of%20the%2060%20controls.%20Delineation%20of%2024%20deep%20grey%20nuclei%20per%20hemisphere%2C%20including%20the%20claustrum%20and%2012%20thalamic%20nuclei%2C%20was%20then%20performed%20by%20two%20expert%20neuroradiologists%20and%20reviewed%20by%20a%20third%20neuroradiologist%20according%20to%20tissue%20contrast%20and%20external%20references%20based%20on%20the%20Morel%20atlas.%20Corresponding%20deep%20grey%20matter%20structures%20were%20also%20extracted%20from%20the%20Morel%20and%20CIT168%20atlases.%20The%20data-derived%2C%20Morel%20and%20CIT168%20atlases%20were%20all%20applied%20at%20the%20individual%20level%20using%20non-linear%20registration%20to%20fit%20the%20subject%20reference%20and%20to%20extract%20absolute%20mean%20quantitative%20T1%20values%20derived%20from%20the%203D-MP2RAGE%20volumes%2C%20after%20correction%20for%20residual%20B1%2B%20biases.%20Three%20metrics%20%28the%20Dice%20and%20the%20volumetric%20similarity%20coefficients%20and%20a%20novel%20Hausdorff%20distance%29%20were%20used%20to%20estimate%20the%20inter-rater%20agreement%20of%20manual%20MRI%20segmentation%20and%20inter-atlas%20variability%2C%20and%20these%20metrics%20were%20measured%20to%20quantify%20biases%20due%20to%20image%20registration%2C%20and%20their%20impact%20on%20the%20measurements%20of%20the%20quantitative%20T1%20values%20was%20highlighted.%20This%20represents%20a%20fully%20automated%20segmentation%20process%20permitting%20the%20extraction%20of%20unbiased%20normative%20T1%20values%20in%20a%20population%20of%20young%20healthy%20controls%20as%20a%20reference%20for%20characterizing%20subtle%20structural%20alterations%20of%20deep%20grey%20nuclei%20relevant%20to%20a%20range%20of%20neurological%20diseases.%22%2C%22date%22%3A%222022%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fejn.15575%22%2C%22ISSN%22%3A%221460-9568%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fejn.15575%22%2C%22collections%22%3A%5B%2274RX9758%22%2C%22UP3H3ICX%22%2C%22HVJZKIZG%22%2C%22W98NEAUQ%22%2C%22HHEPZHEJ%22%2C%22FK6KXTMZ%22%2C%22DNKN89WD%22%2C%225P5FWCR9%22%2C%22XTA6KS7L%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A46%3A01Z%22%7D%7D%2C%7B%22key%22%3A%22GRXQFTBW%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Haast%20et%20al.%22%2C%22parsedDate%22%3A%222023%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHaast%2C%20R.%20A.%20M.%2C%20Testud%2C%20B.%2C%20Makhalova%2C%20J.%2C%20Dary%2C%20H.%2C%20Cabane%2C%20A.%2C%20Le%20Troter%2C%20A.%2C%20Ranjeva%2C%20J.-P.%2C%20Bartolomei%2C%20F.%2C%20%26amp%3B%20Guye%2C%20M.%20%282023%29.%20Multi-scale%20structural%20alterations%20of%20the%20thalamus%20and%20basal%20ganglia%20in%20focal%20epilepsy%20using%207T%20MRI.%20%26lt%3Bi%26gt%3BHuman%20Brain%20Mapping%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B44%26lt%3B%5C%2Fi%26gt%3B%2813%29%2C%204754%26%23x2013%3B4771.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fhbm.26414%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fhbm.26414%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Multi-scale%20structural%20alterations%20of%20the%20thalamus%20and%20basal%20ganglia%20in%20focal%20epilepsy%20using%207T%20MRI%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roy%20A.%20M.%22%2C%22lastName%22%3A%22Haast%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julia%22%2C%22lastName%22%3A%22Makhalova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hugo%22%2C%22lastName%22%3A%22Dary%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandre%22%2C%22lastName%22%3A%22Cabane%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Le%20Troter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Philippe%22%2C%22lastName%22%3A%22Ranjeva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabrice%22%2C%22lastName%22%3A%22Bartolomei%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%5D%2C%22abstractNote%22%3A%22Focal%20epilepsy%20is%20characterized%20by%20repeated%20spontaneous%20seizures%20that%20originate%20from%20cortical%20epileptogenic%20zone%20networks%20%28EZN%29.%20Analysis%20of%20intracerebral%20recordings%20showed%20that%20subcortical%20structures%2C%20and%20in%20particular%20the%20thalamus%2C%20play%20an%20important%20role%20in%20seizure%20dynamics%20as%20well%2C%20supporting%20their%20structural%20alterations%20reported%20in%20the%20neuroimaging%20literature.%20Nonetheless%2C%20between-patient%20differences%20in%20EZN%20localization%20%28e.g.%2C%20temporal%20vs.%20non-temporal%20lobe%20epilepsy%29%20as%20well%20as%20extension%20%28i.e.%2C%20number%20of%20epileptogenic%20regions%29%20might%20impact%20the%20magnitude%20as%20well%20as%20spatial%20distribution%20of%20subcortical%20structural%20changes.%20Here%20we%20used%207%20Tesla%20MRI%20T1%20data%20to%20provide%20an%20unprecedented%20description%20of%20subcortical%20morphological%20%28volume%2C%20tissue%20deformation%2C%20and%20shape%29%20and%20longitudinal%20relaxation%20%28T1%29%20changes%20in%20focal%20epilepsy%20patients%20and%20evaluate%20the%20impact%20of%20the%20EZN%20and%20other%20patient-specific%20clinical%20features.%20Our%20results%20showed%20variable%20levels%20of%20atrophy%20across%20thalamic%20nuclei%20that%20appeared%20most%20prominent%20in%20the%20temporal%20lobe%20epilepsy%20group%20and%20the%20side%20ipsilateral%20to%20the%20EZN%2C%20while%20shortening%20of%20T1%20was%20especially%20observed%20for%20the%20lateral%20thalamus.%20Multivariate%20analyses%20across%20thalamic%20nuclei%20and%20basal%20ganglia%20showed%20that%20volume%20acted%20as%20the%20dominant%20discriminator%20between%20patients%20and%20controls%2C%20while%20%28posterolateral%29%20thalamic%20T1%20measures%20looked%20promising%20to%20further%20differentiate%20patients%20based%20on%20EZN%20localization.%20In%20particular%2C%20the%20observed%20differences%20in%20T1%20changes%20between%20thalamic%20nuclei%20indicated%20differential%20involvement%20based%20on%20EZN%20localization.%20Finally%2C%20EZN%20extension%20was%20found%20to%20best%20explain%20the%20observed%20variability%20between%20patients.%20To%20conclude%2C%20this%20work%20revealed%20multi-scale%20subcortical%20alterations%20in%20focal%20epilepsy%20as%20well%20as%20their%20dependence%20on%20several%20clinical%20characteristics.%22%2C%22date%22%3A%222023%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fhbm.26414%22%2C%22ISSN%22%3A%221097-0193%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Fhbm.26414%22%2C%22collections%22%3A%5B%22UP3H3ICX%22%2C%225P5FWCR9%22%2C%22XTA6KS7L%22%2C%22FBQIKF54%22%2C%22PCMV2W5C%22%2C%229RMECNPE%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A46%3A00Z%22%7D%7D%2C%7B%22key%22%3A%227DNU7UU2%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Thiery%20et%20al.%22%2C%22parsedDate%22%3A%222023-04-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BThiery%2C%20L.%2C%20Carle%2C%20X.%2C%20Testud%2C%20B.%2C%20Boulouis%2C%20G.%2C%20Habert%2C%20P.%2C%20Tradi%2C%20F.%2C%20Reyre%2C%20A.%2C%20Lehmann%2C%20P.%2C%20Dory-Lautrec%2C%20P.%2C%20Stellmann%2C%20J.-P.%2C%20Girard%2C%20N.%2C%20Brunel%2C%20H.%2C%20%26amp%3B%20Hak%2C%20J.-F.%20%282023%29.%20Distal%20cerebral%20vasospasm%20treatment%20following%20aneurysmal%20subarachnoid%20hemorrhage%20using%20the%20Comaneci%20device%3A%20technical%20feasibility%20and%20single-center%20preliminary%20results.%20%26lt%3Bi%26gt%3BJournal%20of%20NeuroInterventional%20Surgery%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20325%26%23x2013%3B329.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fneurintsurg-2022-018699%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fneurintsurg-2022-018699%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Distal%20cerebral%20vasospasm%20treatment%20following%20aneurysmal%20subarachnoid%20hemorrhage%20using%20the%20Comaneci%20device%3A%20technical%20feasibility%20and%20single-center%20preliminary%20results%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Louis%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xavier%22%2C%22lastName%22%3A%22Carle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gregoire%22%2C%22lastName%22%3A%22Boulouis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Habert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Farouk%22%2C%22lastName%22%3A%22Tradi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anthony%22%2C%22lastName%22%3A%22Reyre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Lehmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philippe%22%2C%22lastName%22%3A%22Dory-Lautrec%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan-Patrick%22%2C%22lastName%22%3A%22Stellmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Herve%22%2C%22lastName%22%3A%22Brunel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Francois%22%2C%22lastName%22%3A%22Hak%22%7D%5D%2C%22abstractNote%22%3A%22Background%20Balloon-assisted%20mechanical%20angioplasty%20for%20cerebral%20vasospasm%20following%20aneurysmal%20subarachnoid%20hemorrhage%20%28aSAH%29%20has%20a%20number%20of%20limitations%2C%20including%20transient%20occlusion%20of%20the%20spastic%20blood%20vessel.%20Comaneci%20is%20an%20FDA-approved%20device%20for%20temporary%20coil%20embolization%20assistance%20which%20has%20recently%20also%20been%20approved%20for%20the%20treatment%20of%20distal%20symptomatic%20refractory%20vasospasm.%20We%20aimed%20to%20report%20the%20feasibility%2C%20efficacy%20and%20safety%20of%20our%20experience%20with%20Comaneci%20angioplasty%20for%20refractory%20distal%20vasospasm%20%28up%20to%20the%20second%20segment%20of%20the%20cerebral%20arteries%29%20following%20aSAH.%5CnMethods%20This%20is%20a%20retrospective%20analysis%20of%20a%20prospective%20series%20of%2018%20patients%20included%20between%20April%202019%20and%20June%202021%20with%20aSAH%20and%20symptomatic%20vasospasm%20refractory%20to%20medical%20therapy%2C%20who%20were%20treated%20using%20Comaneci-17-asssisted%20mechanical%20distal%20angioplasty.%20Immediate%20angiographic%20results%2C%20procedure-related%20complications%2C%20and%20clinical%20outcomes%20were%20assessed.%20Inter-rater%20reliability%20of%20the%20scores%20was%20determined%20using%20the%20intraclass%20correlation%20coefficient.%5CnResults%20Comaneci-assisted%20distal%20angioplasty%20was%20performed%20in%2018%20patients%2C%20corresponding%20to%2031%20target%20arteries.%20All%20distal%20anterior%20segments%20were%20easily%20accessible%20with%20the%20Comaneci-17%20device.%20Vasospasm%20improvement%20after%20Comaneci%20mechanical%20angioplasty%20was%20seen%20in%2022%20distal%20arteries%20%2871%25%29%20%28weighted%20Cohen%5Cu2019s%20kappa%20%28%5Cu03baw%29%200.73%2C%2095%25%20CI%200.69%20to%200.93%29.%20Vasospasm%20recurrence%20occurred%20in%20three%20patients%20%2816.67%25%29%20and%20delayed%20cerebral%20infarction%20in%20three%20patients%20%2816.67%25%29%2C%20with%20a%20mean%5Cu00b1SD%20delay%20between%20onset%20of%20symptoms%20and%20imaging%20follow-up%20%28MRI%5C%2FCT%29%20of%2032.61%5Cu00b18.93%20days%20%28%5Cu03baw%200.98%2C%2095%25%20CI%200.88%20to%201%29.%5CnConclusion%20This%20initial%20experience%20suggests%20that%20distal%20mechanical%20angioplasty%20performed%20with%20the%20Comaneci-17%20device%20for%20refractory%20vasospasm%20following%20aSAH%20seems%20to%20be%20safe%2C%20with%20good%20feasibility%20and%20efficacy.%22%2C%22date%22%3A%222023%5C%2F04%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1136%5C%2Fneurintsurg-2022-018699%22%2C%22ISSN%22%3A%221759-8478%2C%201759-8486%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjnis.bmj.com%5C%2Fcontent%5C%2F15%5C%2F4%5C%2F325%22%2C%22collections%22%3A%5B%229L2KHJ5X%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A59Z%22%7D%7D%2C%7B%22key%22%3A%22G5IRZU4W%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222021-08-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Brun%2C%20G.%2C%20Varoquaux%2C%20A.%2C%20Hak%2C%20J.%20F.%2C%20Appay%2C%20R.%2C%20Le%20Troter%2C%20A.%2C%20Girard%2C%20N.%2C%20%26amp%3B%20Stellmann%2C%20J.%20P.%20%282021%29.%20Perfusion-weighted%20techniques%20in%20MRI%20grading%20of%20pediatric%20cerebral%20tumors%3A%20efficiency%20of%20dynamic%20susceptibility%20contrast%20and%20arterial%20spin%20labeling.%20%26lt%3Bi%26gt%3BNeuroradiology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B63%26lt%3B%5C%2Fi%26gt%3B%288%29%2C%201353%26%23x2013%3B1366.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00234-021-02640-y%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00234-021-02640-y%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Perfusion-weighted%20techniques%20in%20MRI%20grading%20of%20pediatric%20cerebral%20tumors%3A%20efficiency%20of%20dynamic%20susceptibility%20contrast%20and%20arterial%20spin%20labeling%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Brun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Varoquaux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20F.%22%2C%22lastName%22%3A%22Hak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Appay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Le%20Troter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20P.%22%2C%22lastName%22%3A%22Stellmann%22%7D%5D%2C%22abstractNote%22%3A%22Dynamic%20susceptibility%20contrast%20%28DSC%29%20and%20arterial%20spin%20labeling%20%28ASL%29%20perfusion%20MRI%20are%20applied%20in%20pediatric%20brain%20tumor%20grading%2C%20but%20their%20value%20for%20clinical%20daily%20practice%20remains%20unclear.%20We%20explored%20the%20ability%20of%20ASL%20and%20DSC%20to%20distinguish%20low-%20and%20high-grade%20lesions%2C%20in%20an%20unselected%20cohort%20of%20pediatric%20cerebral%20tumors.%22%2C%22date%22%3A%222021-08-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00234-021-02640-y%22%2C%22ISSN%22%3A%221432-1920%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00234-021-02640-y%22%2C%22collections%22%3A%5B%22W98NEAUQ%22%2C%225P5FWCR9%22%2C%229L2KHJ5X%22%2C%22KBIRKXGV%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22HL5B8A5J%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222023-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Fabiani%2C%20N.%2C%20Demorti%26%23xE8%3Bre%2C%20S.%2C%20Mchinda%2C%20S.%2C%20Medina%2C%20N.%20L.%2C%20Pelletier%2C%20J.%2C%20Guye%2C%20M.%2C%20Audoin%2C%20B.%2C%20Stellmann%2C%20J.%20P.%2C%20%26amp%3B%20Callot%2C%20V.%20%282023%29.%20Contribution%20of%20the%20MP2RAGE%207T%20Sequence%20in%20MS%20Lesions%20of%20the%20Cervical%20Spinal%20Cord.%20%26lt%3Bi%26gt%3BAJNR.%20American%20Journal%20of%20Neuroradiology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B44%26lt%3B%5C%2Fi%26gt%3B%289%29%2C%201101%26%23x2013%3B1107.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3174%5C%2Fajnr.A7964%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3174%5C%2Fajnr.A7964%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Contribution%20of%20the%20MP2RAGE%207T%20Sequence%20in%20MS%20Lesions%20of%20the%20Cervical%20Spinal%20Cord%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Fabiani%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Demorti%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Mchinda%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%20L.%22%2C%22lastName%22%3A%22Medina%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Audoin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20P.%22%2C%22lastName%22%3A%22Stellmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22V.%22%2C%22lastName%22%3A%22Callot%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%20AND%20PURPOSE%3A%20The%20detection%20of%20spinal%20cord%20lesions%20in%20patients%20with%20MS%20is%20challenging.%20Recently%2C%20the%203D%20MP2RAGE%20sequence%20demonstrated%20its%20usefulness%20at%203T.%20Benefiting%20from%20the%20high%20spatial%20resolution%20provided%20by%20ultra-high-field%20MR%20imaging%20systems%2C%20we%20aimed%20to%20evaluate%20the%20contribution%20of%20the%203D%20MP2RAGE%20sequence%20acquired%20at%207T%20for%20the%20detection%20of%20MS%20lesions%20in%20the%20cervical%20spine.%5CnMATERIALS%20AND%20METHODS%3A%20Seventeen%20patients%20with%20MS%20participated%20in%20this%20study.%20They%20were%20examined%20at%20both%203T%20and%207T.%20The%20MR%20imaging%20examination%20included%20a%20Magnetic%20Imaging%20in%20MS%20%28MAGNIMS%29%20protocol%20with%20an%20axial%20T2%2A-WI%20gradient%20recalled-echo%20sequence%20%28%26quot%3Boptimized%20MAGNIMS%20protocol%26quot%3B%29%20and%20a%200.9-mm%20isotropic%203D%20MP2RAGE%20sequence%20at%203T%2C%20as%20well%20as%20a%200.7-mm%20isotropic%20and%200.3-mm%20in-plane-resolution%20anisotropic%203D%20MP2RAGE%20sequences%20at%207T.%20Each%20data%20set%20was%20read%20by%20a%20consensus%20of%20radiologists%2C%20neurologists%2C%20and%20neuroscientists.%20The%20number%20of%20lesions%20and%20their%20topography%2C%20as%20well%20as%20the%20visibility%20of%20the%20lesions%20from%20one%20set%20to%20another%2C%20were%20carefully%20analyzed.%5CnRESULTS%3A%20A%20total%20of%2055%20lesions%20were%20detected.%20The%20absolute%20number%20of%20visible%20lesions%20differed%20among%20the%204%20sequences%20%28linear%20mixed%20effect%20ANOVA%2C%20P%20%3D%20.020%29.%20The%20highest%20detection%20was%20observed%20for%20the%20two%207T%20sequences%20with%2051%20lesions%20each%20%2892.7%25%20of%20the%20total%29.%20The%20optimized%203T%20MAGNIMS%20protocol%20and%20the%203T%20MP2RAGE%20isotropic%20sequence%20detected%2041%20%2874.5%25%29%20and%2035%20lesions%20%2863.6%25%29%2C%20respectively.%5CnCONCLUSIONS%3A%20The%207T%20MP2RAGE%20sequences%20detected%20more%20lesions%20than%20the%203T%20sets.%20Isotropic%20and%20anisotropic%20acquisitions%20performed%20comparably.%20Ultra-high-resolution%20sequences%20obtained%20at%207T%20improve%20the%20identification%20and%20delineation%20of%20lesions%20of%20the%20cervical%20spinal%20cord%20in%20MS.%22%2C%22date%22%3A%222023-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3174%5C%2Fajnr.A7964%22%2C%22ISSN%22%3A%221936-959X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22ZFC2Q648%22%2C%22B4EWFM7E%22%2C%226KPLZTET%22%2C%229L2KHJ5X%22%2C%22XTA6KS7L%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A57Z%22%7D%7D%2C%7B%22key%22%3A%2238E4KEIZ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222022-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Stellmann%2C%20J.-P.%2C%20Girard%2C%20N.%2C%20%26amp%3B%20Hak%2C%20J.-F.%20%282022%29.%20Tumoral%20Hemorrhagic%20Stroke%20Revealing%20Carotid%20Angiosarcoma-Related%20Cerebral%20Metastases.%20%26lt%3Bi%26gt%3BNeurology%20India%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B70%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%202246%26%23x2013%3B2248.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.4103%5C%2F0028-3886.359227%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.4103%5C%2F0028-3886.359227%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Tumoral%20Hemorrhagic%20Stroke%20Revealing%20Carotid%20Angiosarcoma-Related%20Cerebral%20Metastases%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan-Patrick%22%2C%22lastName%22%3A%22Stellmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Francois%22%2C%22lastName%22%3A%22Hak%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222022%20Sep-Oct%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.4103%5C%2F0028-3886.359227%22%2C%22ISSN%22%3A%221998-4022%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22W98NEAUQ%22%2C%229L2KHJ5X%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A57Z%22%7D%7D%2C%7B%22key%22%3A%22D8SUN8YT%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Brun%2C%20G.%2C%20Kaphan%2C%20E.%2C%20Stellmann%2C%20J.%20P.%2C%20Girard%2C%20N.%2C%20%26amp%3B%20Hak%2C%20J.-F.%20%282021%29.%20Distinctive%20MRI%20features%20of%20paraneoplastic%20encephalitis%20with%20anti-Ri%20antibodies.%20%26lt%3Bi%26gt%3BRevue%20Neurologique%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B177%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20315%26%23x2013%3B317.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2020.05.009%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2020.05.009%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Distinctive%20MRI%20features%20of%20paraneoplastic%20encephalitis%20with%20anti-Ri%20antibodies%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Brun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Kaphan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.P.%22%2C%22lastName%22%3A%22Stellmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.-F.%22%2C%22lastName%22%3A%22Hak%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2203%5C%2F2021%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.neurol.2020.05.009%22%2C%22ISSN%22%3A%2200353787%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS0035378720306196%22%2C%22collections%22%3A%5B%22W98NEAUQ%22%2C%229L2KHJ5X%22%2C%22NLCL528K%22%2C%22X9AF3XQR%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A56Z%22%7D%7D%2C%7B%22key%22%3A%22JLHSNQQX%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Delacour%2C%20C.%2C%20El%20Ahmadi%2C%20A.%20A.%2C%20Brun%2C%20G.%2C%20Girard%2C%20N.%2C%20Duhamel%2C%20G.%2C%20Heesen%2C%20C.%2C%20H%26%23xE4%3Bu%26%23xDF%3Bler%2C%20V.%2C%20Thaler%2C%20C.%2C%20Has%20Silemek%2C%20A.%20C.%2C%20%26amp%3B%20Stellmann%2C%20J.-P.%20%282022%29.%20Brain%20grey%20matter%20perfusion%20in%20primary%20progressive%20multiple%20sclerosis%3A%20Mild%20decrease%20over%20years%20and%20regional%20associations%20with%20cognition%20and%20hand%20function.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Neurology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B29%26lt%3B%5C%2Fi%26gt%3B%286%29%2C%201741%26%23x2013%3B1752.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fene.15289%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fene.15289%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Brain%20grey%20matter%20perfusion%20in%20primary%20progressive%20multiple%20sclerosis%3A%20Mild%20decrease%20over%20years%20and%20regional%20associations%20with%20cognition%20and%20hand%20function%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clara%22%2C%22lastName%22%3A%22Delacour%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ahmed%20Ali%22%2C%22lastName%22%3A%22El%20Ahmadi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gilles%22%2C%22lastName%22%3A%22Brun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Guillaume%22%2C%22lastName%22%3A%22Duhamel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Heesen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vivien%22%2C%22lastName%22%3A%22H%5Cu00e4u%5Cu00dfler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Thaler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arzu%20Ceylan%22%2C%22lastName%22%3A%22Has%20Silemek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan-Patrick%22%2C%22lastName%22%3A%22Stellmann%22%7D%5D%2C%22abstractNote%22%3A%22Background%20and%20purpose%20Extent%20and%20dynamic%20of%20neurodegeneration%20in%20progressive%20multiple%20sclerosis%20%28MS%29%20might%20be%20reflected%20by%20global%20and%20regional%20brain%20perfusion%2C%20an%20outcome%20at%20the%20intercept%20between%20structure%20and%20function.%20Here%2C%20we%20provide%20a%20first%20insight%20into%20the%20evolution%20of%20brain%20perfusion%20and%20its%20association%20with%20disability%20in%20primary%20progressive%20MS%20%28PPMS%29%20over%20several%20years.%20Methods%20Seventy-seven%20persons%20with%20PPMS%20were%20followed%20over%20up%20to%205%20years.%20Visits%20included%20a%203-T%20magnetic%20resonance%20imaging%20with%20pulsed%20arterial%20spin%20labelling%20perfusion%2C%20the%20Timed%2025-Foot%20Walk%2C%209-Hole%20Peg%20Test%20%28NHPT%29%2C%20Symbol%20Digit%20Modalities%20Test%20%28SDMT%29%2C%20and%20Expanded%20Disability%20Status%20Scale%20%28EDSS%29.%20We%20extracted%20regional%20cerebral%20blood%20flow%20surrogates%20and%20compared%20them%20to%2011%20controls.%20Analyses%20focused%20on%20cortical%20and%20deep%20grey%20matter%2C%20the%20change%20over%20time%2C%20and%20associations%20with%20disability%20on%20the%20regional%20and%20global%20levels.%20Results%20Baseline%20brain%20perfusion%20of%20patients%20and%20controls%20was%20comparable%20for%20the%20cortex%20%28p%20%3D%200.716%29%20and%20deep%20grey%20matter%20%28p%20%3D%200.095%29.%20EDSS%20disability%20increased%20mildly%20%28p%20%3D%200.023%29%2C%20whereas%20brain%20perfusion%20decreased%20during%20follow-up%20%28p%20%26lt%3B%200.001%29%20and%20with%20disease%20duration%20%28p%20%3D%200.009%29.%20Lower%20global%20perfusion%20correlated%20with%20higher%20disability%20as%20indicated%20by%20EDSS%2C%20NHPT%2C%20and%20Timed%2025-Foot%20Walk%20%28p%20%26lt%3B%200.001%29.%20The%20motor%20task%20NHPT%20showed%20associations%20with%2020%20grey%20matter%20regions.%20In%20contrast%2C%20better%20SDMT%20performance%20correlated%20with%20lower%20perfusion%20%28p%20%26lt%3B%200.001%29%20in%20seven%20predominantly%20frontal%20regions%2C%20indicating%20a%20functional%20maladaptation.%20Conclusions%20Decreasing%20perfusion%20indicates%20a%20putative%20association%20with%20MS%20disease%20mechanisms%20such%20as%20neurodegeneration%2C%20reduced%20metabolism%2C%20and%20loss%20of%20resilience.%20A%20low%20alteration%20rate%20limits%20its%20use%20in%20clinical%20practice%2C%20but%20regional%20association%20patterns%20might%20provide%20a%20snapshot%20of%20adaptive%20and%20maladaptive%20functional%20reorganization.%22%2C%22date%22%3A%222022%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fene.15289%22%2C%22ISSN%22%3A%221468-1331%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fene.15289%22%2C%22collections%22%3A%5B%224U7D3E9U%22%2C%22W98NEAUQ%22%2C%229L2KHJ5X%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22FT2GJW9H%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Drai%20et%20al.%22%2C%22parsedDate%22%3A%222022-06%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDrai%2C%20M.%2C%20Testud%2C%20B.%2C%20Brun%2C%20G.%2C%20Hak%2C%20J.-F.%2C%20Scavarda%2C%20D.%2C%20Girard%2C%20N.%2C%20%26amp%3B%20Stellmann%2C%20J.-P.%20%282022%29.%20Borrowing%20strength%20from%20adults%3A%20Transferability%20of%20AI%20algorithms%20for%20paediatric%20brain%20and%20tumour%20segmentation.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Radiology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B151%26lt%3B%5C%2Fi%26gt%3B%2C%20110291.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ejrad.2022.110291%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ejrad.2022.110291%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Borrowing%20strength%20from%20adults%3A%20Transferability%20of%20AI%20algorithms%20for%20paediatric%20brain%20and%20tumour%20segmentation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Drai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gilles%22%2C%22lastName%22%3A%22Brun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Fran%5Cu00e7ois%22%2C%22lastName%22%3A%22Hak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Didier%22%2C%22lastName%22%3A%22Scavarda%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan-Patrick%22%2C%22lastName%22%3A%22Stellmann%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20AI%20brain%20tumour%20segmentation%20and%20brain%20extraction%20algorithms%20promise%20better%20diagnostic%20and%20follow-up%20of%20brain%20tumours%20in%20adults.%20The%20development%20of%20such%20tools%20for%20paediatric%20populations%20is%20restricted%20by%20limited%20training%20data%20but%20careful%20adaption%20of%20adult%20algorithms%20to%20paediatric%20population%20might%20be%20a%20solution.%20Here%2C%20we%20aim%20exploring%20the%20transferability%20of%20algorithms%20for%20brain%20%28HD-BET%29%20and%20tumour%20segmentation%20%28HD-GLIOMA%29%20in%20adults%20to%20paediatric%20imaging%20studies.%5CnMETHOD%3A%20In%20a%20retrospective%20cohort%2C%20we%20compared%20automated%20segmentation%20with%20expert%20masks.%20We%20used%20the%20dice%20coefficient%20for%20evaluating%20the%20similarity%20and%20multivariate%20regressions%20for%20the%20influence%20of%20covariates.%20We%20explored%20the%20feasibility%20of%20automatic%20tumor%20classification%20based%20on%20diffusion%20data.%5CnRESULTS%3A%20In%2042%20patients%20%28mean%20age%207%5Cu00a0years%2C%209%20below%202%5Cu00a0years%2C%2026%20males%29%2C%20segmentation%20was%20excellent%20for%20brain%20extraction%20%28mean%20dice%200.99%2C%20range%200.85-1%29%2C%20moderate%20for%20segmentation%20of%20contrast-enhancing%20tumours%20%28mean%20dice%200.67%2C%20range%200-1%29%2C%20and%20weak%20for%20non-enhancing%20T2-signal%20abnormalities%20%28mean%20dice%200.41%29.%20Precision%20was%20better%20for%20enhancing%20tumour%20parts%20%28p%5Cu00a0%26lt%3B%5Cu00a00.001%29%20and%20for%20malignant%20histology%20%28p%5Cu00a0%3D%5Cu00a00.006%20and%20p%5Cu00a0%3D%5Cu00a00.012%29%20but%20independent%20from%20myelinisation%20as%20indicated%20by%20the%20age%20%28p%5Cu00a0%3D%5Cu00a00.472%29.%20Automated%20tumour%20grading%20based%20on%20mean%20diffusivity%20%28MD%29%20values%20from%20automated%20masks%20was%20good%20%28AUC%5Cu00a0%3D%5Cu00a00.86%29%20but%20tended%20to%20be%20less%20accurate%20than%20MD%20values%20from%20expert%20masks%20%28AUC%5Cu00a0%3D%5Cu00a01%2C%20p%5Cu00a0%3D%5Cu00a00.208%29.%5CnCONCLUSION%3A%20HD-BET%20provides%20a%20reliable%20extraction%20of%20the%20paediatric%20brain.%20HD-GLIOMA%20works%20moderately%20for%20contrast-enhancing%20tumours%20parts.%20Without%20optimization%2C%20brain%20tumor%20AI%20algorithms%20trained%20on%20adults%20and%20used%20on%20paediatric%20patients%20may%20yield%20acceptable%20results%20depending%20on%20the%20clinical%20scenario.%22%2C%22date%22%3A%222022-06%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ejrad.2022.110291%22%2C%22ISSN%22%3A%221872-7727%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22W98NEAUQ%22%2C%229L2KHJ5X%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22GFN8IANH%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Tilsley%20et%20al.%22%2C%22parsedDate%22%3A%222024-04-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTilsley%2C%20P.%2C%20Moutiez%2C%20A.%2C%20Brodovitch%2C%20A.%2C%20Mendili%2C%20M.%20M.%20E.%2C%20Testud%2C%20B.%2C%20Zaaraoui%2C%20W.%2C%20Verschueren%2C%20A.%2C%20Attarian%2C%20S.%2C%20Guye%2C%20M.%2C%20Boucraut%2C%20J.%2C%20Grapperon%2C%20A.-M.%2C%20%26amp%3B%20Stellmann%2C%20J.-P.%20%282024%29.%20Neurofilament%20Light%20Chain%20Levels%20Interact%20with%20Neurodegenerative%20Patterns%20and%20Motor%20Neuron%20Dysfunction%20in%20Amyotrophic%20Lateral%20Sclerosis.%20%26lt%3Bi%26gt%3BAmerican%20Journal%20of%20Neuroradiology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B45%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20494%26%23x2013%3B503.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3174%5C%2Fajnr.A8154%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3174%5C%2Fajnr.A8154%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Neurofilament%20Light%20Chain%20Levels%20Interact%20with%20Neurodegenerative%20Patterns%20and%20Motor%20Neuron%20Dysfunction%20in%20Amyotrophic%20Lateral%20Sclerosis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Penelope%22%2C%22lastName%22%3A%22Tilsley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antoine%22%2C%22lastName%22%3A%22Moutiez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandre%22%2C%22lastName%22%3A%22Brodovitch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mohamed%20Mounir%20El%22%2C%22lastName%22%3A%22Mendili%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wafaa%22%2C%22lastName%22%3A%22Zaaraoui%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annie%22%2C%22lastName%22%3A%22Verschueren%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shahram%22%2C%22lastName%22%3A%22Attarian%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jos%5Cu00e9%22%2C%22lastName%22%3A%22Boucraut%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aude-Marie%22%2C%22lastName%22%3A%22Grapperon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan-Patrick%22%2C%22lastName%22%3A%22Stellmann%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%20AND%20PURPOSE%3A%20Amyotrophic%20lateral%20sclerosis%20%28ALS%29%20is%20a%20neurodegenerative%20disease%20involving%20rapid%20motor%20neuron%20degeneration%20leading%20to%20brain%2C%20primarily%20precentral%2C%20atrophy.%20Neurofilament%20light%20chains%20are%20a%20robust%20prognostic%20biomarker%20highly%20specific%20to%20ALS%2C%20yet%20associations%20between%20neurofilament%20light%20chains%20and%20MR%20imaging%20outcomes%20are%20not%20well-understood.%20We%20investigated%20the%20role%20of%20neurofilament%20light%20chains%20as%20mediators%20among%20neuroradiologic%20assessments%2C%20precentral%20neurodegeneration%2C%20and%20disability%20in%20ALS.%5CnMATERIALS%20AND%20METHODS%3A%20We%20retrospectively%20analyzed%20a%20prospective%20cohort%20of%2029%20patients%20with%20ALS%20%28mean%20age%2C%2056%20%5BSD%2C%2012%5D%20years%3B%2018%20men%29%20and%2036%20controls%20%28mean%20age%2C%2049%20%5BSD%2C%2011%5D%20years%3B%2018%20men%29.%20Patients%20underwent%203T%20%28n%20%3D%2019%29%20or%207T%20%28n%20%3D%2010%29%20MR%20imaging%2C%20serum%20%28n%20%3D%2023%29%20and%20CSF%20%28n%20%3D%2015%29%20neurofilament%20light%20chains%2C%20and%20clinical%20%28n%20%3D%2029%29%20and%20electrophysiologic%20%28n%20%3D%2027%29%20assessments.%20The%20control%20group%20had%20equivalent%203T%20%28n%20%3D%2025%29%20or%207T%20%28n%20%3D%2011%29%20MR%20imaging.%20Two%20trained%20neuroradiologists%20performed%20blinded%20qualitative%20assessments%20of%20MR%20imaging%20anomalies%20%28n%20%3D%2029%20patients%2C%20n%20%3D%2036%20controls%29.%20Associations%20between%20precentral%20cortical%20thickness%20and%20neurofilament%20light%20chains%20and%20clinical%20and%20electrophysiologic%20data%20were%20analyzed.%5CnRESULTS%3A%20We%20observed%20extensive%20cortical%20thinning%20in%20patients%20compared%20with%20controls.%20MR%20imaging%20analyses%20showed%20significant%20associations%20between%20precentral%20cortical%20thickness%20and%20bulbar%20or%20arm%20impairment%20following%20distributions%20corresponding%20to%20the%20motor%20homunculus.%20Finally%2C%20uncorrected%20results%20showed%20positive%20interactions%20among%20precentral%20cortical%20thickness%2C%20serum%20neurofilament%20light%20chains%2C%20and%20electrophysiologic%20outcomes.%20Qualitative%20MR%20imaging%20anomalies%20including%20global%20atrophy%20%28P%20%3D%20.003%29%20and%20FLAIR%20corticospinal%20tract%20hypersignal%20anomalies%20%28P%20%3D%20.033%29%2C%20correlated%20positively%20with%20serum%20neurofilament%20light%20chains.%5CnCONCLUSIONS%3A%20Serum%20neurofilament%20light%20chains%20may%20be%20an%20important%20mediator%20between%20clinical%20symptoms%20and%20neuronal%20loss%20according%20to%20cortical%20thickness.%20Furthermore%2C%20MR%20imaging%20anomalies%20might%20have%20underestimated%20prognostic%20value%20because%20they%20seem%20to%20indicate%20higher%20serum%20neurofilament%20light%20chain%20levels.%22%2C%22date%22%3A%222024%5C%2F04%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3174%5C%2Fajnr.A8154%22%2C%22ISSN%22%3A%220195-6108%2C%201936-959X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.ajnr.org%5C%2Fcontent%5C%2F45%5C%2F4%5C%2F494%22%2C%22collections%22%3A%5B%22P66W67T8%22%2C%229L2KHJ5X%22%2C%22F2AGIUQU%22%2C%22XTA6KS7L%22%2C%22PCMV2W5C%22%2C%22S58TGFSV%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A54Z%22%7D%7D%2C%7B%22key%22%3A%22UU8C3WGR%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bastiancich%20et%20al.%22%2C%22parsedDate%22%3A%222024-11-28%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBastiancich%2C%20C.%2C%20Snacel-Fazy%2C%20E.%2C%20Fernandez%2C%20S.%2C%20Robert%2C%20S.%2C%20Stacchini%2C%20R.%2C%20Plantureux%2C%20L.%2C%20Boissonneau%2C%20S.%2C%20Testud%2C%20B.%2C%20Guillet%2C%20B.%2C%20Debarbieux%2C%20F.%2C%20Luche%2C%20H.%2C%20Figarella-Branger%2C%20D.%2C%20Est%26%23xE8%3Bve%2C%20M.-A.%2C%20Tabouret%2C%20E.%2C%20%26amp%3B%20Tchoghandjian%2C%20A.%20%282024%29.%20Tailoring%20glioblastoma%20treatment%20based%20on%20longitudinal%20analysis%20of%20post-surgical%20tumor%20microenvironment.%20%26lt%3Bi%26gt%3BJournal%20of%20Experimental%20%26amp%3B%20Clinical%20Cancer%20Research%3A%20CR%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B43%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20311.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13046-024-03231-4%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13046-024-03231-4%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Tailoring%20glioblastoma%20treatment%20based%20on%20longitudinal%20analysis%20of%20post-surgical%20tumor%20microenvironment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chiara%22%2C%22lastName%22%3A%22Bastiancich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emmanuel%22%2C%22lastName%22%3A%22Snacel-Fazy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Samantha%22%2C%22lastName%22%3A%22Fernandez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22St%5Cu00e9phane%22%2C%22lastName%22%3A%22Robert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roberta%22%2C%22lastName%22%3A%22Stacchini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L%5Cu00e9a%22%2C%22lastName%22%3A%22Plantureux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00e9bastien%22%2C%22lastName%22%3A%22Boissonneau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Guillet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franck%22%2C%22lastName%22%3A%22Debarbieux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Herv%5Cu00e9%22%2C%22lastName%22%3A%22Luche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominique%22%2C%22lastName%22%3A%22Figarella-Branger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie-Anne%22%2C%22lastName%22%3A%22Est%5Cu00e8ve%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emeline%22%2C%22lastName%22%3A%22Tabouret%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aur%5Cu00e9lie%22%2C%22lastName%22%3A%22Tchoghandjian%22%7D%5D%2C%22abstractNote%22%3A%22Glioblastoma%20%28GBM%29%2C%20an%20incurable%20primary%20brain%20tumor%2C%20typically%20requires%20surgical%20intervention%20followed%20by%20chemoradiation%3B%20however%2C%20recurrences%20remain%20fatal.%20Our%20previous%20work%20demonstrated%20that%20a%20nanomedicine%20hydrogel%20%28GemC12-LNC%29%20delays%20recurrence%20when%20administered%20post-surgery.%20However%2C%20tumor%20debulking%20also%20triggers%20time-dependent%20immune%20reactions%20that%20promote%20recurrence%20at%20the%20resection%20cavity%20borders.%20We%20hypothesized%20that%20combining%20the%20hydrogel%20with%20an%20immunomodulatory%20drug%20could%20enhance%20therapeutic%20outcomes.%20A%20thorough%20characterization%20of%20the%20post-surgical%20microenvironment%20%28SMe%29%20is%20crucial%20to%20guide%20combinatorial%20approaches.In%20this%20study%2C%20we%20performed%20cellular%20resolution%20imaging%2C%20flow%20cytometry%20and%20spatial%20hyperplexed%20immunofluorescence%20imaging%20to%20characterize%20the%20SMe%20in%20a%20syngeneic%20mouse%20model%20of%20tumor%20resection.%20Owing%20to%20our%20dynamic%20approach%2C%20we%20observed%20transient%20opening%20of%20the%20blood-brain%20barrier%20%28BBB%29%20during%20the%20first%20week%20after%20surgery.%20BBB%20permeability%20post-surgery%20was%20also%20confirmed%20in%20GBM%20patients.%20In%20our%20murine%20model%2C%20we%20also%20observed%20changes%20in%20immune%20cell%20morphology%20and%20spatial%20location%20post-surgery%20over%20time%20in%20resected%20animals%20as%20well%20as%20the%20accumulation%20of%20reactive%20microglia%20and%20anti-inflammatory%20macrophages%20in%20recurrences%20compared%20to%20unresected%20tumors%20since%20the%20first%20steps%20of%20recurrence%20growth.%20Therefore%20we%20investigated%20whether%20starting%20a%20systemic%20treatment%20with%20the%20SMAC%20mimetic%20small%20molecule%20%28GDC-0152%29%20directly%20after%20surgery%20would%20be%20beneficial%20for%20enhancing%20microglial%20anti-tumoral%20activity%20and%20decreasing%20the%20number%20of%20anti-inflammatory%20macrophages%20around%20the%20GemC12-LNC%20hydrogel-loaded%20tumor%20cavity.%20The%20immunomodulatory%20effects%20of%20this%20drug%20combination%20was%20firstly%20shown%20in%20patient-derived%20tumoroids.%20Its%20efficacy%20was%20confirmed%20in%20vivo%20by%20survival%20analysis%20and%20correlated%20with%20reversal%20of%20the%20immune%20profile%20as%20well%20as%20delayed%20tumor%20recurrence.This%20comprehensive%20study%20identified%20critical%20time%20frames%20and%20immune%20cellular%20targets%20within%20the%20SMe%2C%20aiding%20in%20the%20rational%20design%20of%20combination%20therapies%20to%20delay%20recurrence%20onset.%20Our%20findings%20suggest%20that%20post-surgical%20systemic%20injection%20of%20GDC-0152%20in%20combination%20with%20GemC12-LNC%20local%20treatment%20is%20a%20promising%20and%20innovative%20approach%20for%20managing%20GBM%20recurrence%2C%20with%20potential%20for%20future%20translation%20to%20human%20patient.%22%2C%22date%22%3A%222024-11-28%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs13046-024-03231-4%22%2C%22ISSN%22%3A%221756-9966%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22396K8KPR%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Harlay%20et%20al.%22%2C%22parsedDate%22%3A%222024-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHarlay%2C%20V.%2C%20Campello%2C%20C.%2C%20Bequet%2C%20C.%2C%20Petrirena%2C%20G.%2C%20Barrie%2C%20M.%2C%20Appay%2C%20R.%2C%20Arnoux%2C%20I.%2C%20Loosveld%2C%20M.%2C%20Testud%2C%20B.%2C%20Bertucci%2C%20A.%2C%20Tabouret%2C%20E.%2C%20%26amp%3B%20Chinot%2C%20O.%20%282024%29.%20Primary%20central%20nervous%20system%20lymphoma%20with%20initial%20spinal%20cord%20involvement%20%28PCNSL-SC%29%20is%20a%20rare%20entity%3A%204%20case%20reports%20and%20review%20of%20literature.%20%26lt%3Bi%26gt%3BRevue%20Neurologique%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B180%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20224%26%23x2013%3B229.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2023.10.003%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2023.10.003%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Primary%20central%20nervous%20system%20lymphoma%20with%20initial%20spinal%20cord%20involvement%20%28PCNSL-SC%29%20is%20a%20rare%20entity%3A%204%20case%20reports%20and%20review%20of%20literature%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22V.%22%2C%22lastName%22%3A%22Harlay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Campello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Bequet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Petrirena%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Barrie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Appay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22I.%22%2C%22lastName%22%3A%22Arnoux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Loosveld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Bertucci%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Tabouret%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22O.%22%2C%22lastName%22%3A%22Chinot%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.neurol.2023.10.003%22%2C%22ISSN%22%3A%220035-3787%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A52Z%22%7D%7D%2C%7B%22key%22%3A%22S67XSDCJ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222024-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Carle%2C%20X.%2C%20Costes%2C%20C.%2C%20Hak%2C%20J.-F.%2C%20%26amp%3B%20Guye%2C%20M.%20%282024%29.%20Added%20Value%20of%20Ultrahigh-Resolution%207T%20MRI%20in%20Dural%20Arteriovenous%20Fistulas.%20%26lt%3Bi%26gt%3BStroke%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B55%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20e46%26%23x2013%3Be47.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1161%5C%2FSTROKEAHA.123.045930%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1161%5C%2FSTROKEAHA.123.045930%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Added%20Value%20of%20Ultrahigh-Resolution%207T%20MRI%20in%20Dural%20Arteriovenous%20Fistulas%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xavier%22%2C%22lastName%22%3A%22Carle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claire%22%2C%22lastName%22%3A%22Costes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Fran%5Cu00e7ois%22%2C%22lastName%22%3A%22Hak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-03%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1161%5C%2FSTROKEAHA.123.045930%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.ahajournals.org%5C%2Fdoi%5C%2F10.1161%5C%2FSTROKEAHA.123.045930%22%2C%22collections%22%3A%5B%22XTA6KS7L%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A52Z%22%7D%7D%2C%7B%22key%22%3A%22ITHXP2FK%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Testud%20et%20al.%22%2C%22parsedDate%22%3A%222024-11-27%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BTestud%2C%20B.%2C%20Guye%2C%20M.%2C%20Witjas%2C%20T.%2C%20%26amp%3B%20Grimaldi%2C%20S.%20%282024%29.%20Iron%20overload%20revealing%20the%20cytoarchitecture%20of%20the%20red%20nucleus%3A%20A%20case%20study.%20%26lt%3Bi%26gt%3BRevue%20Neurologique%26lt%3B%5C%2Fi%26gt%3B%2C%20S0035-3787%2824%2900660-X.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2024.11.001%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2024.11.001%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Iron%20overload%20revealing%20the%20cytoarchitecture%20of%20the%20red%20nucleus%3A%20A%20case%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Witjas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Grimaldi%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-11-27%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.neurol.2024.11.001%22%2C%22ISSN%22%3A%220035-3787%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22PCMV2W5C%22%2C%22H8UPCNQI%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A51Z%22%7D%7D%2C%7B%22key%22%3A%22S7D2KCE4%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Aita%20et%20al.%22%2C%22parsedDate%22%3A%222022-12-27%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAita%2C%20J.-F.%2C%20Agripnidis%2C%20T.%2C%20Testud%2C%20B.%2C%20Barral%2C%20P.-A.%2C%20Jacquier%2C%20A.%2C%20Reyre%2C%20A.%2C%20Alnuaimi%2C%20A.%2C%20Girard%2C%20N.%2C%20Tradi%2C%20F.%2C%20Habert%2C%20P.%2C%20Gariboldi%2C%20V.%2C%20Collart%2C%20F.%2C%20Bartoli%2C%20A.%2C%20%26amp%3B%20Hak%2C%20J.-F.%20%282022%29.%20Stenting%20in%20Brain%20Hemodynamic%20Injury%20of%20Carotid%20Origin%20Caused%20by%20Type%20A%20Aortic%20Dissection%3A%20Local%20Experience%20and%20Systematic%20Literature%20Review.%20%26lt%3Bi%26gt%3BJournal%20of%20Personalized%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B13%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%2058.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjpm13010058%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjpm13010058%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Stenting%20in%20Brain%20Hemodynamic%20Injury%20of%20Carotid%20Origin%20Caused%20by%20Type%20A%20Aortic%20Dissection%3A%20Local%20Experience%20and%20Systematic%20Literature%20Review%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Fran%5Cu00e7ois%22%2C%22lastName%22%3A%22Aita%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thibault%22%2C%22lastName%22%3A%22Agripnidis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benoit%22%2C%22lastName%22%3A%22Testud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre-Antoine%22%2C%22lastName%22%3A%22Barral%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Jacquier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anthony%22%2C%22lastName%22%3A%22Reyre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ammar%22%2C%22lastName%22%3A%22Alnuaimi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Farouk%22%2C%22lastName%22%3A%22Tradi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Habert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vlad%22%2C%22lastName%22%3A%22Gariboldi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frederic%22%2C%22lastName%22%3A%22Collart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Axel%22%2C%22lastName%22%3A%22Bartoli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Fran%5Cu00e7ois%22%2C%22lastName%22%3A%22Hak%22%7D%5D%2C%22abstractNote%22%3A%22In%20this%20study%2C%20we%20report%20our%20local%20experience%20of%20type%20A%20aortic%20dissections%20in%20patients%20with%20cerebral%20malperfusion%20treated%20with%20carotid%20stenting%20before%20or%20after%20aortic%20surgery%2C%20and%20present%20a%20systematic%20literature%20review%20on%20these%20patients%20treated%20either%20with%20carotid%20stenting%20%28CS%29%20before%20or%20after%20aortic%20surgery%20%28AS%29%20or%20with%20aortic%20and%20carotid%20surgery%20alone%20%28ACS%29.%20We%20report%20on%20patients%20treated%20in%20our%20center%20with%20carotid%20stenting%20for%20brain%20hemodynamic%20injury%20of%20carotid%20origin%20caused%20by%20type%20A%20dissection%20since%202018%2C%20and%20a%20systematic%20review%20was%20conducted%20in%20PubMed%20for%20articles%20published%20from%201990%20to%202021.%20Out%20of%205307%20articles%2C%2019%20articles%20could%20be%20included%20with%20a%20total%20of%2080%20patients%20analyzed%3A%209%20from%20our%20center%2C%2029%20patients%20from%20case%20reports%2C%20and%2051%20patients%20from%20two%20retrospective%20cohorts.%20In%20total%2C%208%20patients%20were%20treated%20by%20stenting%20first%2C%2072%20by%20surgery%20first%2C%20and%207%20by%20stenting%20after%20surgery.%20The%20mean%20age%3B%20initial%20NIHSS%20score%3B%20time%20from%20symptom%20onset%20to%20treatment%3B%20post-treatment%20clinical%20improvement%3B%20post-treatment%20clinical%20worsening%3B%20mortality%20rate%3B%20follow-up%20duration%3B%20and%20follow-up%20mRS%20were%2C%20respectively%2C%20for%20each%20group%20%28local%20cohort%2C%20CS%20before%20AS%2C%20ACS%2C%20CS%20after%20AS%29%3A%2071.2%20%5Cu00b1%205.3%20yo%2C%2065.5%20%5Cu00b1%2011.0%20yo%3B%2065.3%20%5Cu00b1%2013.1%20yo%2C%2068.7%20%5Cu00b1%205.8%20yo%3B%204%20%5Cu00b1%208.4%2C%2011.3%20%5Cu00b1%208.5%2C%2014.3%20%5Cu00b1%208.0%2C%200%3B%2011.8%20%5Cu00b1%2014.3%20h%2C%2021%20%5Cu00b1%2039.3%20h%2C%2013.6%20%5Cu00b1%2017.8%20h%2C%2013%20%5Cu00b1%2017.2%20h%3B%2056%25%2C%2071%25%2C%2086%25%2C%2057%25%3B%2011%25%2C%2028%25%2C%200%25%2C%2014%25%3B%2025%25%2C%2012.3%25%2C%2014%25%2C%2033%25%3B%205.25%20%5Cu00b1%202.9%20months%2C%2054%20months%2C%206.8%20%5Cu00b1%203.8%20months%2C%2014%20%5Cu00b1%2014.4%20months%3B%201%20%5Cu00b1%201%3B%200.25%20%5Cu00b1%200.5%2C%201.3%20%5Cu00b1%200.8%2C%200.68%20%5Cu00b1%200.6.%20Preoperative%20carotid%20stenting%20for%20hemodynamic%20cerebral%20malperfusion%20by%20true%20lumen%20compression%20appears%20to%20be%20feasible%2C%20and%20could%20be%20effective%20and%20safe%2C%20although%20there%20is%20still%20a%20lack%20of%20evidence%20due%20to%20the%20absence%20of%20comparative%20statistical%20analysis.%20The%20literature%2C%20albeit%20growing%2C%20is%20still%20limited%2C%20and%20prospective%20comparative%20studies%20are%20needed.%22%2C%22date%22%3A%222022-12-27%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fjpm13010058%22%2C%22ISSN%22%3A%222075-4426%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KFZ6H27M%22%2C%22W98NEAUQ%22%2C%22CXAMISN8%22%2C%22PCMV2W5C%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A45%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22XWY2NCND%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Joppin%20et%20al.%22%2C%22parsedDate%22%3A%222024-11-20%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJoppin%2C%20V.%2C%20Jourdan%2C%20A.%2C%20Bendahan%2C%20D.%2C%20Soucasse%2C%20A.%2C%20Guye%2C%20M.%2C%20Masson%2C%20C.%2C%20%26amp%3B%20B%26%23xE8%3Bge%2C%20T.%20%282024%29.%20Towards%20a%20better%20understanding%20of%20abdominal%20wall%20biomechanics%3A%20In%20vivo%20relationship%20between%20dynamic%20intra-abdominal%20pressure%20and%20magnetic%20resonance%20imaging%20measurements.%20%26lt%3Bi%26gt%3BClinical%20Biomechanics%20%28Bristol%2C%20Avon%29%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B121%26lt%3B%5C%2Fi%26gt%3B%2C%20106396.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clinbiomech.2024.106396%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clinbiomech.2024.106396%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Towards%20a%20better%20understanding%20of%20abdominal%20wall%20biomechanics%3A%20In%20vivo%20relationship%20between%20dynamic%20intra-abdominal%20pressure%20and%20magnetic%20resonance%20imaging%20measurements%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Victoria%22%2C%22lastName%22%3A%22Joppin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arthur%22%2C%22lastName%22%3A%22Jourdan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Bendahan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andr%5Cu00e9a%22%2C%22lastName%22%3A%22Soucasse%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Catherine%22%2C%22lastName%22%3A%22Masson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thierry%22%2C%22lastName%22%3A%22B%5Cu00e8ge%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20In%20vivo%20mechanical%20behaviour%20of%20the%20abdominal%20wall%20has%20been%20poorly%20characterised%20and%20important%20details%20are%20missing%20regarding%20the%20occurrence%20and%20post-operative%20recurrence%20rate%20of%20hernias%20which%20can%20be%20as%20high%20as%2030%5Cu00a0%25.%20This%20study%20aimed%20to%20assess%20the%20correlation%20between%20abdominal%20wall%20displacement%20and%20intra-abdominal%20pressure%2C%20as%20well%20as%20abdominal%20compliance.%5CnMETHODS%3A%20Eighteen%20healthy%20participants%20performed%20audio-guided%20passive%20%28breathing%29%20and%20active%20%28coughing%2C%20Valsalva%20maneuver%29%20exercises.%20Axial%20dynamic%20changes%20of%20abdominal%20muscles%20and%20visceral%20area%20were%20measured%20using%20MRI%2C%20and%20intra-abdominal%20pressure%20with%20ingested%20pressure%20sensor.%5CnFINDINGS%3A%20Correlations%20between%20abdominal%20wall%20displacement%20and%20intra-abdominal%20pressure%20were%20specific%20to%20participant%2C%20exercise%2C%20and%20varying%20between%20rectus%20abdominis%20and%20lateral%20muscles.%20Strong%20correlations%20were%20found%20between%20rectus%20abdominis%20displacement%20and%20intra-abdominal%20pressure%20during%20breathing%20%28r%5Cu00a0%3D%5Cu00a00.92%5Cu00a0%5Cu00b1%5Cu00a00.06%29%2C%20as%20well%20as%20lateral%20muscles%20displacement%20with%20intra-abdominal%20pressure%20during%20coughing%20and%20Valsalva%20maneuver%20%28r%5Cu00a0%3D%5Cu00a0-0.98%5Cu00a0%5Cu00b1%5Cu00a00.03%20and%5Cu00a0-%5Cu00a00.94%5Cu00a0%5Cu00b1%5Cu00a00.05%20respectively%29.%20The%20abdominal%20pseudo-compliance%20varied%20greatly%20among%20participants%20during%20muscular%20contraction%2C%20the%20coefficient%20of%20variation%20reaching%20up%20to%2070%5Cu00a0%25.%5CnINTERPRETATION%3A%20The%20combination%20of%20intra-abdominal%20pressure%20and%20dynamic%20MRI%20measurements%20enables%20the%20identification%20of%20participant-specific%20behaviour%20pattern.%20Intra-abdominal%20pressure%20and%20abdominal%20wall%20dynamic%20undergo%20consistent%20and%20predictable%20interactions.%20However%2C%20this%20relationship%20is%20subject-specific%20and%20may%20not%20be%20extrapolated%20to%20other%20individuals.%20Therefore%2C%20both%20intra-abdominal%20pressure%20and%20abdominal%20wall%20motion%20must%20be%20measured%20in%20the%20same%20participant%20in%20order%20to%20accurately%20characterise%20the%20abdominal%20wall%20behaviour.%20These%20results%20are%20of%20great%20importance%20for%20mesh%20design%2C%20surgical%20decision-making%2C%20and%20personalised%20healthcare.%22%2C%22date%22%3A%222024-11-20%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.clinbiomech.2024.106396%22%2C%22ISSN%22%3A%221879-1271%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22NW6SZQBR%22%2C%22XTA6KS7L%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A44%3A11Z%22%7D%7D%2C%7B%22key%22%3A%225YSAXHXM%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sole%20Cruz%20et%20al.%22%2C%22parsedDate%22%3A%222024-03-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSole%20Cruz%2C%20E.%2C%20Stolowy%2C%20N.%2C%20Attia%2C%20R.%2C%20Audoin%2C%20B.%2C%20%26amp%3B%20Demorti%26%23xE8%3Bre%2C%20S.%20%282024%29.%20Acute%20posterior%20ischemic%20optic%20neuropathy%20associated%20with%20a%20hypertensive%20crisis.%20%26lt%3Bi%26gt%3BRevue%20Neurologique%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B180%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20218%26%23x2013%3B219.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2023.12.002%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2023.12.002%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Acute%20posterior%20ischemic%20optic%20neuropathy%20associated%20with%20a%20hypertensive%20crisis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Sole%20Cruz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Stolowy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Attia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Audoin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Demorti%5Cu00e8re%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-03-01%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.neurol.2023.12.002%22%2C%22ISSN%22%3A%220035-3787%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0035378723011529%22%2C%22collections%22%3A%5B%226KPLZTET%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A43%3A52Z%22%7D%7D%2C%7B%22key%22%3A%22JVQG8Z5Y%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Cruz%20et%20al.%22%2C%22parsedDate%22%3A%222024-03-26%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCruz%2C%20E.%20S.%2C%20Fortanier%2C%20E.%2C%20Hilezian%2C%20F.%2C%20Maarouf%2C%20A.%2C%20Bouti%26%23xE8%3Bre%2C%20C.%2C%20Demorti%26%23xE8%3Bre%2C%20S.%2C%20Rico%2C%20A.%2C%20Delmont%2C%20E.%2C%20Pelletier%2C%20J.%2C%20Attarian%2C%20S.%2C%20%26amp%3B%20Audoin%2C%20B.%20%282024%29.%20Factors%20affecting%20the%20topography%20of%20nitrous%20oxide-induced%20neurological%20complications.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Neurology%26lt%3B%5C%2Fi%26gt%3B%2C%20e16291.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fene.16291%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fene.16291%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Factors%20affecting%20the%20topography%20of%20nitrous%20oxide-induced%20neurological%20complications%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%20Sole%22%2C%22lastName%22%3A%22Cruz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Etienne%22%2C%22lastName%22%3A%22Fortanier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frederic%22%2C%22lastName%22%3A%22Hilezian%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adil%22%2C%22lastName%22%3A%22Maarouf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cl%5Cu00e9mence%22%2C%22lastName%22%3A%22Bouti%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Demorti%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Audrey%22%2C%22lastName%22%3A%22Rico%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emilien%22%2C%22lastName%22%3A%22Delmont%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shahram%22%2C%22lastName%22%3A%22Attarian%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Audoin%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20The%20factors%20underlying%20the%20topography%20of%20nitrous%20oxide%20%28N2O%29-induced%20neurological%20complications%20are%20unknown.%5CnMETHODS%3A%20We%20included%20all%20consecutive%20patients%20admitted%20to%20the%20university%20hospital%20of%20Marseille%20for%20N2O-induced%20neurological%20complications%20in%20a%20prospective%20observational%20study.%20Patients%20underwent%20neurological%20examination%2C%20spinal%20cord%20magnetic%20resonance%20imaging%2C%20and%20nerve%20conduction%20studies%20within%20the%20first%204%5Cu2009weeks%20after%20admission.%5CnRESULTS%3A%20In%20total%2C%2061%20patients%20were%20included%3A%2045%25%20with%20myeloneuropathy%2C%2034%25%20with%20isolated%20myelopathy%2C%20and%2021%25%20with%20isolated%20neuropathy.%20On%20multivariable%20analysis%2C%20the%20odds%20of%20myelopathy%20were%20associated%20with%20the%20amount%20of%20weekly%20N2O%20consumption%20%28~600%5Cu2009g%20cylinder%20per%20week%2C%20odds%20ratio%20%5BOR%5D%20%3D%5Cu20091.11%2C%2095%25%20confidence%20interval%20%5BCI%5D%20%3D%5Cu20091.001-1.24%29.%20The%20extent%20of%20the%20myelopathy%20%28number%20of%20vertebral%20segments%29%20was%20correlated%20with%20the%20number%20of%20~600-g%20cylinders%20consumed%20weekly%20%28%5Cu03c1%5Cu2009%3D%5Cu20090.40%2C%20p%5Cu2009%26lt%3B%5Cu20090.005%29.%20The%20odds%20of%20neuropathy%20were%20associated%20with%20the%20duration%20of%20consumption%20%28per%20month%3B%20OR%5Cu2009%3D%5Cu20091.29%2C%2095%25%20CI%5Cu2009%3D%5Cu20091.05-1.58%29.%20Mean%20lower-limb%20motor%20nerve%20amplitude%20was%20correlated%20with%20the%20duration%20of%20consumption%20%28in%20months%3B%20%5Cu03c1%5Cu2009%3D%5Cu2009-0.34%2C%20p%5Cu2009%26lt%3B%5Cu20090.05%29.%5CnCONCLUSIONS%3A%20The%20odds%20of%20myelopathy%20increased%20with%20the%20amount%20of%20N2O%20consumption%2C%20and%20the%20odds%20of%20neuropathy%20increased%20with%20the%20duration%20of%20N2O%20exposure%2C%20which%20suggests%20distinct%20pathophysiological%20mechanisms%20underlying%20these%20two%20neurological%20complications.%22%2C%22date%22%3A%222024-03-26%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fene.16291%22%2C%22ISSN%22%3A%221468-1331%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KJQH9V8M%22%2C%22B4EWFM7E%22%2C%226KPLZTET%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A43%3A51Z%22%7D%7D%2C%7B%22key%22%3A%22G9U7ZF6L%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Cruz%20et%20al.%22%2C%22parsedDate%22%3A%222025%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCruz%2C%20E.%20S.%2C%20Fortanier%2C%20E.%2C%20Michel%2C%20C.%20P.%2C%20Delmont%2C%20E.%2C%20Verschueren%2C%20A.%2C%20Hostin%2C%20M.-A.%2C%20Bendahan%2C%20D.%2C%20%26amp%3B%20Attarian%2C%20S.%20%282025%29.%20Intraepineurial%20Fat%20Fraction%3A%20A%20Novel%20MR%20Neurography-Based%20Biomarker%20in%20Transthyretin%20Amyloidosis%20Polyneuropathy.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Neurology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B32%26lt%3B%5C%2Fi%26gt%3B%284%29.%20pubmedcentral.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fene.70168%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fene.70168%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Intraepineurial%20Fat%20Fraction%3A%20A%20Novel%20MR%20Neurography-Based%20Biomarker%20in%20Transthyretin%20Amyloidosis%20Polyneuropathy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%20Sole%22%2C%22lastName%22%3A%22Cruz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Etienne%22%2C%22lastName%22%3A%22Fortanier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Constance%20P.%22%2C%22lastName%22%3A%22Michel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emilien%22%2C%22lastName%22%3A%22Delmont%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annie%22%2C%22lastName%22%3A%22Verschueren%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marc-Adrien%22%2C%22lastName%22%3A%22Hostin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Bendahan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shahram%22%2C%22lastName%22%3A%22Attarian%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222025%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fene.70168%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Famu.hal.science%5C%2Fhal-05264578%22%2C%22collections%22%3A%5B%22NW6SZQBR%22%2C%22ZP8JD3DQ%22%5D%2C%22dateModified%22%3A%222025-09-19T07%3A43%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22JITMD4XG%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Demortiere%20et%20al.%22%2C%22parsedDate%22%3A%222025-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDemortiere%2C%20S.%2C%20Stolowy%2C%20N.%2C%20Perriguey%2C%20M.%2C%20Boutiere%2C%20C.%2C%20Rico%2C%20A.%2C%20Hilezian%2C%20F.%2C%20Ndjomo-Ndjomo%2C%20B.-R.%2C%20Durozard%2C%20P.%2C%20Stellmann%2C%20J.-P.%2C%20Marignier%2C%20R.%2C%20Boucraut%2C%20J.%2C%20Pelletier%2C%20J.%2C%20Maarouf%2C%20A.%2C%20%26amp%3B%20Audoin%2C%20B.%20%282025%29.%20Diagnostic%20Utility%20of%20Kappa%20Free%20Light%20Chain%20Index%20in%20Adults%20With%20Inaugural%20Optic%20Neuritis.%20%26lt%3Bi%26gt%3BNeurology%28R%29%20Neuroimmunology%20%26amp%3B%20Neuroinflammation%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20e200386.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1212%5C%2FNXI.0000000000200386%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1212%5C%2FNXI.0000000000200386%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Diagnostic%20Utility%20of%20Kappa%20Free%20Light%20Chain%20Index%20in%20Adults%20With%20Inaugural%20Optic%20Neuritis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Demortiere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Natacha%22%2C%22lastName%22%3A%22Stolowy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marine%22%2C%22lastName%22%3A%22Perriguey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clemence%22%2C%22lastName%22%3A%22Boutiere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Audrey%22%2C%22lastName%22%3A%22Rico%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frederic%22%2C%22lastName%22%3A%22Hilezian%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Blaise-Roger%22%2C%22lastName%22%3A%22Ndjomo-Ndjomo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Durozard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan-Patrick%22%2C%22lastName%22%3A%22Stellmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Romain%22%2C%22lastName%22%3A%22Marignier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jos%5Cu00e9%22%2C%22lastName%22%3A%22Boucraut%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adil%22%2C%22lastName%22%3A%22Maarouf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Audoin%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%20AND%20OBJECTIVES%3A%20A%20simple%2C%20quick%2C%20and%20reproducible%20procedure%20for%20distinguishing%20multiple%20sclerosis%20%28MS%29%2C%20myelin%20oligodendrocyte%20glycoprotein%20antibody-associated%20disease%20%28MOGAD%29%2C%20and%20neuromyelitis%20optica%20spectrum%20disorder%20%28NMOSD%29%20at%20inaugural%20optic%20neuritis%20%28ION%29%20could%20be%20highly%20valuable%20in%20guiding%20early%20management.%5CnMETHODS%3A%20We%20included%20all%20adults%20admitted%20to%20the%20MS%20center%20of%20Marseille%20for%20ION%20between%20March%202016%20and%20April%202024%2C%20with%20CSF%20analysis%20including%20the%20kappa%20free%20light%20chain%20%28K-FLC%29%20index.%20Receiver%20operating%20characteristic%20curves%20were%20used%20to%20measure%20the%20diagnostic%20ability%20of%20the%20K-FLC%20index.%5CnRESULTS%3A%20Two%20hundred%20twenty-seven%20adults%20were%20admitted%20for%20ION%3B%20210%20%2893%25%29%20had%20a%20K-FLC%20index%20measurement.%20MS%20was%20diagnosed%20in%2084%20%2840%25%29%3B%20clinically%20isolated%20syndrome%20suggestive%20of%20MS%20in%2077%20%2836.5%25%29%2C%20including%2020%20with%20future%20conversion%20to%20MS%20%28CISwc%29%3B%20MOGAD%20in%2026%20%2812.5%25%29%3B%20NMOSD%20in%2013%20%286%25%29%3B%20and%20other%20inflammatory%20disorders%20in%2010%20%285%25%29.%20A%20K-FLC%20index%20%5Cu22656.7%20differentiated%20MS%5C%2FCISwc%20from%20other%20diagnoses%20with%20specificity%2086%25%20and%20sensitivity%2095%25%20%28area%20under%20the%20curve%20%5BAUC%5D%200.94%29.%20A%20K-FLC%20index%20%26lt%3B4.9%20differentiated%20MOGAD%20from%20other%20diagnoses%20with%20specificity%2063%25%20and%20sensitivity%2092%25%20%28AUC%200.78%29%20and%20MOGAD%20from%20MS%5C%2FCISwc%20with%20specificity%2096%25%20and%20sensitivity%2092%25%20%28AUC%200.97%29.%20Among%20all%20patients%2C%2093%20%2844%25%29%20had%20a%20K-FLC%20index%20%26lt%3B4.9%3A%2024%20of%20these%20%2826%25%29%20had%20MOGAD%20and%205%20%285.5%25%29%20MS%5C%2FCISwc.%20Among%20the%20remaining%20patients%20with%20a%20K-FLC%20index%20%5Cu22654.9%20%28n%20%3D%20117%29%2C%202%20%281.7%25%29%20had%20MOGAD%20%28K-FLC%20index%20of%207.9%20and%2016.2%29%20and%2099%20%2885%25%29%20MS%5C%2FCISwc.%20Among%20patients%20with%20normal%20MRI%20%28n%20%3D%2096%29%2C%2073%20%2876%25%29%20had%20a%20K-FLC%20index%20%26lt%3B4.9%3A%2022%20of%20these%20%2830%25%29%20had%20MOGAD%2C%20and%20none%20showed%20conversion%20to%20MS.%20Among%20the%20remaining%20patients%20with%20a%20K-FLC%20index%20%5Cu22654.9%20%28n%20%3D%2023%29%2C%202%20%288.5%25%29%20had%20MOGAD%20and%207%20%2830.5%25%29%20showed%20conversion%20to%20MS.%20The%20K-FLC%20index%20did%20not%20differentiate%20NMOSD%20from%20other%20diagnoses%20and%20only%20moderately%20differentiated%20NMO%20from%20MS%5C%2FCISwc%20%28AUC%200.80%29.%5CnDISCUSSION%3A%20The%20K-FLC%20index%20is%20an%20accessible%20biomarker%20to%20guide%20early%20diagnosis%20in%20patients%20with%20ION.%20The%20probability%20of%20MOGAD%20in%20patients%20with%20ION%20and%20a%20K-FLC%20index%20%5Cu22654.9%20is%20low%20even%20in%20case%20of%20normal%20brain%5C%2Fspinal%20cord%20MRI.%5CnCLASSIFICATION%20OF%20EVIDENCE%3A%20This%20study%20provides%20Class%20II%20evidence%20that%20for%20patients%20with%20ION%2C%20the%20K-FLC%20index%20can%20distinguish%20between%20MS%5C%2FCISwc%20and%20MOGAD.%22%2C%22date%22%3A%222025-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1212%5C%2FNXI.0000000000200386%22%2C%22ISSN%22%3A%222332-7812%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KJQH9V8M%22%2C%22B4EWFM7E%22%2C%226KPLZTET%22%2C%229L2KHJ5X%22%5D%2C%22dateModified%22%3A%222025-09-16T09%3A10%3A58Z%22%7D%7D%2C%7B%22key%22%3A%224X78A5BN%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Joppin%20et%20al.%22%2C%22parsedDate%22%3A%222025-08-20%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJoppin%2C%20V.%2C%20Masson%2C%20C.%2C%20Bendahan%2C%20D.%2C%20%26amp%3B%20Bege%2C%20T.%20%282025%29.%20A%20review%20of%20ventral%20hernia%20biomechanics.%20%26lt%3Bi%26gt%3BJournal%20of%20the%20Mechanical%20Behavior%20of%20Biomedical%20Materials%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B173%26lt%3B%5C%2Fi%26gt%3B%2C%20107159.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jmbbm.2025.107159%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jmbbm.2025.107159%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20review%20of%20ventral%20hernia%20biomechanics%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Victoria%22%2C%22lastName%22%3A%22Joppin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Catherine%22%2C%22lastName%22%3A%22Masson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Bendahan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thierry%22%2C%22lastName%22%3A%22Bege%22%7D%5D%2C%22abstractNote%22%3A%22Despite%20advancements%20in%20surgical%20techniques%2C%20hernia%20recurrence%20rates%20remain%20high%2C%20underscoring%20the%20need%20for%20improved%20understanding%20of%20abdominal%20wall%20behaviour.%20While%20surgeons%20are%20aware%20of%20many%20factors%20contributing%20to%20hernia%20occurrence%20%28e.g%20obesity%2C%20smoking%2C%20surgical%20technique%20or%20site%20infection%29%2C%20it%20would%20be%20of%20interest%20to%20consider%20it%20as%20a%20biomechanical%20pathology.%20Indeed%2C%20an%20abdominal%20hernia%20arises%20from%20an%20imbalance%20between%20abdominal%20wall%20deformability%20and%20applied%20forces.%20This%20review%20article%20discusses%20how%20biomechanics%20offer%20a%20quantitative%20framework%20for%20assessing%20healthy%20and%20damaged%20tissue%20behaviour%2C%20guiding%20personalised%20surgical%20strategies%20throughout%20the%20pre-%2C%20intra-%2C%20and%20post-operative%20periods.%20The%20abdominal%20wall%20is%20a%20dynamic%2C%20load-bearing%20structure%2C%20continuously%20subjected%20to%20intra-abdominal%20pressure%20and%20mechanical%20stress.%20Its%20biomechanical%20properties%2C%20including%20elasticity%20and%20resistance%20to%20loading%20forces%2C%20dictate%20its%20function%20and%20response%20to%20surgical%20intervention.%20The%20linea%20alba%20is%20the%20stiffest%20component%20experiencing%20the%20highest%20stress%2C%20while%20the%20abdominal%20wall%26%23039%3Bs%20anisotropic%20nature%20influences%20deformation%20patterns.%20Various%20experimental%20and%20computational%20methods%20enable%20biomechanical%20characterisation.%20Hernias%20represent%20mechanical%20failures%20at%20anatomical%20weak%20points.%20While%20surgeons%20qualitatively%20evaluate%20abdominal%20wall%26%23039%3Bs%20biomechanics%20by%20estimating%20deformation%20and%20closure%20forces%2C%20functional%20imaging%20%28elastography%2C%20dynamic%20acquisitions%29%20could%20provide%20objective%20biomechanical%20insights.%20Hernia%20formation%20alters%20abdominal%20wall%20biomechanics%2C%20inducing%20greater%20mobility%20and%20elasticity.%20Surgical%20repair%20fundamentally%20alters%20the%20biomechanics%20of%20the%20abdominal%20wall.%20The%20choice%20of%20defect%26%23039%3Bs%20suturing%20technique%2C%20mesh%20properties%2C%20placement%2C%20overlap%20and%20fixation%20methods%20%28e.g.%20suture%2C%20tacks%29%20significantly%20influence%20mechanical%20outcomes.%20Surgical%20repair%20tends%20to%20restore%20physiological%20biomechanics%20by%20re-establishing%20force%20transmission%20and%20hernia-induced%20excessive%20mobility.%20Suturing%20techniques%2C%20mesh%20selection%20and%20placement%20influence%20mechanical%20outcomes.%20However%2C%20optimal%20results%20require%20implants%20with%20mechanical%20properties%20mimicking%20native%20tissue.%20Lightweight%20meshes%20%28%26lt%3B70%5Cu00a0g%5C%2Fm2%29%20placed%20in%20a%20retrorectus%20position%2C%20combined%20with%20a%20small-bite%20suture%20technique%2C%20have%20been%20associated%20with%20lower%20recurrence%20rates%20and%20improved%20post-operative%20function.%20By%20bridging%20biomechanics%20with%20surgical%20practice%2C%20this%20review%20highlights%20how%20mechanical%20principles%20shape%20hernia%20formation%2C%20diagnosis%2C%20and%20repair.%20A%20deeper%20integration%20of%20biomechanical%20principles%20into%20surgical%20decision-making%20could%20refine%20hernia%20management%20and%20lead%20to%20patient-specific%2C%20mechanics-informed%20strategies.%20For%20surgeons%2C%20this%20knowledge%20is%20not%20just%20academic%20-%20it%20is%20practical%20and%20can%20make%20a%20difference%20to%20patient%20outcomes.%22%2C%22date%22%3A%222025-08-20%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jmbbm.2025.107159%22%2C%22ISSN%22%3A%221878-0180%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22NW6SZQBR%22%5D%2C%22dateModified%22%3A%222025-09-15T13%3A07%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22G9HL6P42%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Agripnidis%20et%20al.%22%2C%22parsedDate%22%3A%222025-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAgripnidis%2C%20T.%2C%20Ayobi%2C%20A.%2C%20Quenet%2C%20S.%2C%20Chaibi%2C%20Y.%2C%20Avare%2C%20C.%2C%20Jacquier%2C%20A.%2C%20Girard%2C%20N.%2C%20Hak%2C%20J.-F.%2C%20Reyre%2C%20A.%2C%20Brun%2C%20G.%2C%20%26amp%3B%20El%20Ahmadi%2C%20A.-A.%20%282025%29.%20Performance%20of%20an%20artificial%20intelligence%20tool%20for%20multi-step%20acute%20stroke%20imaging%3A%20A%20multicenter%20diagnostic%20study.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Radiology%20Open%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%2C%20100678.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ejro.2025.100678%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ejro.2025.100678%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Performance%20of%20an%20artificial%20intelligence%20tool%20for%20multi-step%20acute%20stroke%20imaging%3A%20A%20multicenter%20diagnostic%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thibault%22%2C%22lastName%22%3A%22Agripnidis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angela%22%2C%22lastName%22%3A%22Ayobi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Quenet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yasmina%22%2C%22lastName%22%3A%22Chaibi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christophe%22%2C%22lastName%22%3A%22Avare%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Jacquier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Fran%5Cu00e7ois%22%2C%22lastName%22%3A%22Hak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anthony%22%2C%22lastName%22%3A%22Reyre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gilles%22%2C%22lastName%22%3A%22Brun%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ahmed-Ali%22%2C%22lastName%22%3A%22El%20Ahmadi%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20Several%20artificial%20intelligence%20%28AI%29%20tools%20have%20been%20developed%20to%20assist%20in%20the%20stroke%20imaging%20workflow%2C%20which%20remains%20a%20major%20disease%20of%20the%2021st%20century.%20This%20study%20evaluated%20the%20combined%20performance%20of%20an%20FDA-cleared%20and%20CE-marked%20AI-based%20device%20with%20three%20modules%20designed%20to%20detect%20intracerebral%20hemorrhage%20%28ICH%29%2C%20identify%20large%20vessel%20occlusion%20%28LVO%29%2C%20and%20calculate%20Alberta%20Stroke%20Program%20Early%20CT%20Scores%20%28ASPECTS%29.%5CnMATERIALS%20%26amp%3B%20METHODS%3A%20Non-contrast%20CT%20%28NCCT%29%20and%5C%2For%20computed%20tomography%20angiography%20%28CTA%29%20for%20suspicion%20of%20stroke%20acquired%20at%20La%20Timone%20and%20Nord%20University%20hospitals%20%28Marseille%2C%20France%29%20between%20March%202019%20and%20March%202020%20were%20retrospectively%20collected.%20The%20AI%20tool%2C%20CINA-HEAD%20%28Avicenna.AI%29%2C%20processed%20the%20data%20to%20flag%20ICH%2C%20LVO%2C%20and%20calculate%20ASPECTS.%20The%20results%20were%20compared%20to%20ground%20truth%20evaluations%20by%20four%20expert%20neuroradiologists%20to%20compute%20diagnostic%20performances.%5CnRESULTS%3A%20A%20total%20of%20373%20NCCT%20and%20331%20CTA%20from%20405%20patients%20%28mean%20age%2064.9%5Cu202f%5Cu00b1%5Cu202f18.9%5Cu202fSD%2C%2052.6%5Cu202f%25%20female%29%20were%20included.%20The%20AI%20tool%20achieved%20an%20accuracy%20of%2094.6%5Cu202f%25%20%5B95%5Cu202f%25%20CI%3A%2091.8%5Cu202f%25-96.7%5Cu202f%25%5D%20for%20ICH%20detection%20on%20NCCT%20and%20of%2086.4%5Cu202f%25%20%5B95%5Cu202f%25%20CI%3A%2082.2%5Cu202f%25-89.9%5Cu202f%25%5D%20for%20LVO%20identification%20on%20CTA.%20The%20region-based%20ASPECTS%20analysis%20yielded%20an%20accuracy%20of%2088.6%5Cu202f%25%20%5B95%5Cu202f%25%20CI%3A%2087.8%5Cu202f%25-89.3%5Cu202f%25%5D%20and%20the%20dichotomized%20ASPECTS%20classification%20%28ASPECTS%20%5Cu2265%206%29%20achieved%2080.4%5Cu202f%25%20accuracy.%5CnCONCLUSION%3A%20This%20study%20demonstrates%20the%20reliable%2C%20stepwise%20performance%20of%20an%20AI-based%20stroke%20imaging%20tool%20across%20the%20diagnostic%20cascade%20of%20ICH%20and%20LVO%20detection%20and%20ASPECTS%20scoring.%20Such%20robust%20multi-stage%20evaluation%20supports%20its%20potential%20for%20streamlining%20acute%20stroke%20triage%20and%20decision-making.%22%2C%22date%22%3A%222025-12%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ejro.2025.100678%22%2C%22ISSN%22%3A%222352-0477%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KFZ6H27M%22%2C%22W98NEAUQ%22%5D%2C%22dateModified%22%3A%222025-09-15T13%3A07%3A39Z%22%7D%7D%2C%7B%22key%22%3A%224BSRQP76%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Porto%20et%20al.%22%2C%22parsedDate%22%3A%222025-09-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPorto%2C%20A.%2C%20Court%2C%20A.%2C%20Barral%2C%20P.%20A.%2C%20Boucekine%2C%20M.%2C%20Imbert%2C%20L.%2C%20Gariboldi%2C%20V.%2C%20Jacquier%2C%20A.%2C%20Collart%2C%20F.%2C%20Theron%2C%20A.%2C%20%26amp%3B%20Gaudry%2C%20M.%20%282025%29.%20Evolution%20of%20Aortic%20Root%20Preservation%20After%20Type%20A%20Acute%20Aortic%20Dissection%20Repair%3A%20Impact%20of%20Root-Residual%20Aortic%20Dissection.%20%26lt%3Bi%26gt%3BJournal%20of%20Clinical%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B14%26lt%3B%5C%2Fi%26gt%3B%2817%29%2C%206274.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm14176274%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm14176274%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Evolution%20of%20Aortic%20Root%20Preservation%20After%20Type%20A%20Acute%20Aortic%20Dissection%20Repair%3A%20Impact%20of%20Root-Residual%20Aortic%20Dissection%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alizee%22%2C%22lastName%22%3A%22Porto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Axel%22%2C%22lastName%22%3A%22Court%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%20Antoine%22%2C%22lastName%22%3A%22Barral%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mohamed%22%2C%22lastName%22%3A%22Boucekine%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Imbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vlad%22%2C%22lastName%22%3A%22Gariboldi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Jacquier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frederic%22%2C%22lastName%22%3A%22Collart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Theron%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marine%22%2C%22lastName%22%3A%22Gaudry%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20The%20management%20of%20the%20aortic%20root%20in%20type%20A%20aortic%20dissection%20%28TAAD%29%20is%20challenging.%20Conservative%20aortic%20root%20repair%20is%20considered%20a%20reasonable%20option%20in%20most%20cases.%20This%20study%20aimed%20to%20analyze%20medium-term%20mortality%20and%20aortic%20root%20reintervention%20after%20TAAD.%20Methods%3A%20All%20patients%20with%20TAAD%20underwent%20prospective%20follow-ups%20between%202017%20and%202021.%20The%20primary%20endpoint%20was%20the%20increase%20in%20aortic%20root%20diameter%20and%20the%20rate%20of%20proximal%20root%20reintervention.%20The%20secondary%20endpoints%20were%20the%20risk%20factor%20and%20location%20for%20root-RAD%2C%20and%20risk%20factors%20for%20severe%20and%20moderate%20AR%20and%20mortality%20during%20follow-up.%20Results%3A%20A%20total%20of%20210%20patients%20were%20included%2C%20of%20which%20166%20%2879.0%25%29%20did%20not%20have%20root-RAD%20and%2044%20%2821.0%25%29%20had%20root-RAD%20after%20supracoronary%20aortic%20replacement.%20After%20a%20mean%20follow-up%20of%2041.1%20months%20%280-60%29%2C%20four%20patients%20%281.8%25%29%20died.%20No%20cases%20of%20aortic%20root%20rupture%20were%20reported.%20Two%20patients%20in%20the%20root-RAD%20group%20underwent%20aortic%20root%20reoperation.%20The%20aortic%20root%20diameter%20increased%20by%200.5%20mm%5C%2Fyear%20and%200.09%20mm%5C%2Fyear%20in%20the%20root-RAD%20and%20no-root-RAD%20groups%2C%20respectively%20%28p%20%3D%200.18%29.%20Root-RAD%20was%20a%20risk%20factor%20for%20severe%20AR%20%28HR%2019.6%3B%2095%25CI%3A%201.6-2.7%3B%20p%20%3D%200.05%29%20and%20an%20independent%20risk%20factor%20for%20moderate%20AR%20%28HR%2023.0%3B%2095%25CI%3A%202.8-2.9%3B%20p%20%3D%200.009%29.%20Conclusions%3A%20Without%20increasing%20long-term%20mortality%2C%20root-RAD%20increases%20the%20risks%20of%20AR%20and%20subsequent%20aortic%20root%20reintervention.%20Long-term%20follow-up%20is%20essential%20for%20monitoring%20aortic%20valve%20function.%22%2C%22date%22%3A%222025-09-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fjcm14176274%22%2C%22ISSN%22%3A%222077-0383%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KFZ6H27M%22%5D%2C%22dateModified%22%3A%222025-09-15T13%3A05%3A57Z%22%7D%7D%2C%7B%22key%22%3A%22LWS8WTYI%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Jougleux%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJougleux%2C%20C.%2C%20Joly%2C%20H.%2C%20Brissard%2C%20H.%2C%20Lenne%2C%20B.%2C%20Fran%26%23xE7%3Bois%2C%20S.%2C%20Hamelin%2C%20F.%2C%20Derache%2C%20N.%2C%20Morin%2C%20J.%2C%20Reuter%2C%20F.%2C%20Colamarino%2C%20R.%2C%20%26amp%3B%20Ruet%2C%20A.%20%282024%29.%20French%20consensus%20procedure%20for%20neuropsychological%20assessment%20in%20multiple%20sclerosis.%20%26lt%3Bi%26gt%3BRevue%20Neurologique%26lt%3B%5C%2Fi%26gt%3B%2C%20S0035-3787%2824%2900558-7.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2024.06.005%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.neurol.2024.06.005%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22French%20consensus%20procedure%20for%20neuropsychological%20assessment%20in%20multiple%20sclerosis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Jougleux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Joly%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Brissard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Lenne%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Fran%5Cu00e7ois%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Hamelin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Derache%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Morin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Reuter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Colamarino%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Ruet%22%7D%5D%2C%22abstractNote%22%3A%22Cognitive%20impairment%20is%20one%20of%20the%20invisible%20symptoms%20of%20Multiple%20sclerosis%20%28MS%29%2C%20which%20could%20be%20associated%20with%20depression%2C%20unemployment%2C%20reduced%20social%20interaction%2C%20inability%20to%20drive%2C%20and%20compromised%20quality%20of%20life.%20Moreover%2C%20the%20presence%20of%20cognitive%20impairment%20can%20be%20considered%20as%20a%20long-term%20prognostic%20factor%20and%20in%20the%20follow-up%20of%20disability.%20So%2C%20cognitive%20assessment%20is%20a%20crucial%20element%20in%20clinical%20follow-up%20of%20patients%20with%20MS%20%28pwMS%29.%20International%20recommendations%20mention%20the%20use%20of%20the%20Brief%20International%20Cognitive%20Assessment%20in%20MS%20%28BICAMS%29.%20The%20BICAMS%2C%20that%20has%20been%20recently%20validated%20in%20French%20is%20a%20brief%20non-exhaustive%20assessment%2C%20developed%20as%20a%20short%20screening%20battery%2C%20hence%20needing%20other%20supplemented%20tests.%20The%20present%20paper%20aims%20to%20propose%20a%20consensus%2C%20approved%20by%20expert%20French%20consensus%20from%20the%20Cognition%20group%20of%20the%20SF-SEP%20%28http%3A%5C%2F%5C%2Fsfsep.org%20%5BSoci%5Cu00e9t%5Cu00e9%20Francophone%20de%20la%20Scl%5Cu00e9rose%20en%20Plaques%5D%29%2C%20for%20cognitive%20assessment%20of%20pwMS%20suggesting%20the%20tools%20that%20should%20be%20used%20in%20order%20to%20apprehend%20the%20other%20cognitive%20impairments%20that%20could%20appear%20in%20MS.%22%2C%22date%22%3A%222024-07-12%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.neurol.2024.06.005%22%2C%22ISSN%22%3A%220035-3787%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22DWGHA69D%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pinto%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPinto%2C%20J.%2C%20McGee%2C%20A.%2C%20Mattern%2C%20H.%2C%20Markenroth%20Bloch%2C%20K.%2C%20Haast%2C%20R.%20A.%20M.%2C%20K%26%23xFC%3Bstner%2C%20T.%2C%20%26amp%3B%20Vannesjo%2C%20S.%20J.%20%282024%29.%20ESMRMB%202024%20focus%20topic%20%26%23x201C%3BMR%20Beyond%20Structures%3A%26%23xA0%3BThe%20dynamic%20body%20at%20different%20scales.%26%23x201D%3B%20%26lt%3Bi%26gt%3BMagnetic%20Resonance%20Materials%20in%20Physics%2C%20Biology%20and%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B37%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20319%26%23x2013%3B319.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10334-024-01175-6%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10334-024-01175-6%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22ESMRMB%202024%20focus%20topic%20%5Cu201cMR%20Beyond%20Structures%3A%5Cu00a0The%20dynamic%20body%20at%20different%20scales%5Cu201d%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joana%22%2C%22lastName%22%3A%22Pinto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Allison%22%2C%22lastName%22%3A%22McGee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hendrik%22%2C%22lastName%22%3A%22Mattern%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karin%22%2C%22lastName%22%3A%22Markenroth%20Bloch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roy%20A.%20M.%22%2C%22lastName%22%3A%22Haast%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22K%5Cu00fcstner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%20Johanna%22%2C%22lastName%22%3A%22Vannesjo%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-07-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10334-024-01175-6%22%2C%22ISSN%22%3A%221352-8661%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10334-024-01175-6%22%2C%22collections%22%3A%5B%22FBQIKF54%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A45Z%22%7D%7D%2C%7B%22key%22%3A%22LWVY9B6Y%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Chakraborty%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BChakraborty%2C%20S.%2C%20Lee%2C%20S.%20K.%2C%20Arnold%2C%20S.%20M.%2C%20Haast%2C%20R.%20A.%20M.%2C%20Khan%2C%20A.%20R.%2C%20%26amp%3B%20Schmitz%2C%20T.%20W.%20%282024%29.%20Focal%20acetylcholinergic%20modulation%20of%20the%20human%20midcingulo-insular%20network%20during%20attention%3A%20Meta-analytic%20neuroimaging%20and%20behavioral%20evidence.%20%26lt%3Bi%26gt%3BJournal%20of%20Neurochemistry%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B168%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%20397%26%23x2013%3B413.%20openaccess.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjnc.15990%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjnc.15990%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Focal%20acetylcholinergic%20modulation%20of%20the%20human%20midcingulo-insular%20network%20during%20attention%3A%20Meta-analytic%20neuroimaging%20and%20behavioral%20evidence%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sudesna%22%2C%22lastName%22%3A%22Chakraborty%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sun%20Kyun%22%2C%22lastName%22%3A%22Lee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%20M.%22%2C%22lastName%22%3A%22Arnold%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roy%20A.%20M.%22%2C%22lastName%22%3A%22Haast%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ali%20R.%22%2C%22lastName%22%3A%22Khan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Taylor%20W.%22%2C%22lastName%22%3A%22Schmitz%22%7D%5D%2C%22abstractNote%22%3A%22The%20basal%20forebrain%20cholinergic%20neurons%20provide%20acetylcholine%20to%20the%20cortex%20via%20large%20projections.%20Recent%20molecular%20imaging%20work%20in%20humans%20indicates%20that%20the%20cortical%20cholinergic%20innervation%20is%20not%20uniformly%20distributed%2C%20but%20rather%20may%20disproportionately%20innervate%20cortical%20areas%20relevant%20to%20supervisory%20attention.%20In%20this%20study%2C%20we%20therefore%20reexamined%20the%20spatial%20relationship%20between%20acetylcholinergic%20modulation%20and%20attention%20in%20the%20human%20cortex%20using%20meta-analytic%20strategies%20targeting%20both%20pharmacological%20and%20non-pharmacological%20neuroimaging%20studies.%20We%20found%20that%20pharmaco-modulation%20of%20acetylcholine%20evoked%20both%20increased%20activity%20in%20the%20anterior%20cingulate%20and%20decreased%20activity%20in%20the%20opercular%20and%20insular%20cortex.%20In%20large%20independent%20meta-analyses%20of%20non-pharmacological%20neuroimaging%20research%2C%20we%20demonstrate%20that%20during%20attentional%20engagement%20these%20cortical%20areas%20exhibit%20%281%29%20task-related%20co-activation%20with%20the%20basal%20forebrain%2C%20%282%29%20task-related%20co-activation%20with%20one%20another%2C%20and%20%283%29%20spatial%20overlap%20with%20dense%20cholinergic%20innervations%20originating%20from%20the%20basal%20forebrain%2C%20as%20estimated%20by%20multimodal%20positron%20emission%20tomography%20and%20magnetic%20resonance%20imaging.%20Finally%2C%20we%20provide%20meta-analytic%20evidence%20that%20pharmaco-modulation%20of%20acetylcholine%20also%20induces%20a%20speeding%20of%20responses%20to%20targets%20with%20no%20apparent%20tradeoff%20in%20accuracy.%20In%20sum%2C%20we%20demonstrate%20in%20humans%20that%20acetylcholinergic%20modulation%20of%20midcingulo-insular%20hubs%20of%20the%20ventral%20attention%5C%2Fsalience%20network%20via%20basal%20forebrain%20afferents%20may%20coordinate%20selection%20of%20task%20relevant%20information%2C%20thereby%20facilitating%20cognition%20and%20behavior.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fjnc.15990%22%2C%22ISSN%22%3A%221471-4159%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fjnc.15990%22%2C%22collections%22%3A%5B%22FBQIKF54%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A45Z%22%7D%7D%2C%7B%22key%22%3A%22GV2CMIC2%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Chakraborty%20et%20al.%22%2C%22parsedDate%22%3A%222024-10-18%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BChakraborty%2C%20S.%2C%20Haast%2C%20R.%20A.%20M.%2C%20Onuska%2C%20K.%20M.%2C%20Kanel%2C%20P.%2C%20Prado%2C%20M.%20A.%20M.%2C%20Prado%2C%20V.%20F.%2C%20Khan%2C%20A.%20R.%2C%20%26amp%3B%20Schmitz%2C%20T.%20W.%20%282024%29.%20Multimodal%20gradients%20of%20basal%20forebrain%20connectivity%20across%20the%20neocortex.%20%26lt%3Bi%26gt%3BNature%20Communications%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%208990.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-53148-x%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-53148-x%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Multimodal%20gradients%20of%20basal%20forebrain%20connectivity%20across%20the%20neocortex%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sudesna%22%2C%22lastName%22%3A%22Chakraborty%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roy%20A.%20M.%22%2C%22lastName%22%3A%22Haast%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kate%20M.%22%2C%22lastName%22%3A%22Onuska%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Prabesh%22%2C%22lastName%22%3A%22Kanel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marco%20A.%20M.%22%2C%22lastName%22%3A%22Prado%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vania%20F.%22%2C%22lastName%22%3A%22Prado%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ali%20R.%22%2C%22lastName%22%3A%22Khan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Taylor%20W.%22%2C%22lastName%22%3A%22Schmitz%22%7D%5D%2C%22abstractNote%22%3A%22Cortical%20cholinergic%20projections%20originate%20from%20subregions%20of%20the%20basal%20forebrain%20%28BF%29.%20To%20examine%20its%20organization%20in%20humans%2C%20we%20computed%20multimodal%20gradients%20of%20BF%20connectivity%20by%20combining%207%5Cu2009T%20diffusion%20and%20resting%20state%20functional%20MRI.%20Moving%20from%20anteromedial%20to%20posterolateral%20BF%2C%20we%20observe%20reduced%20tethering%20between%20structural%20and%20functional%20connectivity%20gradients%2C%20with%20the%20lowest%20tethering%20in%20the%20nucleus%20basalis%20of%20Meynert.%20In%20the%20neocortex%2C%20this%20gradient%20is%20expressed%20by%20progressively%20reduced%20tethering%20from%20unimodal%20sensory%20to%20transmodal%20cortex%2C%20with%20the%20lowest%20tethering%20in%20the%20midcingulo-insular%20network%2C%20and%20is%20also%20spatially%20correlated%20with%20the%20molecular%20concentration%20of%20VAChT%2C%20measured%20by%20%5B18F%5Dfluoroethoxy-benzovesamicol%20%28FEOBV%29%20PET.%20In%20mice%2C%20viral%20tracing%20of%20BF%20cholinergic%20projections%20and%20%5B18F%5DFEOBV%20PET%20confirm%20a%20gradient%20of%20axonal%20arborization.%20Altogether%2C%20our%20findings%20reveal%20that%20BF%20cholinergic%20neurons%20vary%20in%20their%20branch%20complexity%2C%20with%20certain%20subpopulations%20exhibiting%20greater%20modularity%20and%20others%20greater%20diffusivity%20in%20the%20functional%20integration%20with%20their%20cortical%20targets.%22%2C%22date%22%3A%222024-10-18%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-024-53148-x%22%2C%22ISSN%22%3A%222041-1723%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22B4EWFM7E%22%2C%22FBQIKF54%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22YKLSGVH9%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bolton%20et%20al.%22%2C%22parsedDate%22%3A%222024-01-31%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBolton%2C%20T.%20A.%20W.%2C%20Van%20De%20Ville%2C%20D.%2C%20R%26%23xE9%3Bgis%2C%20J.%2C%20Witjas%2C%20T.%2C%20Girard%2C%20N.%2C%20Levivier%2C%20M.%2C%20%26amp%3B%20Tuleasca%2C%20C.%20%282024%29.%20Dynamic%20functional%20changes%20upon%20thalamotomy%20in%20essential%20tremor%20depend%20on%20baseline%20brain%20morphometry.%20%26lt%3Bi%26gt%3BScientific%20Reports%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B14%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%202605.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-024-52410-y%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41598-024-52410-y%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Dynamic%20functional%20changes%20upon%20thalamotomy%20in%20essential%20tremor%20depend%20on%20baseline%20brain%20morphometry%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%20A.%20W.%22%2C%22lastName%22%3A%22Bolton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dimitri%22%2C%22lastName%22%3A%22Van%20De%20Ville%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean%22%2C%22lastName%22%3A%22R%5Cu00e9gis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tatiana%22%2C%22lastName%22%3A%22Witjas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Girard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marc%22%2C%22lastName%22%3A%22Levivier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Constantin%22%2C%22lastName%22%3A%22Tuleasca%22%7D%5D%2C%22abstractNote%22%3A%22Patients%20with%20drug-resistant%20essential%20tremor%20%28ET%29%20may%20undergo%20Gamma%20Knife%20stereotactic%20radiosurgical%20thalamotomy%20%28SRS-T%29%2C%20where%20the%20ventro-intermediate%20nucleus%20of%20the%20thalamus%20%28Vim%29%20is%20lesioned%20by%20focused%20beams%20of%20gamma%20radiations%20to%20induce%20clinical%20improvement.%20Here%2C%20we%20studied%20SRS-T%20impacts%20on%20left%20Vim%20dynamic%20functional%20connectivity%20%28dFC%2C%20n%5Cu2009%3D%5Cu200923%20ET%20patients%20scanned%20before%20and%201%5Cu00a0year%20after%20intervention%29%2C%20and%20on%20surface-based%20morphometric%20brain%20features%20%28n%5Cu2009%3D%5Cu200934%20patients%2C%20including%20those%20from%20dFC%20analysis%29.%20In%20matched%20healthy%20controls%20%28HCs%29%2C%20three%20dFC%20states%20were%20extracted%20from%20resting-state%20functional%20MRI%20data.%20In%20ET%20patients%2C%20state%201%20spatial%20stability%20increased%20upon%20SRS-T%20%28F1%2C22%5Cu2009%3D%5Cu200919.13%2C%5Cu00a0p%5Cu2009%3D%5Cu20090.004%29.%20More%20frequent%20expression%20of%20state%203%20over%20state%201%20before%20SRS-T%20correlated%20with%20greater%20clinical%20recovery%20in%20a%20way%20that%20depended%20on%20the%20MR%20signature%20volume%20%28t6%5Cu2009%3D%5Cu20094.6%2C%5Cu00a0p%5Cu2009%3D%5Cu20090.004%29.%20Lower%20pre-intervention%20spatial%20variability%20in%20state%203%20expression%20also%20did%20%28t6%5Cu2009%3D%5Cu2009-%5Cu20094.24%2C%5Cu00a0p%5Cu2009%3D%5Cu20090.005%29%20and%20interacted%20with%20the%20presence%20of%20familial%20ET%20so%20that%20these%20patients%20improved%20less%20%28t6%5Cu2009%3D%5Cu20094.14%2C%5Cu00a0p%5Cu2009%3D%5Cu20090.006%29.%20ET%20morphometric%20profiles%20showed%20significantly%20lower%20similarity%20to%20HCs%20in%2013%20regions%20upon%20SRS-T%20%28z%5Cu2009%5Cu2264%5Cu2009-%5Cu20093.66%2C%5Cu00a0p%5Cu2009%5Cu2264%5Cu20090.022%29%2C%20and%20a%20joint%20analysis%20revealed%20that%20before%20thalamotomy%2C%20morphometric%20similarity%20and%20states%202%5C%2F3%20mean%20spatial%20similarity%20to%20HCs%20were%20anticorrelated%2C%20a%20relationship%20that%20disappeared%20upon%20SRS-T%20%28z%5Cu2009%5Cu2265%5Cu20094.39%2C%5Cu00a0p%5Cu2009%26lt%3B%5Cu20090.001%29.%20Our%20results%20show%20that%20left%20Vim%20functional%20dynamics%20directly%20relates%20to%20upper%20limb%20tremor%20lowering%20upon%20intervention%2C%20while%20morphometry%20instead%20has%20a%20supporting%20role%20in%20reshaping%20such%20dynamics.%22%2C%22date%22%3A%222024-01-31%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41598-024-52410-y%22%2C%22ISSN%22%3A%222045-2322%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22W98NEAUQ%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A43Z%22%7D%7D%2C%7B%22key%22%3A%22LKL8F93N%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Venet%20et%20al.%22%2C%22parsedDate%22%3A%222024-01-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BVenet%2C%20M.%2C%20Lepine%2C%20A.%2C%20Maarouf%2C%20A.%2C%20Biotti%2C%20D.%2C%20Boutiere%2C%20C.%2C%20Casez%2C%20O.%2C%20Cohen%2C%20M.%2C%20Durozard%2C%20P.%2C%20Demorti%26%23xE8%3Bre%2C%20S.%2C%20Giorgi%2C%20L.%2C%20Maillart%2C%20E.%2C%20Mathey%2C%20G.%2C%20Mazzola%2C%20L.%2C%20Rico%2C%20A.%2C%20Camdessanche%2C%20J.-P.%2C%20Deiva%2C%20K.%2C%20Pelletier%2C%20J.%2C%20%26amp%3B%20Audoin%2C%20B.%20%282024%29.%20Control%20of%20disease%20activity%20with%20large%20extended-interval%20dosing%20of%20rituximab%5C%2Focrelizumab%20in%20highly%20active%20pediatric%20multiple%20sclerosis.%20%26lt%3Bi%26gt%3BMultiple%20Sclerosis%20%28Houndmills%2C%20Basingstoke%2C%20England%29%26lt%3B%5C%2Fi%26gt%3B%2C%2013524585231223069.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F13524585231223069%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F13524585231223069%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Control%20of%20disease%20activity%20with%20large%20extended-interval%20dosing%20of%20rituximab%5C%2Focrelizumab%20in%20highly%20active%20pediatric%20multiple%20sclerosis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melany%22%2C%22lastName%22%3A%22Venet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Lepine%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adil%22%2C%22lastName%22%3A%22Maarouf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Damien%22%2C%22lastName%22%3A%22Biotti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cl%5Cu00e9mence%22%2C%22lastName%22%3A%22Boutiere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olivier%22%2C%22lastName%22%3A%22Casez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mikael%22%2C%22lastName%22%3A%22Cohen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Durozard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Demorti%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laetitia%22%2C%22lastName%22%3A%22Giorgi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Maillart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Guillaume%22%2C%22lastName%22%3A%22Mathey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laure%22%2C%22lastName%22%3A%22Mazzola%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Audrey%22%2C%22lastName%22%3A%22Rico%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Philippe%22%2C%22lastName%22%3A%22Camdessanche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kumaran%22%2C%22lastName%22%3A%22Deiva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Audoin%22%7D%5D%2C%22abstractNote%22%3A%22Recent%20studies%20in%20adults%20suggested%20that%20extended-interval%20dosing%20of%20rituximab%5C%2Focrelizumab%20%28RTX%5C%2FOCR%29%20larger%20than%2012%20months%20was%20safe%20and%20could%20improve%20safety.%20This%20was%20an%20observational%20cohort%20study%20of%20very%20active%20pediatric-onset%20multiple%20sclerosis%20%28PoMS%29%20%28median%20%28range%29%20age%2C%2016%20%2812-17%29%20years%29%20treated%20with%20RTX%5C%2FOCR%20with%206%20month%20standard-interval%20dosing%20%28n%20%3D%209%29%20or%20early%20extended-interval%20dosing%20%28n%20%3D%2012%2C%20median%20%28range%29%20interval%2018%20months%20%2812-25%29%29.%20Within%20a%20median%20%28range%29%20follow-up%20of%2031%20%2812-63%29%20months%20after%20RTX%5C%2FOCR%20onset%2C%20one%20patient%20%28standard-interval%29%20experienced%20relapse%20and%20no%20patient%20showed%20disability%20worsening%20or%20new%20T2-weighted%20lesions.%20This%20study%20suggests%20that%20the%20effectiveness%20of%20RTX%5C%2FOCR%20is%20maintained%20with%20a%20median%20extended-interval%20dosing%20of%2018%20months%20in%20patients%20with%20very%20active%20PoMS.%22%2C%22date%22%3A%222024-01-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1177%5C%2F13524585231223069%22%2C%22ISSN%22%3A%221477-0970%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KJQH9V8M%22%2C%22B4EWFM7E%22%2C%226KPLZTET%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A43Z%22%7D%7D%2C%7B%22key%22%3A%22XYAY2VAJ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Castelli%20et%20al.%22%2C%22parsedDate%22%3A%222024-11-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCastelli%2C%20M.%2C%20Maurin%2C%20A.%2C%20Bartoli%2C%20A.%2C%20Dassa%2C%20M.%2C%20Marchi%2C%20B.%2C%20Finance%2C%20J.%2C%20Lagier%2C%20J.-C.%2C%20Million%2C%20M.%2C%20Parola%2C%20P.%2C%20Brouqui%2C%20P.%2C%20Raoult%2C%20D.%2C%20Cortaredona%2C%20S.%2C%20Jacquier%2C%20A.%2C%20Gaubert%2C%20J.-Y.%2C%20%26amp%3B%20Habert%2C%20P.%20%282024%29.%20Author%20Correction%3A%20Prevalence%20and%20risk%20factors%20for%20lung%20involvement%20on%20low-dose%20chest%20CT%20%28LDCT%29%20in%20a%20paucisymptomatic%20population%20of%20247%20patients%20affected%20by%20COVID-19.%20%26lt%3Bi%26gt%3BInsights%20into%20Imaging%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B15%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20266.%20openaccess.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13244-024-01847-w%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13244-024-01847-w%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Author%20Correction%3A%20Prevalence%20and%20risk%20factors%20for%20lung%20involvement%20on%20low-dose%20chest%20CT%20%28LDCT%29%20in%20a%20paucisymptomatic%20population%20of%20247%20patients%20affected%20by%20COVID-19%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Castelli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Maurin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Axel%22%2C%22lastName%22%3A%22Bartoli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Dassa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Baptiste%22%2C%22lastName%22%3A%22Marchi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julie%22%2C%22lastName%22%3A%22Finance%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Christophe%22%2C%22lastName%22%3A%22Lagier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthieu%22%2C%22lastName%22%3A%22Million%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philippe%22%2C%22lastName%22%3A%22Parola%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philippe%22%2C%22lastName%22%3A%22Brouqui%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Didier%22%2C%22lastName%22%3A%22Raoult%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebastien%22%2C%22lastName%22%3A%22Cortaredona%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Jacquier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Yves%22%2C%22lastName%22%3A%22Gaubert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Habert%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-11-08%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs13244-024-01847-w%22%2C%22ISSN%22%3A%221869-4101%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KFZ6H27M%22%2C%22CXAMISN8%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A42Z%22%7D%7D%2C%7B%22key%22%3A%224RM35DVD%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Macchi%20et%20al.%22%2C%22parsedDate%22%3A%222024-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMacchi%2C%20R.%2C%20Kunimasa%2C%20Y.%2C%20Chavet%2C%20P.%2C%20Corcelle%2C%20B.%2C%20Pomportes%2C%20L.%2C%20Fazzari%2C%20C.%2C%20Hays%2C%20A.%2C%20Vercruyssen%2C%20F.%2C%20Rossi%2C%20F.%2C%20Bendahan%2C%20D.%2C%20%26amp%3B%20Nicol%2C%20C.%20%282024%29.%20Effect%20of%20a%20graded%20running%20race%20on%20lower%20limb%20muscle%20damage%2C%20jump%20performance%20and%20muscle%20soreness%20in%20men%20and%20women.%20%26lt%3Bi%26gt%3BScandinavian%20Journal%20of%20Medicine%20%26amp%3B%20Science%20in%20Sports%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B34%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%20e14643.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fsms.14643%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fsms.14643%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Effect%20of%20a%20graded%20running%20race%20on%20lower%20limb%20muscle%20damage%2C%20jump%20performance%20and%20muscle%20soreness%20in%20men%20and%20women%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robin%22%2C%22lastName%22%3A%22Macchi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoko%22%2C%22lastName%22%3A%22Kunimasa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pascale%22%2C%22lastName%22%3A%22Chavet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Baptiste%22%2C%22lastName%22%3A%22Corcelle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Pomportes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camille%22%2C%22lastName%22%3A%22Fazzari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Hays%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabrice%22%2C%22lastName%22%3A%22Vercruyssen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francesca%22%2C%22lastName%22%3A%22Rossi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Bendahan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Nicol%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20Delayed%20structural%20and%20functional%20recovery%20after%20a%2020%5Cu2009km%20graded%20running%20race%20was%20analyzed%20with%20respect%20to%20the%20sex%20effect.%5CnMETHODS%3A%20Thirteen%20female%20and%2014%20male%20recreational%20runners%20completed%20the%20race%20and%20three%20test%20sessions%3A%20one%20before%20%28PRE%29%20and%20two%20after%2C%20once%20on%20Day%201%20or%202%20%28D1-2%29%20and%20then%20on%20Day%203%20or%204%20%28D3-4%29.%20Muscle%20damage%20was%20assessed%20indirectly%20using%20ultrasonography%20to%20quantify%20changes%20in%20cross-sectional%20area%20%28CSA%29%20of%2010%20lower-limb%20muscles.%20Delayed%20onset%20of%20muscle%20soreness%20%28DOMS%29%20was%20assessed%20for%20three%20muscle%20groups.%20Functional%20recovery%20was%20quantified%20by%20kinetic%20analysis%20of%20a%20squat%20jump%20%28SJ%29%20and%20a%20drop%20jump%20%28DJ%29%20test%20performed%20on%20a%20sledge%20ergometer.%20Linear%20mixed%20models%20were%20used%20to%20assess%20control%20group%20reproducibility%20and%20recovery%20patterns%20according%20to%20sex.%5CnRESULTS%3A%20Regardless%20of%20sex%2C%20DOMS%20peaked%20at%20D1-2%20for%20all%20muscle%20groups%20and%20resolved%20at%20D3-4.%20CSA%20was%20increased%20in%20each%20muscle%20group%20until%20D3-4%2C%20especially%20in%20the%20semimembranosus%20muscle.%20A%20specific%20increase%20was%20found%20in%20the%20short%20head%20of%20the%20biceps%20femoris%20in%20women.%20Regardless%20of%20sex%2C%20SJ%20and%20DJ%20performances%20declined%20up%20to%20D3-4.%20Depending%20on%20the%20muscle%2C%20positive%20and%5C%2For%20negative%20correlations%20were%20found%20between%20structural%20and%20functional%20changes.%20Some%20of%20these%20were%20sex-specific.%5CnCONCLUSION%3A%20Structural%20and%20functional%20recovery%20was%20incomplete%20in%20both%20sexes%20up%20to%20D3-4%2C%20although%20DOMS%20had%20disappeared.%20More%20emphasis%20should%20be%20placed%20on%20hamstring%20muscle%20recovery.%20Highlighting%20the%20intermuscular%20compensations%20that%20can%20occur%20during%20multi-joint%20testing%20tasks%2C%20the%20structural-functional%20relationships%20were%20either%20positive%20or%20negative%2C%20muscle-%20and%20sex-dependent.%22%2C%22date%22%3A%222024-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fsms.14643%22%2C%22ISSN%22%3A%221600-0838%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22NW6SZQBR%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22YW85UVPN%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Matias%20et%20al.%22%2C%22parsedDate%22%3A%222024-09-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMatias%2C%20A.%20A.%2C%20Serviente%2C%20C.%20F.%2C%20Decker%2C%20S.%20T.%2C%20Erol%2C%20M.%20E.%2C%20Giuriato%2C%20G.%2C%20Le%20Fur%2C%20Y.%2C%20Nagarajan%2C%20R.%2C%20Bendahan%2C%20D.%2C%20%26amp%3B%20Layec%2C%20G.%20%282024%29.%20Repeatability%20of%20alkaline%20inorganic%20phosphate%20quantification%20in%20the%20skeletal%20muscle%20using%2031P-magnetic%20resonance%20spectroscopy%20at%203%26%23xA0%3BT.%20%26lt%3Bi%26gt%3BNMR%20in%20Biomedicine%26lt%3B%5C%2Fi%26gt%3B%2C%20e5255.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fnbm.5255%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fnbm.5255%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Repeatability%20of%20alkaline%20inorganic%20phosphate%20quantification%20in%20the%20skeletal%20muscle%20using%2031P-magnetic%20resonance%20spectroscopy%20at%203%5Cu00a0T%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexs%20A.%22%2C%22lastName%22%3A%22Matias%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Corinna%20F.%22%2C%22lastName%22%3A%22Serviente%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephen%20T.%22%2C%22lastName%22%3A%22Decker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Muhammet%20Enes%22%2C%22lastName%22%3A%22Erol%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gaia%22%2C%22lastName%22%3A%22Giuriato%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yann%22%2C%22lastName%22%3A%22Le%20Fur%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rajakumar%22%2C%22lastName%22%3A%22Nagarajan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Bendahan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gwenael%22%2C%22lastName%22%3A%22Layec%22%7D%5D%2C%22abstractNote%22%3A%22The%20detection%20of%20a%20secondary%20inorganic%20phosphate%20%28Pi%29%20resonance%2C%20a%20possible%20marker%20of%20mitochondrial%20content%20in%20vivo%2C%20using%20phosphorus%20magnetic%20resonance%20spectroscopy%20%2831P-MRS%29%2C%20poses%20technical%20challenges%20at%203%5Cu00a0Tesla%20%28T%29.%20Overcoming%20these%20challenges%20is%20imperative%20for%20the%20integration%20of%20this%20biomarker%20into%20clinical%20research.%20To%20evaluate%20the%20repeatability%20and%20reliability%20of%20measuring%20resting%20skeletal%20muscle%20alkaline%20Pi%20%28Pialk%29%20using%20with%2031P-MRS%20at%203%5Cu2009T.%20After%20an%20initial%20set%20of%20experiments%20on%20five%20subjects%20to%20optimize%20the%20sequence%2C%20resting%2031P-MRS%20of%20the%20quadriceps%20muscles%20were%20acquired%20on%20two%20visits%20%28~4%5Cu00a0days%20apart%29%20using%20an%20intra-subjects%20design%2C%20from%2013%20sedentary%20to%20moderately%20active%20young%20male%20and%20female%20adults%20%2822%5Cu2009%5Cu00b1%5Cu20093%5Cu00a0years%20old%29%20within%20a%20whole-body%203%5Cu00a0T%20MR%20system.%20Measurement%20variability%20attributed%20to%20changes%20in%20coil%20position%2C%20shimming%20procedure%2C%20and%20spectral%20analysis%20were%20quantified.%2031P-MRS%20data%20were%20acquired%20with%20a%2031P%5C%2F-proton%20%281H%29%20dual-tuned%20surface%20coil%20positioned%20on%20the%20quadriceps%20using%20a%20pulse-acquire%20sequence.%20Test-retest%20absolute%20and%20relative%20repeatability%20was%20analyzed%20using%20the%20coefficient%20of%20variation%20%28CV%29%20and%20intra-class%20correlation%20coefficients%20%28ICC%29%2C%20respectively.%20After%20sequence%20parameter%20optimization%2C%20Pialk%20demonstrated%20high%20intra-subject%20repeatability%20%28CV%3A%2010.6%5Cu2009%5Cu00b1%5Cu20095.4%25%2C%20ICC%3A%200.80%29.%20Proximo-distal%20change%20in%20coil%20position%20along%20the%20length%20of%20the%20quadriceps%20introduced%20Pialk%20quantitation%20variability%20%28CV%3A%2028%5Cu2009%5Cu00b1%5Cu20095%25%29%2C%20due%20to%20magnetic%20field%20inhomogeneity%20with%20more%20distal%20coil%20locations.%20In%20contrast%2C%20Pialk%20measurement%20variability%20due%20to%20repeated%20shims%20from%20the%20same%20muscle%20volume%20%280.40%5Cu2009%5Cu00b1%5Cu20090.09mM%3B%20CV%3A%206.6%25%29%2C%20and%20automated%20spectral%20processing%20%280.37%5Cu2009%5Cu00b1%5Cu20090.01mM%3B%20CV%3A%202.3%25%29%2C%20was%20minor.%20The%20quantification%20of%20Pialk%20in%20skeletal%20muscle%20via%20surface%20coil%2031P-MRS%20at%203%5Cu00a0T%20demonstrated%20excellent%20reproducibility.%20However%2C%20caution%20is%20advised%20against%20placing%20the%20coil%20at%20the%20distal%20part%20of%20the%20quadriceps%20to%20mitigate%20shimming%20inhomogeneity.%22%2C%22date%22%3A%222024-09-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1002%5C%2Fnbm.5255%22%2C%22ISSN%22%3A%221099-1492%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22NW6SZQBR%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22SJBYYZDY%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sallustio%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSallustio%2C%20V.%2C%20Rossi%2C%20M.%2C%20Mandrone%2C%20M.%2C%20Rossi%2C%20F.%2C%20Chiocchio%2C%20I.%2C%20Cerchiara%2C%20T.%2C%20Longo%2C%20E.%2C%20Fratini%2C%20M.%2C%20D%26%23x2019%3BAmico%2C%20L.%2C%20Tromba%2C%20G.%2C%20Malucelli%2C%20E.%2C%20Protti%2C%20M.%2C%20Mercolini%2C%20L.%2C%20Di%20Blasio%2C%20A.%2C%20Aponte%2C%20M.%2C%20Blaiotta%2C%20G.%2C%20Abruzzo%2C%20A.%2C%20Bigucci%2C%20F.%2C%20Luppi%2C%20B.%2C%20%26amp%3B%20Cappadone%2C%20C.%20%282024%29.%20A%20promising%20eco-sustainable%20wound%20dressing%20based%20on%20cellulose%20extracted%20from%20Spartium%20junceum%20L.%20and%20impregnated%20with%20Glycyrrhiza%20glabra%20L%20extract%3A%20Design%2C%20production%20and%20biological%20properties.%20%26lt%3Bi%26gt%3BInternational%20Journal%20of%20Biological%20Macromolecules%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B272%26lt%3B%5C%2Fi%26gt%3B%28Pt%202%29%2C%20132883.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ijbiomac.2024.132883%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ijbiomac.2024.132883%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20promising%20eco-sustainable%20wound%20dressing%20based%20on%20cellulose%20extracted%20from%20Spartium%20junceum%20L.%20and%20impregnated%20with%20Glycyrrhiza%20glabra%20L%20extract%3A%20Design%2C%20production%20and%20biological%20properties%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22V.%22%2C%22lastName%22%3A%22Sallustio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Rossi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Mandrone%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Rossi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22I.%22%2C%22lastName%22%3A%22Chiocchio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Cerchiara%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Longo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Fratini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22D%27Amico%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Tromba%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.%22%2C%22lastName%22%3A%22Malucelli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Protti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22Mercolini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Di%20Blasio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Aponte%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Blaiotta%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Abruzzo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Bigucci%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Luppi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Cappadone%22%7D%5D%2C%22abstractNote%22%3A%22Glycyrrhiza%20glabra%20extract%20is%20widely%20known%20for%20its%20antioxidant%20and%20anti-inflammatory%20properties%20and%20can%20improve%20the%20wound%20healing%20process.%20The%20aim%20of%20this%20work%20was%20to%20shorten%20the%20time%20of%20the%20healing%20process%20by%20using%20an%20eco-sustainable%20wound%20dressing%20based%20on%20Spanish%20broom%20flexible%20cellulosic%20fabric%20by%20impregnation%20with%20G.%20glabra%20extract-loaded%20ethosomes.%20Chemical%20analysis%20of%20G.%20glabra%20extract%20was%20performed%20by%20LC-DAD-MS%5C%2FMS%20and%20its%20encapsulation%20into%20ethosomes%20was%20obtained%20using%20the%20ethanol%20injection%20method.%20Lipid%20vesicles%20were%20characterized%20in%20terms%20of%20size%2C%20polydispersity%20index%2C%20entrapment%20efficiency%2C%20zeta%20potential%2C%20and%20stability.%20In%20vitro%20release%20studies%2C%20biocompatibility%2C%20and%20scratch%20test%20on%203T3%20fibroblasts%20were%20performed.%20Moreover%2C%20the%20structure%20of%20Spanish%20broom%20dressing%20and%20its%20ability%20to%20absorb%20wound%20exudate%20was%20characterized%20by%20Synchrotron%20X-ray%20phase%20contrast%20microtomography%20%28SR-PCmicroCT%29.%20Ethosomes%20showed%20a%20good%20entrapment%20efficiency%2C%20nanometric%20size%2C%20good%20stability%20over%20time%20and%20a%20slow%20release%20of%20polyphenols%20compared%20to%20the%20free%20extract%2C%20and%20were%20not%20cytotoxic.%20Lastly%2C%20the%20results%20revealed%20that%20Spanish%20broom%20wound%20dressing%20loaded%20with%20G.%20glabra%20ethosomes%20is%20able%20to%20accelerate%20wound%20closure%20by%20reducing%20wound%20healing%20time.%20To%20sum%20up%2C%20Spanish%20broom%20wound%20dressing%20could%20be%20a%20potential%20new%20green%20tool%20for%20biomedical%20applications.%22%2C%22date%22%3A%222024-06-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ijbiomac.2024.132883%22%2C%22ISSN%22%3A%221879-0003%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22D3QFCXE7%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Aung%20et%20al.%22%2C%22parsedDate%22%3A%222024-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAung%2C%20N.%2C%20Bartoli%2C%20A.%2C%20Rauseo%2C%20E.%2C%20Cortaredona%2C%20S.%2C%20Sanghvi%2C%20M.%20M.%2C%20Fournel%2C%20J.%2C%20Ghattas%2C%20B.%2C%20Khanji%2C%20M.%20Y.%2C%20Petersen%2C%20S.%20E.%2C%20%26amp%3B%20Jacquier%2C%20A.%20%282024%29.%20Left%20Ventricular%20Trabeculations%20at%20Cardiac%20MRI%3A%20Reference%20Ranges%20and%20Association%20with%20Cardiovascular%20Risk%20Factors%20in%20UK%20Biobank.%20%26lt%3Bi%26gt%3BRadiology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B311%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20e232455.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1148%5C%2Fradiol.232455%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1148%5C%2Fradiol.232455%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Left%20Ventricular%20Trabeculations%20at%20Cardiac%20MRI%3A%20Reference%20Ranges%20and%20Association%20with%20Cardiovascular%20Risk%20Factors%20in%20UK%20Biobank%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nay%22%2C%22lastName%22%3A%22Aung%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Axel%22%2C%22lastName%22%3A%22Bartoli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisa%22%2C%22lastName%22%3A%22Rauseo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebastien%22%2C%22lastName%22%3A%22Cortaredona%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mihir%20M.%22%2C%22lastName%22%3A%22Sanghvi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joris%22%2C%22lastName%22%3A%22Fournel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Badih%22%2C%22lastName%22%3A%22Ghattas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mohammed%20Y.%22%2C%22lastName%22%3A%22Khanji%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Steffen%20E.%22%2C%22lastName%22%3A%22Petersen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Jacquier%22%7D%5D%2C%22abstractNote%22%3A%22Background%20The%20extent%20of%20left%20ventricular%20%28LV%29%20trabeculation%20and%20its%20relationship%20with%20cardiovascular%20%28CV%29%20risk%20factors%20is%20unclear.%20Purpose%20To%20apply%20automated%20segmentation%20to%20UK%20Biobank%20cardiac%20MRI%20scans%20to%20%28a%29%20assess%20the%20association%20between%20individual%20characteristics%20and%20CV%20risk%20factors%20and%20trabeculated%20LV%20mass%20%28LVM%29%20and%20%28b%29%20establish%20normal%20reference%20ranges%20in%20a%20selected%20group%20of%20healthy%20UK%20Biobank%20participants.%20Materials%20and%20Methods%20In%20this%20cross-sectional%20secondary%20analysis%2C%20prospectively%20collected%20data%20from%20the%20UK%20Biobank%20%282006%20to%202010%29%20were%20retrospectively%20analyzed.%20Automated%20segmentation%20of%20trabeculations%20was%20performed%20using%20a%20deep%20learning%20algorithm.%20After%20excluding%20individuals%20with%20known%20CV%20diseases%2C%20White%20adults%20without%20CV%20risk%20factors%20%28reference%20group%29%20and%20those%20with%20preexisting%20CV%20risk%20factors%20%28hypertension%2C%20hyperlipidemia%2C%20diabetes%20mellitus%2C%20or%20smoking%29%20%28exposed%20group%29%20were%20compared.%20Multivariable%20regression%20models%2C%20adjusted%20for%20potential%20confounders%20%28age%2C%20sex%2C%20and%20height%29%2C%20were%20fitted%20to%20evaluate%20the%20associations%20between%20individual%20characteristics%20and%20CV%20risk%20factors%20and%20trabeculated%20LVM.%20Results%20Of%2043%5Cu2009038%20participants%20%28mean%20age%2C%2064%20years%20%5Cu00b1%208%20%5BSD%5D%3B%2022%5Cu2009360%20women%29%2C%2028%5Cu2009672%20individuals%20%28mean%20age%2C%2066%20years%20%5Cu00b1%207%3B%2014%5Cu2009918%20men%29%20were%20included%20in%20the%20exposed%20group%2C%20and%207384%20individuals%20%28mean%20age%2C%2060%20years%20%5Cu00b1%207%3B%204729%20women%29%20were%20included%20in%20the%20reference%20group.%20Higher%20body%20mass%20index%20%28BMI%29%20%28%5Cu03b2%20%3D%200.66%20%5B95%25%20CI%3A%200.63%2C%200.68%5D%3B%20P%20%26lt%3B%20.001%29%2C%20hypertension%20%28%5Cu03b2%20%3D%200.42%20%5B95%25%20CI%3A%200.36%2C%200.48%5D%3B%20P%20%26lt%3B%20.001%29%2C%20and%20higher%20physical%20activity%20level%20%28%5Cu03b2%20%3D%200.15%20%5B95%25%20CI%3A%200.12%2C%200.17%5D%3B%20P%20%26lt%3B%20.001%29%20were%20associated%20with%20higher%20trabeculated%20LVM.%20In%20the%20reference%20group%2C%20the%20median%20trabeculated%20LVM%20was%206.3%20g%20%28IQR%2C%204.7-8.5%20g%29%20for%20men%20and%204.6%20g%20%28IQR%2C%203.4-6.0%20g%29%20for%20women.%20Median%20trabeculated%20LVM%20decreased%20with%20age%20for%20men%20from%206.5%20g%20%28IQR%2C%204.8-8.7%20g%29%20at%20age%2045-50%20years%20to%205.9%20g%20%28IQR%2C%204.3-7.8%20g%29%20at%20age%2071-80%20years%20%28P%20%3D%20.03%29.%20Conclusion%20Higher%20trabeculated%20LVM%20was%20observed%20with%20hypertension%2C%20higher%20BMI%2C%20and%20higher%20physical%20activity%20level.%20Age-%20and%20sex-specific%20reference%20ranges%20of%20trabeculated%20LVM%20in%20a%20healthy%20middle-aged%20White%20population%20were%20established.%20%5Cu00a9%20RSNA%2C%202024%20Supplemental%20material%20is%20available%20for%20this%20article.%20See%20also%20the%20editorial%20by%20Kawel-Boehm%20in%20this%20issue.%22%2C%22date%22%3A%222024-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1148%5C%2Fradiol.232455%22%2C%22ISSN%22%3A%221527-1315%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22KFZ6H27M%22%2C%22CXAMISN8%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22KM8PBXBP%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Licht%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLicht%2C%20C.%2C%20Reichert%2C%20S.%2C%20Bydder%2C%20M.%2C%20Zapp%2C%20J.%2C%20Corella%2C%20S.%2C%20Guye%2C%20M.%2C%20Z%26%23xF6%3Bllner%2C%20F.%20G.%2C%20Schad%2C%20L.%20R.%2C%20%26amp%3B%20Rapacchi%2C%20S.%20%282024%29.%20Low-rank%20reconstruction%20for%20simultaneous%20double%20half-echo%2023Na%20and%20undersampled%2023Na%20multi-quantum%20coherences%20MRI.%20%26lt%3Bi%26gt%3BMagnetic%20Resonance%20in%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B92%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%201440%26%23x2013%3B1455.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.30132%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.30132%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Low-rank%20reconstruction%20for%20simultaneous%20double%20half-echo%2023Na%20and%20undersampled%2023Na%20multi-quantum%20coherences%20MRI%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Licht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simon%22%2C%22lastName%22%3A%22Reichert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mark%22%2C%22lastName%22%3A%22Bydder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jascha%22%2C%22lastName%22%3A%22Zapp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shirley%22%2C%22lastName%22%3A%22Corella%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frank%20G.%22%2C%22lastName%22%3A%22Z%5Cu00f6llner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lothar%20R.%22%2C%22lastName%22%3A%22Schad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stanislas%22%2C%22lastName%22%3A%22Rapacchi%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20To%20develop%20a%20new%20sequence%20to%20simultaneously%20acquire%20Cartesian%20sodium%20%2823Na%29%20MRI%20and%20accelerated%20Cartesian%20single%20%28SQ%29%20and%20triple%20quantum%20%28TQ%29%20sodium%20MRI%20of%20in%20vivo%20human%20brain%20at%207%20T%20by%20leveraging%20two%20dedicated%20low-rank%20reconstruction%20frameworks.%20Theory%20and%20Methods%20The%20Double%20Half-Echo%20technique%20enables%20short%20echo%20time%20Cartesian%2023Na%20MRI%20and%20acquires%20two%20k-space%20halves%2C%20reconstructed%20by%20a%20low-rank%20coupling%20constraint.%20Additionally%2C%20three-dimensional%20%283D%29%2023Na%20Multi-Quantum%20Coherences%20%28MQC%29%20MRI%20requires%20multi-echo%20sampling%20paired%20with%20phase-cycling%2C%20exhibiting%20a%20redundant%20multidimensional%20space.%20Simultaneous%20Autocalibrating%20and%20k-Space%20Estimation%20%28SAKE%29%20were%20used%20to%20reconstruct%20highly%20undersampled%2023Na%20MQC%20MRI.%20Reconstruction%20performance%20was%20assessed%20against%20five-dimensional%20%285D%29%20CS%2C%20evaluating%20structural%20similarity%20index%20%28SSIM%29%2C%20root%20mean%20squared%20error%20%28RMSE%29%2C%20signal-to-noise%20ratio%20%28SNR%29%2C%20and%20quantification%20of%20tissue%20sodium%20concentration%20and%20TQ%5C%2FSQ%20ratio%20in%20silico%2C%20in%20vitro%2C%20and%20in%20vivo.%20Results%20The%20proposed%20sequence%20enabled%20the%20simultaneous%20acquisition%20of%20fully%20sampled%2023Na%20MRI%20while%20leveraging%20prospective%20undersampling%20for%2023Na%20MQC%20MRI.%20SAKE%20improved%20TQ%20image%20reconstruction%20regarding%20SSIM%20by%206%25%20and%20reduced%20RMSE%20by%2035%25%20compared%20to%205D%20CS%20in%20vivo.%20Thanks%20to%20prospective%20undersampling%2C%20the%20spatial%20resolution%20of%2023Na%20MQC%20MRI%20was%20enhanced%20from%208%5Cu00d78%5Cu00d715%5C%5C%208%5C%5Ctimes%208%5C%5Ctimes%2015%20%5C%5C%20mm3%20to%208%5Cu00d78%5Cu00d78%5C%5C%208%5C%5Ctimes%208%5C%5Ctimes%208%20%5C%5C%20mm3%20while%20reducing%20acquisition%20time%20from%202%5Cu00d731%5C%5C%202%5C%5Ctimes%2031%20%5C%5C%20min%20to%202%5Cu00d723%5C%5C%202%5C%5Ctimes%2023%20%5C%5C%20min.%20Conclusion%20The%20proposed%20sequence%2C%20coupled%20with%20low-rank%20reconstructions%2C%20provides%20an%20efficient%20framework%20for%20comprehensive%20whole-brain%20sodium%20MRI%2C%20combining%20TSC%2C%20T2%2A%2C%20and%20TQ%5C%2FSQ%20ratio%20estimations.%20Additionally%2C%20low-rank%20matrix%20completion%20enables%20the%20reconstruction%20of%20highly%20undersampled%2023Na%20MQC%20MRI%2C%20allowing%20for%20accelerated%20acquisition%20or%20enhanced%20spatial%20resolution.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fmrm.30132%22%2C%22ISSN%22%3A%221522-2594%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Fmrm.30132%22%2C%22collections%22%3A%5B%22SK6VWU7K%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22Q3KH8WBU%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Licht%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BLicht%2C%20C.%2C%20Reichert%2C%20S.%2C%20Guye%2C%20M.%2C%20Schad%2C%20L.%20R.%2C%20%26amp%3B%20Rapacchi%2C%20S.%20%282024%29.%20Multidimensional%20compressed%20sensing%20to%20advance%2023Na%20multi-quantum%20coherences%20MRI.%20%26lt%3Bi%26gt%3BMagnetic%20Resonance%20in%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B91%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%20926%26%23x2013%3B941.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.29902%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.29902%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Multidimensional%20compressed%20sensing%20to%20advance%2023Na%20multi-quantum%20coherences%20MRI%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Licht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simon%22%2C%22lastName%22%3A%22Reichert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lothar%20R.%22%2C%22lastName%22%3A%22Schad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stanislas%22%2C%22lastName%22%3A%22Rapacchi%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20Sodium%20%2823Na%29%20multi-quantum%20coherences%20%28MQC%29%20MRI%20was%20accelerated%20using%20three-dimensional%20%283D%29%20and%20a%20dedicated%20five-dimensional%20%285D%29%20compressed%20sensing%20%28CS%29%20framework%20for%20simultaneous%20Cartesian%20single%20%28SQ%29%20and%20triple%20quantum%20%28TQ%29%20sodium%20imaging%20of%20in%20vivo%20human%20brain%20at%203.0%20and%207.0%20T.%20Theory%20and%20Methods%203D%2023Na%20MQC%20MRI%20requires%20multi-echo%20paired%20with%20phase-cycling%20and%20exhibits%20thus%20a%20multidimensional%20space.%20A%20joint%20reconstruction%20framework%20to%20exploit%20the%20sparsity%20in%20all%20imaging%20dimensions%20by%20extending%20the%20conventional%203D%20CS%20framework%20to%205D%20was%20developed.%203D%20MQC%20images%20of%20simulated%20brain%2C%20phantom%20and%20healthy%20brain%20volunteers%20obtained%20from%203.0%20T%20and%207.0%20T%20were%20retrospectively%20and%20prospectively%20undersampled.%20Performance%20of%20the%20CS%20models%20were%20analyzed%20by%20means%20of%20structural%20similarity%20index%20%28SSIM%29%2C%20root%20mean%20squared%20error%20%28RMSE%29%2C%20signal-to-noise%20ratio%20%28SNR%29%20and%20signal%20quantification%20of%20tissue%20sodium%20concentration%20and%20TQ%5C%2FSQ%20ratio.%20Results%20It%20was%20shown%20that%20an%20acceleration%20of%20three-fold%2C%20leading%20to%20less%20than%202%5Cu00d710%5C%5C%202%5C%5Ctimes%2010%20%5C%5C%20min%20of%20scan%20time%20with%20a%20resolution%20of%208%5Cu00d78%5Cu00d720%20mm3%5C%5C%208%5C%5Ctimes%208%5C%5Ctimes%2020%5C%5C%3B%5C%5Cmathrmmm%5E3%20%5C%5C%20at%203.0%20T%2C%20are%20possible.%205D%20CS%20improved%20SSIM%20by%203%25%2C%205%25%2C%201%25%20and%20reduced%20RMSE%20by%2050%25%2C%2030%25%2C%208%25%20for%20in%20vivo%20SQ%2C%20TQ%2C%20and%20TQ%5C%2FSQ%20ratio%20maps%2C%20respectively.%20Furthermore%2C%20for%20the%20first%20time%20prospective%20undersampling%20enabled%20unprecedented%20high%20resolution%20from%208%5Cu00d78%5Cu00d720%20mm3%5C%5C%208%5C%5Ctimes%208%5C%5Ctimes%2020%5C%5C%3B%5C%5Cmathrmmm%5E3%20%5C%5C%20to%206%5Cu00d76%5Cu00d710%20mm3%5C%5C%206%5C%5Ctimes%206%5C%5Ctimes%2010%5C%5C%3B%5C%5Cmathrmmm%5E3%20%5C%5C%20MQC%20images%20of%20in%20vivo%20human%20brain%20at%207.0%20T%20without%20extending%20acquisition%20time.%20Conclusion%205D%20CS%20proved%20to%20allow%20up%20to%20three-fold%20acceleration%20retrospectively%20on%203.0%20T%20data.%202-fold%20acceleration%20was%20demonstrated%20prospectively%20at%207.0%20T%20to%20reach%20higher%20spatial%20resolution%20of%2023Na%20MQC%20MRI.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fmrm.29902%22%2C%22ISSN%22%3A%221522-2594%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Fmrm.29902%22%2C%22collections%22%3A%5B%22SK6VWU7K%22%2C%22XTA6KS7L%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22YG4NEEFH%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brui%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBrui%2C%20E.%20A.%2C%20Badrieva%2C%20Z.%2C%20de%20Mayenne%2C%20C.-A.%2C%20Rapacchi%2C%20S.%2C%20Troalen%2C%20T.%2C%20%26amp%3B%20Bendahan%2C%20D.%20%282024%29.%20Mitigating%20slice%20cross-talk%20in%20multi-slice%20multi-echo%20spin%20echo%20T2%20mapping.%20%26lt%3Bi%26gt%3BMagnetic%20Resonance%20in%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B91%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%202089%26%23x2013%3B2103.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.29987%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.29987%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Mitigating%20slice%20cross-talk%20in%20multi-slice%20multi-echo%20spin%20echo%20T2%20mapping%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ekaterina%20A.%22%2C%22lastName%22%3A%22Brui%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Zilya%22%2C%22lastName%22%3A%22Badrieva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charles-Alexis%22%2C%22lastName%22%3A%22de%20Mayenne%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stanislas%22%2C%22lastName%22%3A%22Rapacchi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Troalen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Bendahan%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20To%20investigate%20whether%20a%20T2%20inter-slice%20variation%20could%20occur%20when%20a%20multi-slice%20multi-echo%20spin%20echo%20%28MESE%29%20sequence%20is%20used%20for%20image%20acquisition%20and%20to%20propose%20an%20enhanced%20method%20for%20reconstructing%20T2%20maps%20that%20can%20effectively%20address%20and%20correct%20these%20variations.%20Methods%20Bloch%20simulations%20were%20performed%20accounting%20for%20the%20direct%20saturation%20effect%20to%20evaluate%20magnetization%20changes%20in%20multi-slice%202D%20MESE%20sequence.%20Experimental%20phantom%20scans%20were%20performed%20to%20validate%20these%20simulations.%20An%20improved%20version%20of%20the%20dictionary-based%20reconstruction%20approach%20was%20proposed%2C%20enabling%20the%20creation%20of%20a%20multi-slice%20dictionary%20of%20echo%20modulation%20curves%20%28EMC%29.%20The%20corresponding%20method%20has%20been%20assayed%20considering%20inter-slice%20T2%20variation%20with%20phantoms%20and%20in%20lower%20leg.%20Results%20Experimental%20and%20numerical%20study%20illustrate%20that%20direct%20saturation%20leads%20to%20a%20bias%20of%20EMCs.%20This%20bias%20during%20the%20T2%20maps%20reconstructions%20using%20original%20single-slice%20EMC-dictionary%20method%20led%20to%20inter-slice%20T2%20variation%20of%202.03%25%20in%20average%20coefficient%20of%20variation%20%28CV%29%20in%20agarose%20phantoms%2C%20and%20up%20to%202.8%25%20in%20vivo%20%28for%20TR%20%3D%202%20s%2C%20slice%20gap%20%3D%200%25%29.%20A%20reduction%20of%20CV%20was%20observed%20when%20increasing%20the%20gap%20up%20to%20100%25%20%280.36%25%20in%20phantoms%2C%20and%20up%20to%201.5%25%20in%20vivo%29%20or%20increasing%20TR%20up%20to%204%20s%20%280.76%25%20in%20phantoms%2C%20and%20up%20to%201.9%25%20in%20vivo%29.%20Matching%20the%20multi-slice%20experimental%20data%20with%20multi-slice%20dictionaries%20provided%20a%20reduced%20CV%20of%200.54%25%20in%20phantoms%20and%20up%20to%202.3%25%20in%20vivo.%20Conclusion%20T2%20values%20quantified%20from%20multi-slice%20MESE%20images%20using%20single-slice%20dictionaries%20are%20biased.%20A%20dedicated%20multi-slice%20EMC%20method%20providing%20the%20appropriate%20dictionaries%20can%20reduce%20the%20inter-slice%20T2%20variation.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fmrm.29987%22%2C%22ISSN%22%3A%221522-2594%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Fmrm.29987%22%2C%22collections%22%3A%5B%226GBQDAVI%22%2C%22NW6SZQBR%22%2C%22SK6VWU7K%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22F2ENYVDV%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Androdias%20et%20al.%22%2C%22parsedDate%22%3A%222024-12-21%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAndrodias%2C%20G.%2C%20L%26%23xFC%3Bnemann%2C%20J.%20D.%2C%20Maillart%2C%20E.%2C%20Amato%2C%20M.%20P.%2C%20Audoin%2C%20B.%2C%20Bruijstens%2C%20A.%20L.%2C%20Bsteh%2C%20G.%2C%20Butzkueven%2C%20H.%2C%20Ciccarelli%2C%20O.%2C%20Cobo-Calvo%2C%20A.%2C%20Derfuss%2C%20T.%2C%20Di%20Pauli%2C%20F.%2C%20Edan%2C%20G.%2C%20Enzinger%2C%20C.%2C%20Geraldes%2C%20R.%2C%20Granziera%2C%20C.%2C%20Hacohen%2C%20Y.%2C%20Hartung%2C%20H.-P.%2C%20Hynes%2C%20S.%2C%20%26%23x2026%3B%20Stankoff%2C%20B.%20%282024%29.%20De-escalating%20and%20discontinuing%20disease-modifying%20therapies%20in%20multiple%20sclerosis.%20%26lt%3Bi%26gt%3BBrain%26lt%3B%5C%2Fi%26gt%3B%2C%20awae409.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbrain%5C%2Fawae409%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbrain%5C%2Fawae409%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22De-escalating%20and%20discontinuing%20disease-modifying%20therapies%20in%20multiple%20sclerosis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G%5Cu00e9raldine%22%2C%22lastName%22%3A%22Androdias%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jan%20D%22%2C%22lastName%22%3A%22L%5Cu00fcnemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Maillart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maria%20Pia%22%2C%22lastName%22%3A%22Amato%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Audoin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arlette%20L%22%2C%22lastName%22%3A%22Bruijstens%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gabriel%22%2C%22lastName%22%3A%22Bsteh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Helmut%22%2C%22lastName%22%3A%22Butzkueven%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olga%22%2C%22lastName%22%3A%22Ciccarelli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alvaro%22%2C%22lastName%22%3A%22Cobo-Calvo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Derfuss%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Di%20Pauli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gilles%22%2C%22lastName%22%3A%22Edan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Enzinger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Geraldes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cristina%22%2C%22lastName%22%3A%22Granziera%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yael%22%2C%22lastName%22%3A%22Hacohen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans-Peter%22%2C%22lastName%22%3A%22Hartung%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sin%5Cu00e9ad%22%2C%22lastName%22%3A%22Hynes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matilde%22%2C%22lastName%22%3A%22Inglese%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ludwig%22%2C%22lastName%22%3A%22Kappos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hanna%22%2C%22lastName%22%3A%22Kuusisto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annette%22%2C%22lastName%22%3A%22Langer-Gould%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melinda%22%2C%22lastName%22%3A%22Magyari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Romain%22%2C%22lastName%22%3A%22Marignier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xavier%22%2C%22lastName%22%3A%22Montalban%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcin%20P%22%2C%22lastName%22%3A%22Mycko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bardia%22%2C%22lastName%22%3A%22Nourbakhsh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jiwon%22%2C%22lastName%22%3A%22Oh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Celia%22%2C%22lastName%22%3A%22Oreja-Guevara%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fredrik%22%2C%22lastName%22%3A%22Piehl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Luca%22%2C%22lastName%22%3A%22Prosperini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jaume%22%2C%22lastName%22%3A%22Sastre-Garriga%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Finn%22%2C%22lastName%22%3A%22Sellebjerg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Krzysztof%22%2C%22lastName%22%3A%22Selmaj%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aksel%22%2C%22lastName%22%3A%22Siva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emma%22%2C%22lastName%22%3A%22Tallantyre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%22%2C%22lastName%22%3A%22van%20Pesch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sandra%22%2C%22lastName%22%3A%22Vukusic%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bianca%22%2C%22lastName%22%3A%22Weinstock-Guttman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frauke%22%2C%22lastName%22%3A%22Zipp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mar%22%2C%22lastName%22%3A%22Tintor%5Cu00e9%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ellen%22%2C%22lastName%22%3A%22Iacobaeus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bruno%22%2C%22lastName%22%3A%22Stankoff%22%7D%5D%2C%22abstractNote%22%3A%22The%20development%20of%20disease-modifying%20therapies%20%28DMTs%29%20for%20the%20treatment%20of%20multiple%20sclerosis%20%28MS%29%20has%20been%20highly%20successful%20in%20recent%20decades.%20It%20is%20now%20widely%20accepted%20that%20early%20initiation%20of%20DMTs%20after%20disease%20onset%20is%20associated%20with%20a%20better%20long-term%20prognosis.%20However%2C%20the%20question%20of%20when%20and%20how%20to%20de-escalate%20or%20discontinue%20DMTs%20remains%20open%20and%20critical.%20This%20topic%20was%20discussed%20during%20an%20international%20focused%20workshop%20organized%20by%20the%20European%20Committee%20for%20Treatment%20and%20Research%20in%20Multiple%20Sclerosis%20%28ECTRIMS%29%20in%202023.%20The%20aim%20was%20to%20review%20the%20current%20evidence%20on%20the%20rationale%20for%2C%20but%20also%20the%20potential%20pitfalls%20of%2C%20treatment%20de-escalation%20in%20MS.%20Several%20clinical%20scenarios%20emerged%2C%20mainly%20driven%20by%20a%20change%20in%20the%20benefit-risk%20ratio%20of%20DMTs%20over%20the%20course%20of%20the%20disease%20and%20with%20aging.%20The%20workshop%20also%20addressed%20the%20issue%20of%20de-escalation%20by%20the%20type%20of%20DMT%20used%20and%20in%20specific%20situations%20including%20pregnancy%20and%20paediatric%20onset%20MS.%20Finally%2C%20we%20provide%20practical%20guidelines%20for%20selecting%20appropriate%20patients%2C%20defining%20de-escalation%20and%20monitoring%20modalities%2C%20and%20outline%20unmet%20needs%20in%20this%20field.%22%2C%22date%22%3A%222024-12-21%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1093%5C%2Fbrain%5C%2Fawae409%22%2C%22ISSN%22%3A%220006-8950%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbrain%5C%2Fawae409%22%2C%22collections%22%3A%5B%226KPLZTET%22%2C%22B2M3AZVC%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22RWZD4763%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Varoquaux%20et%20al.%22%2C%22parsedDate%22%3A%222024-10-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BVaroquaux%2C%20A.%2C%20Fakhry%2C%20N.%2C%20Scemama%2C%20U.%2C%20%26amp%3B%20Ta%26%23xEF%3Beb%2C%20D.%20%282024%29.%20Differentiation%20of%20vagal%20from%20carotid%20paraganglioma%20on%20unenhanced%20PET%5C%2FCT%3A%20the%20%26%23x201C%3Bsweet%20potato%26%23x201D%3B%20shape%20on%20PET.%20%26lt%3Bi%26gt%3BEuropean%20Journal%20of%20Nuclear%20Medicine%20and%20Molecular%20Imaging%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B51%26lt%3B%5C%2Fi%26gt%3B%2812%29%2C%203799%26%23x2013%3B3801.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00259-024-06776-w%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00259-024-06776-w%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Differentiation%20of%20vagal%20from%20carotid%20paraganglioma%20on%20unenhanced%20PET%5C%2FCT%3A%20the%20%5Cu201csweet%20potato%5Cu201d%20shape%20on%20PET%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arthur%22%2C%22lastName%22%3A%22Varoquaux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Fakhry%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ugo%22%2C%22lastName%22%3A%22Scemama%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Ta%5Cu00efeb%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024-10-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00259-024-06776-w%22%2C%22ISSN%22%3A%221619-7089%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00259-024-06776-w%22%2C%22collections%22%3A%5B%22KBIRKXGV%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A34Z%22%7D%7D%2C%7B%22key%22%3A%22E9LICJTQ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Monestier%20et%20al.%22%2C%22parsedDate%22%3A%222024-05-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BMonestier%2C%20L.%2C%20Del%20Grande%2C%20J.%2C%20Haddad%2C%20R.%2C%20Santini%2C%20L.%2C%20Michel%2C%20J.%2C%20Varoquaux%2C%20A.%2C%20%26amp%3B%20Fakhry%2C%20N.%20%282024%29.%20Correlation%20between%20MRI%20%28DWI%20and%20DCE%29%20and%20cellularity%20of%20parotid%20gland%20pleomorphic%20adenomas.%20%26lt%3Bi%26gt%3BEuropean%20Archives%20of%20Oto-Rhino-Laryngology%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B281%26lt%3B%5C%2Fi%26gt%3B%285%29%2C%202655%26%23x2013%3B2665.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00405-024-08562-8%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00405-024-08562-8%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Correlation%20between%20MRI%20%28DWI%20and%20DCE%29%20and%20cellularity%20of%20parotid%20gland%20pleomorphic%20adenomas%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Monestier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean%22%2C%22lastName%22%3A%22Del%20Grande%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralph%22%2C%22lastName%22%3A%22Haddad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laure%22%2C%22lastName%22%3A%22Santini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Justin%22%2C%22lastName%22%3A%22Michel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arthur%22%2C%22lastName%22%3A%22Varoquaux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Fakhry%22%7D%5D%2C%22abstractNote%22%3A%22Parotid%20pleomorphic%20adenomas%20present%20a%20risk%20of%20recurrence%2C%20higher%20when%20the%20tumour%20is%20a%20hypocellular%20subtype.%20The%20aim%20of%20the%20study%20was%20to%20determine%20whether%20it%20is%20possible%20to%20characterize%20this%20histological%20subtype%20with%20diffusion%20and%20perfusion%20sequences%20of%20the%20preoperative%20MRI.%22%2C%22date%22%3A%222024-05-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00405-024-08562-8%22%2C%22ISSN%22%3A%221434-4726%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00405-024-08562-8%22%2C%22collections%22%3A%5B%22KBIRKXGV%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22RMARCXIW%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Omouri%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BOmouri%2C%20A.%2C%20Rapacchi%2C%20S.%2C%20Duclos%2C%20J.%2C%20Niddam%2C%20R.%2C%20Bellemare%2C%20M.-E.%2C%20%26amp%3B%20Pirr%26%23xF3%3B%2C%20N.%20%282024%29.%203D%20Observation%20of%20Pelvic%20Organs%20with%20Dynamic%20MRI%20Segmentation%3A%20A%20Bridge%20Toward%20Patient-Specific%20Models.%20%26lt%3Bi%26gt%3BInternational%20Urogynecology%20Journal%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B35%26lt%3B%5C%2Fi%26gt%3B%287%29%2C%201389%26%23x2013%3B1397.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00192-024-05817-0%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00192-024-05817-0%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%223D%20Observation%20of%20Pelvic%20Organs%20with%20Dynamic%20MRI%20Segmentation%3A%20A%20Bridge%20Toward%20Patient-Specific%20Models%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adel%22%2C%22lastName%22%3A%22Omouri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stanislas%22%2C%22lastName%22%3A%22Rapacchi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julie%22%2C%22lastName%22%3A%22Duclos%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rapha%5Cu00ebl%22%2C%22lastName%22%3A%22Niddam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marc-Emmanuel%22%2C%22lastName%22%3A%22Bellemare%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Pirr%5Cu00f3%22%7D%5D%2C%22abstractNote%22%3A%22Female%20pelvic%20organ%20prolapses%20are%20common%2C%20but%20their%20treatment%20is%20challenging.%20Notably%2C%20diagnosis%20and%20understanding%20of%20these%20troubles%20remain%20incomplete.%20Tridimensional%20observations%20of%20displacement%20and%20deformation%20of%20the%20pelvic%20organs%20during%20a%20strain%20could%20support%20a%20better%20understanding%20and%20help%20to%20develop%20comprehensive%20tools%20for%20preoperative%20planning.%22%2C%22date%22%3A%222024-07-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00192-024-05817-0%22%2C%22ISSN%22%3A%221433-3023%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00192-024-05817-0%22%2C%22collections%22%3A%5B%22SK6VWU7K%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22AZIJ7JNE%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Jeantin%20et%20al.%22%2C%22parsedDate%22%3A%222024-01-21%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BJeantin%2C%20L.%2C%20Januel%2C%20E.%2C%20Labauge%2C%20P.%2C%20Maillart%2C%20E.%2C%20de%20Seze%2C%20J.%2C%20Z%26%23xE9%3Bphir%2C%20H.%2C%20Pelletier%2C%20J.%2C%20Kerschen%2C%20P.%2C%20Biotti%2C%20D.%2C%20Heinzlef%2C%20O.%2C%20Guilloton%2C%20L.%2C%20Bensa%2C%20C.%2C%20Th%26%23xE9%3Baudin%2C%20M.%2C%20Vukusic%2C%20S.%2C%20Casez%2C%20O.%2C%20Maurousset%2C%20A.%2C%20Laplaud%2C%20D.%2C%20Berger%2C%20E.%2C%20Lebrun-Frenay%2C%20C.%2C%20%26%23x2026%3B%20Louapre%2C%20C.%20%282024%29.%20COVID-19%20outcomes%20in%20patients%20with%20multiple%20sclerosis%3A%20Understanding%20changes%20from%202020%20to%202022.%20%26lt%3Bi%26gt%3BMultiple%20Sclerosis%20%28Houndmills%2C%20Basingstoke%2C%20England%29%26lt%3B%5C%2Fi%26gt%3B%2C%2013524585231218149.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F13524585231218149%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F13524585231218149%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22COVID-19%20outcomes%20in%20patients%20with%20multiple%20sclerosis%3A%20Understanding%20changes%20from%202020%20to%202022%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lina%22%2C%22lastName%22%3A%22Jeantin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Edouard%22%2C%22lastName%22%3A%22Januel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Labauge%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Maillart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00e9r%5Cu00f4me%22%2C%22lastName%22%3A%22de%20Seze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H%5Cu00e9l%5Cu00e8ne%22%2C%22lastName%22%3A%22Z%5Cu00e9phir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean%22%2C%22lastName%22%3A%22Pelletier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philippe%22%2C%22lastName%22%3A%22Kerschen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Damien%22%2C%22lastName%22%3A%22Biotti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olivier%22%2C%22lastName%22%3A%22Heinzlef%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laurent%22%2C%22lastName%22%3A%22Guilloton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Bensa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Th%5Cu00e9audin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sandra%22%2C%22lastName%22%3A%22Vukusic%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olivier%22%2C%22lastName%22%3A%22Casez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aude%22%2C%22lastName%22%3A%22Maurousset%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Laplaud%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22Berger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Lebrun-Frenay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Bourre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Branger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bruno%22%2C%22lastName%22%3A%22Stankoff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Clavelou%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22Thouvenot%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22Manchon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thibault%22%2C%22lastName%22%3A%22Moreau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fran%5Cu00e7ois%22%2C%22lastName%22%3A%22Sellal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Zedet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Papeix%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C%5Cu00e9line%22%2C%22lastName%22%3A%22Louapre%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Epidemiologic%20studies%20on%20coronavirus%20disease%202019%20%28COVID-19%29%20in%20patients%20with%20multiple%20sclerosis%20%28pwMS%29%20have%20focused%20on%20the%20first%20waves%20of%20the%20pandemic%20until%20early%202021.%5CnOBJECTIVES%3A%20We%20aimed%20to%20extend%20these%20data%20from%20the%20onset%20of%20the%20pandemic%20to%20the%20global%20coverage%20by%20vaccination%20in%20summer%202022.%5CnMETHODS%3A%20This%20retrospective%2C%20multicenter%20observational%20study%20analyzed%20COVISEP%20registry%20data%20on%20reported%20COVID-19%20cases%20in%20pwMS%20between%20January%202020%20and%20July%202022.%20Severe%20COVID-19%20was%20defined%20as%20hospitalization%20or%20higher%20severity.%5CnRESULTS%3A%20Among%202584%20pwMS%20with%20confirmed%5C%2Fhighly%20suspected%20COVID-19%2C%20severe%20infection%20rates%20declined%20from%2014.6%25%20preomicron%20wave%20to%205.7%25%20during%20omicron%20wave%20%28p%5Cu2009%26lt%3B%5Cu20090.001%29.%20Multivariate%20analysis%20identified%20age%20%28odds%20ratio%20%28OR%29%5Cu2009%3D%5Cu20091.43%2C%2095%25%20confidence%20interval%20%28CI%29%5Cu2009%3D%5Cu2009%5B1.25-1.64%5D%20per%2010%5Cu2009years%29%2C%20male%20sex%20%28OR%5Cu2009%3D%5Cu20092.01%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B1.51-2.67%5D%29%2C%20obesity%20%28OR%5Cu2009%3D%5Cu20092.36%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B1.52-3.68%5D%29%2C%20cardiac%20comorbidities%20%28OR%5Cu2009%3D%5Cu20092.36%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B1.46-3.83%5D%29%2C%20higher%20Expanded%20Disability%20Status%20Scale%20%28EDSS%29%20scores%20%28OR%5Cu2009%3D%5Cu20092.09%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B1.43-3.06%5D%20for%20EDSS%203-5.5%20and%20OR%5Cu2009%3D%5Cu20094.53%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B3.04-6.75%5D%20for%20EDSS%20%5Cu2a7e6%29%2C%20and%20anti-CD20%20therapies%20%28OR%5Cu2009%3D%5Cu20092.67%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B1.85-3.87%5D%29%20as%20risk%20factors%20for%20COVID-19%20severity.%20Vaccinated%20individuals%20experienced%20less%20severe%20COVID-19%2C%20whether%20on%20%28risk%20ratio%20%28RR%29%5Cu2009%3D%5Cu20090.64%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B0.60-0.69%5D%29%20or%20off%20%28RR%5Cu2009%3D%5Cu20090.32%2C%2095%25%20CI%5Cu2009%3D%5Cu2009%5B0.30-0.33%5D%29%20anti-CD20.%5CnDISCUSSION%3A%20In%20pwMS%2C%20consistent%20risk%20factors%20were%20anti-CD20%20therapies%20and%20neurological%20disability%2C%20emerging%20as%20vital%20drivers%20of%20COVID-19%20severity%20regardless%20of%20wave%2C%20period%2C%20or%20vaccination%20status.%22%2C%22date%22%3A%222024-01-21%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1177%5C%2F13524585231218149%22%2C%22ISSN%22%3A%221477-0970%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22B4EWFM7E%22%2C%22B2M3AZVC%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A32Z%22%7D%7D%2C%7B%22key%22%3A%224BQ58R2C%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bartoli%20et%20al.%22%2C%22parsedDate%22%3A%222024-12-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBartoli%2C%20A.%2C%20Colombo%2C%20A.%2C%20Pisu%2C%20F.%2C%20Galliena%2C%20T.%2C%20Gnasso%2C%20C.%2C%20Rinaldi%2C%20E.%2C%20Melissano%2C%20G.%2C%20Palmisano%2C%20A.%2C%20%26amp%3B%20Esposito%2C%20A.%20%282024%29.%20Semiautomatic%20volume%20measure%20of%20kidney%20vascular%20territories%20on%20CT%20angiography%20to%20plan%20aortic%20aneurysm%20repair%20in%20patients%20with%20horseshoe%20kidney.%20%26lt%3Bi%26gt%3BEuropean%20Radiology%20Experimental%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B8%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20133.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs41747-024-00531-4%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs41747-024-00531-4%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Semiautomatic%20volume%20measure%20of%20kidney%20vascular%20territories%20on%20CT%20angiography%20to%20plan%20aortic%20aneurysm%20repair%20in%20patients%20with%20horseshoe%20kidney%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Axel%22%2C%22lastName%22%3A%22Bartoli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alberto%22%2C%22lastName%22%3A%22Colombo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francesco%22%2C%22lastName%22%3A%22Pisu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tommaso%22%2C%22lastName%22%3A%22Galliena%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chiara%22%2C%22lastName%22%3A%22Gnasso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Enrico%22%2C%22lastName%22%3A%22Rinaldi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Germano%22%2C%22lastName%22%3A%22Melissano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Palmisano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antonio%22%2C%22lastName%22%3A%22Esposito%22%7D%5D%2C%22abstractNote%22%3A%22Surgical%20repair%20of%20abdominal%20aortic%20aneurism%20%28AAA%29%20with%20horseshoe%20kidney%20%28HK%29%20is%20challenging%20because%20of%20several%20accessory%20renal%20arteries%20%28RAs%29%2C%20variable%20in%20number%2C%20branches%2C%20and%20vascular%20territories%2C%20with%20subsequent%20variable%20renal%20damage.%20The%20identification%20of%20RAs%20and%20vascular%20territories%20could%20contribute%20to%20surgical%20planning.%20We%20developed%20a%20semiautomatic%20presurgical%20computed%20tomography%20angiography%20%28CTA%29-based%20model%20to%20measure%20the%20renal%20volume%20of%20each%20RA%2C%20validated%20on%20postsurgical%20CTA%20in%20patients%20with%20HK%20treated%20for%20AAA.%20Renal%20parenchyma%20volume%20was%20extracted%20on%20both%20CTAs%20%28Vol_Totpre%20and%20Vol_Totpost%29%20after%20labeling%20RAs%20ostia%20and%20vascular%20endpoints%20by%20two%20observers%20using%20a%20semiautomatic%20model%20by%20assigning%20each%20renal%20voxel%20to%20the%20closest%20vascular%20ending%2C%20obtaining%20volumes%20for%20each%20vascular%20territory.%20Number%20of%20RAs%20number%20was%204.0%5Cu2009%5Cu00b1%5Cu20091.4%20%28mean%5Cu2009%5Cu00b1%5Cu2009standard%20deviation%20%28SD%29%29%2C%20Vol_Totpre%20360%5Cu2009%5Cu00b1%5Cu200976.5%5Cu2009cm3%3B%20kidney%20volume%20loss%20at%20surgery%20%28KVLS%29%20%28Vol_Totpre%20minus%20Vol_Totpost%29%2051.9%5Cu2009%5Cu00b1%5Cu200935.4%5Cu2009cm3%3B%20percentage%20of%20kidney%20loss%2015.2%5Cu2009%5Cu00b1%5Cu200911.6%25.%20KVLS%20and%20predicted%20kidney%20volume%20loss%20on%20preoperative%20CTA%20%28PKVL%29%20were%20strongly%20correlated%20%28r%5Cu2009%3D%5Cu20090.93%3B%20p%5Cu2009%3D%5Cu20090.023%29.%20Interobserver%20agreement%20was%20good%20%28mean%20bias%5Cu2009%3D%5Cu20090.000001%5Cu2009%5Cu00b1%5Cu20091.96%5Cu2009SD%20of%2019.1%5Cu2009cm3%29.%20Presurgical%20semiautomatic%20segmentation%20of%20vascular%20territories%20in%20patients%20with%20HK%20and%20AAA%20is%20feasible.%20RELEVANCE%20STATEMENT%3A%20This%20software%20allowed%20the%20preoperative%20calculation%20of%20renal%20volume%20perfused%20by%20each%20renal%20artery%20in%20the%20challenging%20association%20of%20the%20horseshoe%20kidney%20and%20abdominal%20aortic%20aneurism.%20It%20helps%5Cu00a0to%20determine%20the%20feasibility%20of%20surgical%20resection%20of%20arteries%2C%20thereby%20improving%20surgical%20planning%20and%20reducing%20the%20risk%20of%20postoperative%20renal%20function%20deterioration.%20KEY%20POINTS%3A%20The%20association%20between%20horseshoe%20kidney%20and%20abdominal%20aortic%20aneurism%20is%20a%20challenging%20condition%20that%20may%20require%20renal%20vascular%20resection.%20A%20semiautomatic%20model%20measures%20renal%20volume%20perfused%20by%20each%20artery%20on%20preoperative%20computed%20tomography%20angiography%20with%20high%20accuracy.%20Customized%20use%20of%20this%20tool%20could%20improve%20surgical%20management%20by%20determining%20which%20arteries%20can%20be%20safely%20resected%20during%20surgery.%22%2C%22date%22%3A%222024-12-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs41747-024-00531-4%22%2C%22ISSN%22%3A%222509-9280%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22CXAMISN8%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A31Z%22%7D%7D%2C%7B%22key%22%3A%226X8XQFEJ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Collongues%20et%20al.%22%2C%22parsedDate%22%3A%222024-02-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCollongues%2C%20N.%2C%20Durand-Dubief%2C%20F.%2C%20Lebrun-Frenay%2C%20C.%2C%20Audoin%2C%20B.%2C%20Ayrignac%2C%20X.%2C%20Bensa%2C%20C.%2C%20Bigaut%2C%20K.%2C%20Bourre%2C%20B.%2C%20Carra-Dalli%26%23xE8%3Bre%2C%20C.%2C%20Ciron%2C%20J.%2C%20Defer%2C%20G.%2C%20Kwiatkowski%2C%20A.%2C%20Leray%2C%20E.%2C%20Maillart%2C%20E.%2C%20Marignier%2C%20R.%2C%20Mathey%2C%20G.%2C%20Morel%2C%20N.%2C%20Thouvenot%2C%20E.%2C%20Z%26%23xE9%3Bphir%2C%20H.%2C%20%26%23x2026%3B%20Cohen%2C%20M.%20%282024%29.%20Cancer%20and%20multiple%20sclerosis%3A%202023%20recommendations%20from%20the%20French%20Multiple%20Sclerosis%20Society.%20%26lt%3Bi%26gt%3BMultiple%20Sclerosis%20%28Houndmills%2C%20Basingstoke%2C%20England%29%26lt%3B%5C%2Fi%26gt%3B%2C%2013524585231223880.%20notice.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F13524585231223880%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1177%5C%2F13524585231223880%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cancer%20and%20multiple%20sclerosis%3A%202023%20recommendations%20from%20the%20French%20Multiple%20Sclerosis%20Society%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Collongues%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fran%5Cu00e7oise%22%2C%22lastName%22%3A%22Durand-Dubief%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Lebrun-Frenay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Audoin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xavier%22%2C%22lastName%22%3A%22Ayrignac%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Bensa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K%5Cu00e9vin%22%2C%22lastName%22%3A%22Bigaut%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bertrand%22%2C%22lastName%22%3A%22Bourre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clarisse%22%2C%22lastName%22%3A%22Carra-Dalli%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%22%2C%22lastName%22%3A%22Ciron%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gilles%22%2C%22lastName%22%3A%22Defer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arnaud%22%2C%22lastName%22%3A%22Kwiatkowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Emmanuelle%22%2C%22lastName%22%3A%22Leray%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Maillart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Romain%22%2C%22lastName%22%3A%22Marignier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Guillaume%22%2C%22lastName%22%3A%22Mathey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nathalie%22%2C%22lastName%22%3A%22Morel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22Thouvenot%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H%5Cu00e9l%5Cu00e8ne%22%2C%22lastName%22%3A%22Z%5Cu00e9phir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julie%22%2C%22lastName%22%3A%22Boucher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cl%5Cu00e9mence%22%2C%22lastName%22%3A%22Bouti%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pierre%22%2C%22lastName%22%3A%22Branger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ang%5Cu00e9lique%22%2C%22lastName%22%3A%22Da%20Silva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Demorti%5Cu00e8re%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maxime%22%2C%22lastName%22%3A%22Guillaume%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%22%2C%22lastName%22%3A%22Hebant%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Edouard%22%2C%22lastName%22%3A%22Januel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Kerbrat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22Manchon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xavier%22%2C%22lastName%22%3A%22Moisset%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexis%22%2C%22lastName%22%3A%22Montcuquet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chlo%5Cu00e9%22%2C%22lastName%22%3A%22Pierret%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julie%22%2C%22lastName%22%3A%22Pique%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julien%22%2C%22lastName%22%3A%22Poupart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chlo%5Cu00e9%22%2C%22lastName%22%3A%22Prunis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Roux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Perrine%22%2C%22lastName%22%3A%22Schmitt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G%5Cu00e9raldine%22%2C%22lastName%22%3A%22Androdias%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mikael%22%2C%22lastName%22%3A%22Cohen%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Epidemiological%20data%20reveal%20that%2045%25%20of%20persons%20with%20multiple%20sclerosis%20%28PwMS%29%20in%20France%20are%20more%20than%2050%5Cu2009years.%20This%20population%20more%20than%2050%20is%20more%20susceptible%20to%20cancer%2C%20and%20this%20risk%20may%20be%20increased%20by%20frequent%20use%20of%20immunosuppressive%20drugs.%20Consequently%2C%20concerns%20have%20arisen%20about%20the%20potential%20increased%20risk%20of%20cancer%20in%20PwMS%20and%20how%20patients%20should%20be%20screened%20and%20managed%20in%20terms%20of%20cancer%20risk.%5CnOBJECTIVE%3A%20To%20develop%20evidence-based%20recommendations%20to%20manage%20the%20coexistence%20of%20cancer%20and%20multiple%20sclerosis%20%28MS%29.%5CnMETHODS%3A%20The%20French%20Group%20for%20Recommendations%20in%20MS%20collected%20articles%20from%20PubMed%20and%20university%20databases%20covering%20the%20period%20January%201975%20through%20June%202022.%20The%20RAND%5C%2FUCLA%20method%20was%20employed%20to%20achieve%20formal%20consensus.%20MS%20experts%20comprehensively%20reviewed%20the%20full-text%20articles%20and%20developed%20the%20initial%20recommendations.%20A%20group%20of%20multidisciplinary%20health%20care%20specialists%20then%20validated%20the%20final%20proposal.%5CnRESULTS%3A%20Five%20key%20questions%20were%20addressed%2C%20encompassing%20various%20topics%20such%20as%20cancer%20screening%20before%20or%20after%20initiating%20a%20disease-modifying%20therapy%20%28DMT%29%2C%20appropriate%20management%20of%20MS%20in%20the%20context%20of%20cancer%2C%20recommended%20follow-up%20for%20cancer%20in%20patients%20receiving%20a%20DMT%2C%20and%20the%20potential%20reintroduction%20of%20a%20DMT%20after%20initial%20cancer%20treatment.%20A%20strong%20consensus%20was%20reached%20for%20all%2031%20recommendations.%5CnCONCLUSION%3A%20These%20recommendations%20propose%20a%20strategic%20approach%20to%20managing%20cancer%20risk%20in%20PwMS.%22%2C%22date%22%3A%222024-02-15%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1177%5C%2F13524585231223880%22%2C%22ISSN%22%3A%221477-0970%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%226KPLZTET%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22YFPNBYRC%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bernard%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBernard%2C%20M.%20%282024%29.%20Editorial%20for%20%26%23x201C%3BPulmonary%20Transit%20Time%20Derived%20from%20First-Pass%20Perfusion%20Cardiac%20MR%20Imaging%3A%20A%20Potential%20New%20Marker%20for%20Cardiac%20Involvement%20and%20Prognosis%20in%20Light-Chain%20Amyloidosis.%26%23x201D%3B%20%26lt%3Bi%26gt%3BJournal%20of%20Magnetic%20Resonance%20Imaging%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B60%26lt%3B%5C%2Fi%26gt%3B%283%29%2C%201011%26%23x2013%3B1012.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fjmri.29136%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fjmri.29136%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Editorial%20for%20%5Cu201cPulmonary%20Transit%20Time%20Derived%20from%20First-Pass%20Perfusion%20Cardiac%20MR%20Imaging%3A%20A%20Potential%20New%20Marker%20for%20Cardiac%20Involvement%20and%20Prognosis%20in%20Light-Chain%20Amyloidosis%5Cu201d%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Monique%22%2C%22lastName%22%3A%22Bernard%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fjmri.29136%22%2C%22ISSN%22%3A%221522-2586%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Fjmri.29136%22%2C%22collections%22%3A%5B%225Z6CVJGB%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A30Z%22%7D%7D%2C%7B%22key%22%3A%22URK7LBWQ%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kober%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BKober%2C%20F.%2C%20Caus%2C%20T.%2C%20Riberi%2C%20A.%2C%20Le%20Fur%2C%20Y.%2C%20%26amp%3B%20Bernard%2C%20M.%20%282024%29.%20Time%20Course%20of%20High-Energy%20Phosphate%20Depletion%20During%20Cold%20Storage%20of%20Human%20Heart%20Grafts%20Using%20the%20Celsior%20Solution.%20%26lt%3Bi%26gt%3BTransplant%20International%3A%20Official%20Journal%20of%20the%20European%20Society%20for%20Organ%20Transplantation%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B37%26lt%3B%5C%2Fi%26gt%3B%2C%2012994.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Fti.2024.12994%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Fti.2024.12994%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Time%20Course%20of%20High-Energy%20Phosphate%20Depletion%20During%20Cold%20Storage%20of%20Human%20Heart%20Grafts%20Using%20the%20Celsior%20Solution%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frank%22%2C%22lastName%22%3A%22Kober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thierry%22%2C%22lastName%22%3A%22Caus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alberto%22%2C%22lastName%22%3A%22Riberi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yann%22%2C%22lastName%22%3A%22Le%20Fur%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Monique%22%2C%22lastName%22%3A%22Bernard%22%7D%5D%2C%22abstractNote%22%3A%22The%20aim%20of%20this%20study%20was%20to%20provide%20insight%20into%20high-energy%20phosphate%20compound%20concentration%20dynamics%20under%20realistic%20clinical%20cold-storage%20conditions%20using%20the%20Celsior%20solution%20in%20seven%20heart%20grafts%20discarded%20from%20transplantation.%20The%20hearts%20of%20seven%20local%20donors%20%28three%20males%2C%20four%20females%2C%20age%2037%20%5Cu00b1%2017%5Cu00a0years%2C%20height%20175%20%5Cu00b1%205%5Cu00a0cm%2C%20weight%2075%20%5Cu00b1%209%5Cu00a0kg%29%20initially%20considered%20for%20transplantation%20and%20eventually%20discarded%20were%20submitted%20to%20a%20Magnetic%20Resonance%20Spectroscopy%20observation%20in%20a%20clinical%20Magnetic%20Resonance%20Imaging%20scanner%20over%20at%20least%209%5Cu00a0h.%20The%20grafts%20remained%20in%20their%20sterile%20container%20at%204%5Cu00b0C%20during%20the%20entire%20examination.%20Hence%2C%20Phosphocreatine%20%28PCr%29%2C%20adenosine%20triphosphate%20%28ATP%29%2C%20inorganic%20phosphate%20%28Pi%29%20and%20intracellular%20pH%20were%20recorded%20non-destructively%20at%20a%2030-minute%20interval.%20With%20the%20ischemic%20time%20Ti%2C%20the%20concentration%20ratios%20decreased%20at%20PCr%5C%2FATP%20%3D%201.68-0.0028%5Cu00b7Tis%2C%20Pi%5C%2FATP%20%3D%201.38%20%2B%200.0029%5Cu00b7Tis%2C%20and%20intracellular%20pH%20at%207.43-0.0012%5Cu00b7Tis.%20ATP%20concentration%20remained%20stable%20for%20at%20least%209%5Cu00a0h%20and%20did%20not%20decrease%20as%20long%20as%20phosphocreatine%20was%20detectable.%20Acidosis%20remained%20moderate.%20In%20addition%20to%20the%20standard%20parameters%20assessed%20at%20the%20time%20of%20retrieval%2C%20Magnetic%20Resonance%20Spectroscopy%20can%20provide%20an%20assesment%20of%20the%20metabolic%20status%20of%20heart%20grafts%20before%20transplantation.%20These%20results%20show%20how%20HEPC%20metabolites%20deplete%20during%20cold%20storage.%20Although%20many%20parameters%20determine%20graft%20quality%20during%20cold%20storage%2C%20the%20dynamics%20of%20HEPC%20and%20intracellular%20pH%20may%20be%20helpful%20in%20the%20development%20of%20strategies%20aiming%20at%20extending%20the%20ischemic%20time.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3389%5C%2Fti.2024.12994%22%2C%22ISSN%22%3A%221432-2277%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%225Z6CVJGB%22%2C%22BR9D2SS4%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A29Z%22%7D%7D%2C%7B%22key%22%3A%22TM953QIS%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bo%5Cu017ei%5Cu0107-Iven%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBo%26%23x17E%3Bi%26%23x107%3B-Iven%2C%20M.%2C%20Rapacchi%2C%20S.%2C%20Tao%2C%20Q.%2C%20Pierce%2C%20I.%2C%20Thornton%2C%20G.%2C%20Nitsche%2C%20C.%2C%20Treibel%2C%20T.%20A.%2C%20Schad%2C%20L.%20R.%2C%20%26amp%3B%20Weing%26%23xE4%3Brtner%2C%20S.%20%282024%29.%20Improved%20reproducibility%20for%20myocardial%20ASL%3A%20Impact%20of%20physiological%20and%20acquisition%20parameters.%20%26lt%3Bi%26gt%3BMagnetic%20Resonance%20in%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B91%26lt%3B%5C%2Fi%26gt%3B%281%29%2C%20118%26%23x2013%3B132.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.29834%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fmrm.29834%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Improved%20reproducibility%20for%20myocardial%20ASL%3A%20Impact%20of%20physiological%20and%20acquisition%20parameters%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ma%5Cu0161a%22%2C%22lastName%22%3A%22Bo%5Cu017ei%5Cu0107-Iven%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stanislas%22%2C%22lastName%22%3A%22Rapacchi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qian%22%2C%22lastName%22%3A%22Tao%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Iain%22%2C%22lastName%22%3A%22Pierce%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22George%22%2C%22lastName%22%3A%22Thornton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Nitsche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%20A.%22%2C%22lastName%22%3A%22Treibel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lothar%20R.%22%2C%22lastName%22%3A%22Schad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sebastian%22%2C%22lastName%22%3A%22Weing%5Cu00e4rtner%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20To%20investigate%20and%20mitigate%20the%20influence%20of%20physiological%20and%20acquisition-related%20parameters%20on%20myocardial%20blood%20flow%20%28MBF%29%20measurements%20obtained%20with%20myocardial%20Arterial%20Spin%20Labeling%20%28myoASL%29.%20Methods%20A%20Flow-sensitive%20Alternating%20Inversion%20Recovery%20%28FAIR%29%20myoASL%20sequence%20with%20bSSFP%20and%20spoiled%20GRE%20%28spGRE%29%20readout%20is%20investigated%20for%20MBF%20quantification.%20Bloch-equation%20simulations%20and%20phantom%20experiments%20were%20performed%20to%20evaluate%20how%20variations%20in%20acquisition%20flip%20angle%20%28FA%29%2C%20acquisition%20matrix%20size%20%28AMS%29%2C%20heart%20rate%20%28HR%29%20and%20blood%20T1%5C%5C%20%5C%5CmathrmT_1%20%5C%5C%20relaxation%20time%20%28T1%2CB%5C%5C%20%5C%5CmathrmT_1%2CB%20%5C%5C%29%20affect%20quantification%20of%20myoASL-MBF.%20In%20vivo%20myoASL-images%20were%20acquired%20in%20nine%20healthy%20subjects.%20A%20corrected%20MBF%20quantification%20approach%20was%20proposed%20based%20on%20subject-specific%20T1%2CB%5C%5C%20%5C%5CmathrmT_1%2CB%20%5C%5C%20values%20and%2C%20for%20spGRE%20imaging%2C%20subtracting%20an%20additional%20saturation-prepared%20baseline%20from%20the%20original%20baseline%20signal.%20Results%20Simulated%20and%20phantom%20experiments%20showed%20a%20strong%20dependence%20on%20AMS%20and%20FA%20%28R2%5C%5C%20R%5E2%20%5C%5C%26gt%3B0.73%29%2C%20which%20was%20eliminated%20in%20simulations%20and%20alleviated%20in%20phantom%20experiments%20using%20the%20proposed%20saturation-baseline%20correction%20in%20spGRE.%20Only%20a%20very%20mild%20HR%20dependence%20%28R2%5C%5C%20R%5E2%20%5C%5C%26gt%3B0.59%29%20was%20observed%20which%20was%20reduced%20when%20calculating%20MBF%20with%20individual%20T1%2CB%5C%5C%20%5C%5CmathrmT_1%2CB%20%5C%5C.%20For%20corrected%20spGRE%2C%20in%20vivo%20mean%20global%20spGRE-MBF%20ranged%20from%200.54%20to%202.59%20mL%5C%2Fg%5C%2Fmin%20and%20was%20in%20agreement%20with%20previously%20reported%20values.%20Compared%20to%20uncorrected%20spGRE%2C%20the%20intra-subject%20variability%20within%20a%20measurement%20%280.60%20mL%5C%2Fg%5C%2Fmin%29%2C%20between%20measurements%20%280.45%20mL%5C%2Fg%5C%2Fmin%29%2C%20as%20well%20as%20the%20inter-subject%20variability%20%281.29%20mL%5C%2Fg%5C%2Fmin%29%20were%20improved%20by%20up%20to%2040%25%20and%20were%20comparable%20with%20conventional%20bSSFP.%20Conclusion%20Our%20results%20show%20that%20physiological%20and%20acquisition-related%20factors%20can%20lead%20to%20spurious%20changes%20in%20myoASL-MBF%20if%20not%20accounted%20for.%20Using%20individual%20T1%2CB%5C%5C%20%5C%5CmathrmT_1%2CB%20%5C%5C%20and%20a%20saturation-baseline%20can%20reduce%20these%20variations%20in%20spGRE%20and%20improve%20reproducibility%20of%20FAIR-myoASL%20against%20acquisition%20parameters.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fmrm.29834%22%2C%22ISSN%22%3A%221522-2594%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Fmrm.29834%22%2C%22collections%22%3A%5B%22SK6VWU7K%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A29Z%22%7D%7D%2C%7B%22key%22%3A%22ERTGNHM7%22%2C%22library%22%3A%7B%22id%22%3A180164%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Cadour%20et%20al.%22%2C%22parsedDate%22%3A%222024-04-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BCadour%2C%20F.%2C%20Cour%2C%20A.%2C%20Senlis%2C%20J.%2C%20Rapacchi%2C%20S.%2C%20Chennoufi%2C%20H.%2C%20Michelin%2C%20P.%2C%20McQuade%2C%20C.%2C%20Demeyere%2C%20M.%2C%20%26amp%3B%20Dacher%2C%20J.-N.%20%282024%29.%20How%20to%20use%20MRI%20in%20cardiac%20disease%20with%20diastolic%20dysfunction%3F%20%26lt%3Bi%26gt%3BThe%20British%20Journal%20of%20Radiology%26lt%3B%5C%2Fi%26gt%3B%2C%20tqae071.%20file.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbjr%5C%2Ftqae071%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1093%5C%2Fbjr%5C%2Ftqae071%26lt%3B%5C%2Fa%26gt%3B%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22How%20to%20use%20MRI%20in%20cardiac%20disease%20with%20diastolic%20dysfunction%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Farah%22%2C%22lastName%22%3A%22Cadour%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adrien%22%2C%22lastName%22%3A%22Cour%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jules%22%2C%22lastName%22%3A%22Senlis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stanislas%22%2C%22lastName%22%3A%22Rapacchi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hajer%22%2C%22lastName%22%3A%22Chennoufi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%22%2C%22lastName%22%3A%22Michelin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Colin%22%2C%22lastName%22%3A%22McQuade%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthieu%22%2C%22lastName%22%3A%22Demeyere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Nicolas%22%2C%22lastName%22%3A%22Dacher%22%7D%5D%2C%22abstractNote%22%3A%22Left%20ventricular%20%28LV%29%20diastolic%20dysfunction%20%28DD%29%20is%20an%20initially%20asymptomatic%20condition%20that%20can%20progress%20to%20heart%20failure%2C%20either%20with%20preserved%20or%20reduced%20ejection%20fraction.%20As%20such%2C%20DD%20is%20a%20growing%20public%20health%20problem.%20Impaired%20relaxation%2C%20the%20first%20stage%20of%20DD%2C%20is%20associated%20with%20altered%20LV%20filling.%20With%20progression%2C%20reducing%20LV%20compliance%20leads%20to%20restrictive%20cardiomyopathy.%20While%20cardiac%20magnetic%20resonance%20%28CMR%29%20imaging%20is%20the%20reference%20for%20LV%20systolic%20function%20assessment%2C%20transthoracic%20echocardiography%20%28TTE%29%20with%20Doppler%20flow%20measurements%20remains%20the%20standard%20for%20diastolic%20function%20assessment.%20Rather%20than%20simply%20replicating%20TTE%20measurements%2C%20CMR%20should%20complement%20and%20further%20advance%20TTE%20findings.%20We%20provide%20herein%20a%20step-by-step%20review%20of%20CMR%20findings%20in%20DD%20as%20well%20as%20imaging%20features%20which%20may%20help%20to%20identify%20the%20underlying%20cause.%22%2C%22date%22%3A%222024-04-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1093%5C%2Fbjr%5C%2Ftqae071%22%2C%22ISSN%22%3A%221748-880X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22SK6VWU7K%22%5D%2C%22dateModified%22%3A%222025-09-12T07%3A59%3A28Z%22%7D%7D%5D%7D
Kober, F., Caus, T., Riberi, A., Confort-Gouny, S., LeFur, Y., Izquierdo, M., Ranjeva, J.-P., Viout, P., Mesana, T., Metras, D., Cozzone, P. J., & Bernard, M. (2002). Objective and noninvasive metabolic characterization of donor hearts by phosphorous-31 magnetic resonance spectroscopy. Transplantation, 74(12), 1752–1756. notice. https://doi.org/https://doi.org/10.1097/00007890-200212270-00018
Melka, M., Rotard, L., Benstaali, C., Brocard, J., Giannesini, B., Jouve, F., Pelletier, L., Fauré, J., Rendu, J., Jacquemond, V., & Marty, I. (2025). Limited pre-clinical relevance of the heterozygous RYR1-I4895T/+ mouse model due to its mild phenotype. Journal of Neuromuscular Diseases, 22143602251339354. https://doi.org/10.1177/22143602251339354
Brun, G., Testud, B., Girard, O. M., Lehmann, P., de Rochefort, L., Besson, P., Massire, A., Ridley, B., Girard, N., Guye, M., Ranjeva, J.-P., & Le Troter, A. (2022). Automatic segmentation of deep grey nuclei using a high-resolution 7T magnetic resonance imaging atlas—Quantification of T1 values in healthy volunteers. European Journal of Neuroscience, 55(2), 438–460. file. https://doi.org/10.1111/ejn.15575
Haast, R. A. M., Testud, B., Makhalova, J., Dary, H., Cabane, A., Le Troter, A., Ranjeva, J.-P., Bartolomei, F., & Guye, M. (2023). Multi-scale structural alterations of the thalamus and basal ganglia in focal epilepsy using 7T MRI. Human Brain Mapping, 44(13), 4754–4771. file. https://doi.org/10.1002/hbm.26414
Thiery, L., Carle, X., Testud, B., Boulouis, G., Habert, P., Tradi, F., Reyre, A., Lehmann, P., Dory-Lautrec, P., Stellmann, J.-P., Girard, N., Brunel, H., & Hak, J.-F. (2023). Distal cerebral vasospasm treatment following aneurysmal subarachnoid hemorrhage using the Comaneci device: technical feasibility and single-center preliminary results. Journal of NeuroInterventional Surgery, 15(4), 325–329. notice. https://doi.org/10.1136/neurintsurg-2022-018699
Testud, B., Brun, G., Varoquaux, A., Hak, J. F., Appay, R., Le Troter, A., Girard, N., & Stellmann, J. P. (2021). Perfusion-weighted techniques in MRI grading of pediatric cerebral tumors: efficiency of dynamic susceptibility contrast and arterial spin labeling. Neuroradiology, 63(8), 1353–1366. notice. https://doi.org/10.1007/s00234-021-02640-y
Testud, B., Fabiani, N., Demortière, S., Mchinda, S., Medina, N. L., Pelletier, J., Guye, M., Audoin, B., Stellmann, J. P., & Callot, V. (2023). Contribution of the MP2RAGE 7T Sequence in MS Lesions of the Cervical Spinal Cord. AJNR. American Journal of Neuroradiology, 44(9), 1101–1107. file. https://doi.org/10.3174/ajnr.A7964
Testud, B., Stellmann, J.-P., Girard, N., & Hak, J.-F. (2022). Tumoral Hemorrhagic Stroke Revealing Carotid Angiosarcoma-Related Cerebral Metastases. Neurology India, 70(5), 2246–2248. notice. https://doi.org/10.4103/0028-3886.359227
Testud, B., Brun, G., Kaphan, E., Stellmann, J. P., Girard, N., & Hak, J.-F. (2021). Distinctive MRI features of paraneoplastic encephalitis with anti-Ri antibodies. Revue Neurologique, 177(3), 315–317. notice. https://doi.org/10.1016/j.neurol.2020.05.009
Testud, B., Delacour, C., El Ahmadi, A. A., Brun, G., Girard, N., Duhamel, G., Heesen, C., Häußler, V., Thaler, C., Has Silemek, A. C., & Stellmann, J.-P. (2022). Brain grey matter perfusion in primary progressive multiple sclerosis: Mild decrease over years and regional associations with cognition and hand function. European Journal of Neurology, 29(6), 1741–1752. file. https://doi.org/10.1111/ene.15289
Drai, M., Testud, B., Brun, G., Hak, J.-F., Scavarda, D., Girard, N., & Stellmann, J.-P. (2022). Borrowing strength from adults: Transferability of AI algorithms for paediatric brain and tumour segmentation. European Journal of Radiology, 151, 110291. file. https://doi.org/10.1016/j.ejrad.2022.110291
Tilsley, P., Moutiez, A., Brodovitch, A., Mendili, M. M. E., Testud, B., Zaaraoui, W., Verschueren, A., Attarian, S., Guye, M., Boucraut, J., Grapperon, A.-M., & Stellmann, J.-P. (2024). Neurofilament Light Chain Levels Interact with Neurodegenerative Patterns and Motor Neuron Dysfunction in Amyotrophic Lateral Sclerosis. American Journal of Neuroradiology, 45(4), 494–503. notice. https://doi.org/10.3174/ajnr.A8154
Bastiancich, C., Snacel-Fazy, E., Fernandez, S., Robert, S., Stacchini, R., Plantureux, L., Boissonneau, S., Testud, B., Guillet, B., Debarbieux, F., Luche, H., Figarella-Branger, D., Estève, M.-A., Tabouret, E., & Tchoghandjian, A. (2024). Tailoring glioblastoma treatment based on longitudinal analysis of post-surgical tumor microenvironment. Journal of Experimental & Clinical Cancer Research: CR, 43(1), 311. file. https://doi.org/10.1186/s13046-024-03231-4
Harlay, V., Campello, C., Bequet, C., Petrirena, G., Barrie, M., Appay, R., Arnoux, I., Loosveld, M., Testud, B., Bertucci, A., Tabouret, E., & Chinot, O. (2024). Primary central nervous system lymphoma with initial spinal cord involvement (PCNSL-SC) is a rare entity: 4 case reports and review of literature. Revue Neurologique, 180(3), 224–229. notice. https://doi.org/10.1016/j.neurol.2023.10.003
Testud, B., Carle, X., Costes, C., Hak, J.-F., & Guye, M. (2024). Added Value of Ultrahigh-Resolution 7T MRI in Dural Arteriovenous Fistulas. Stroke, 55(3), e46–e47. file. https://doi.org/10.1161/STROKEAHA.123.045930
Testud, B., Guye, M., Witjas, T., & Grimaldi, S. (2024). Iron overload revealing the cytoarchitecture of the red nucleus: A case study. Revue Neurologique, S0035-3787(24)00660-X. file. https://doi.org/10.1016/j.neurol.2024.11.001
Aita, J.-F., Agripnidis, T., Testud, B., Barral, P.-A., Jacquier, A., Reyre, A., Alnuaimi, A., Girard, N., Tradi, F., Habert, P., Gariboldi, V., Collart, F., Bartoli, A., & Hak, J.-F. (2022). Stenting in Brain Hemodynamic Injury of Carotid Origin Caused by Type A Aortic Dissection: Local Experience and Systematic Literature Review. Journal of Personalized Medicine, 13(1), 58. file. https://doi.org/10.3390/jpm13010058
Joppin, V., Jourdan, A., Bendahan, D., Soucasse, A., Guye, M., Masson, C., & Bège, T. (2024). Towards a better understanding of abdominal wall biomechanics: In vivo relationship between dynamic intra-abdominal pressure and magnetic resonance imaging measurements. Clinical Biomechanics (Bristol, Avon), 121, 106396. file. https://doi.org/10.1016/j.clinbiomech.2024.106396
Sole Cruz, E., Stolowy, N., Attia, R., Audoin, B., & Demortière, S. (2024). Acute posterior ischemic optic neuropathy associated with a hypertensive crisis. Revue Neurologique, 180(3), 218–219. notice. https://doi.org/10.1016/j.neurol.2023.12.002
Cruz, E. S., Fortanier, E., Hilezian, F., Maarouf, A., Boutière, C., Demortière, S., Rico, A., Delmont, E., Pelletier, J., Attarian, S., & Audoin, B. (2024). Factors affecting the topography of nitrous oxide-induced neurological complications. European Journal of Neurology, e16291. file. https://doi.org/10.1111/ene.16291
Cruz, E. S., Fortanier, E., Michel, C. P., Delmont, E., Verschueren, A., Hostin, M.-A., Bendahan, D., & Attarian, S. (2025). Intraepineurial Fat Fraction: A Novel MR Neurography-Based Biomarker in Transthyretin Amyloidosis Polyneuropathy. European Journal of Neurology, 32(4). pubmedcentral. https://doi.org/10.1111/ene.70168
Demortiere, S., Stolowy, N., Perriguey, M., Boutiere, C., Rico, A., Hilezian, F., Ndjomo-Ndjomo, B.-R., Durozard, P., Stellmann, J.-P., Marignier, R., Boucraut, J., Pelletier, J., Maarouf, A., & Audoin, B. (2025). Diagnostic Utility of Kappa Free Light Chain Index in Adults With Inaugural Optic Neuritis. Neurology(R) Neuroimmunology & Neuroinflammation, 12(3), e200386. file. https://doi.org/10.1212/NXI.0000000000200386
Joppin, V., Masson, C., Bendahan, D., & Bege, T. (2025). A review of ventral hernia biomechanics. Journal of the Mechanical Behavior of Biomedical Materials, 173, 107159. https://doi.org/10.1016/j.jmbbm.2025.107159
Agripnidis, T., Ayobi, A., Quenet, S., Chaibi, Y., Avare, C., Jacquier, A., Girard, N., Hak, J.-F., Reyre, A., Brun, G., & El Ahmadi, A.-A. (2025). Performance of an artificial intelligence tool for multi-step acute stroke imaging: A multicenter diagnostic study. European Journal of Radiology Open, 15, 100678. https://doi.org/10.1016/j.ejro.2025.100678
Porto, A., Court, A., Barral, P. A., Boucekine, M., Imbert, L., Gariboldi, V., Jacquier, A., Collart, F., Theron, A., & Gaudry, M. (2025). Evolution of Aortic Root Preservation After Type A Acute Aortic Dissection Repair: Impact of Root-Residual Aortic Dissection. Journal of Clinical Medicine, 14(17), 6274. https://doi.org/10.3390/jcm14176274
Jougleux, C., Joly, H., Brissard, H., Lenne, B., François, S., Hamelin, F., Derache, N., Morin, J., Reuter, F., Colamarino, R., & Ruet, A. (2024). French consensus procedure for neuropsychological assessment in multiple sclerosis. Revue Neurologique, S0035-3787(24)00558-7. notice. https://doi.org/10.1016/j.neurol.2024.06.005
Pinto, J., McGee, A., Mattern, H., Markenroth Bloch, K., Haast, R. A. M., Küstner, T., & Vannesjo, S. J. (2024). ESMRMB 2024 focus topic “MR Beyond Structures: The dynamic body at different scales.” Magnetic Resonance Materials in Physics, Biology and Medicine, 37(3), 319–319. file. https://doi.org/10.1007/s10334-024-01175-6
Chakraborty, S., Lee, S. K., Arnold, S. M., Haast, R. A. M., Khan, A. R., & Schmitz, T. W. (2024). Focal acetylcholinergic modulation of the human midcingulo-insular network during attention: Meta-analytic neuroimaging and behavioral evidence. Journal of Neurochemistry, 168(4), 397–413. openaccess. https://doi.org/10.1111/jnc.15990
Chakraborty, S., Haast, R. A. M., Onuska, K. M., Kanel, P., Prado, M. A. M., Prado, V. F., Khan, A. R., & Schmitz, T. W. (2024). Multimodal gradients of basal forebrain connectivity across the neocortex. Nature Communications, 15(1), 8990. file. https://doi.org/10.1038/s41467-024-53148-x
Bolton, T. A. W., Van De Ville, D., Régis, J., Witjas, T., Girard, N., Levivier, M., & Tuleasca, C. (2024). Dynamic functional changes upon thalamotomy in essential tremor depend on baseline brain morphometry. Scientific Reports, 14(1), 2605. file. https://doi.org/10.1038/s41598-024-52410-y
Venet, M., Lepine, A., Maarouf, A., Biotti, D., Boutiere, C., Casez, O., Cohen, M., Durozard, P., Demortière, S., Giorgi, L., Maillart, E., Mathey, G., Mazzola, L., Rico, A., Camdessanche, J.-P., Deiva, K., Pelletier, J., & Audoin, B. (2024). Control of disease activity with large extended-interval dosing of rituximab/ocrelizumab in highly active pediatric multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 13524585231223069. notice. https://doi.org/10.1177/13524585231223069
Castelli, M., Maurin, A., Bartoli, A., Dassa, M., Marchi, B., Finance, J., Lagier, J.-C., Million, M., Parola, P., Brouqui, P., Raoult, D., Cortaredona, S., Jacquier, A., Gaubert, J.-Y., & Habert, P. (2024). Author Correction: Prevalence and risk factors for lung involvement on low-dose chest CT (LDCT) in a paucisymptomatic population of 247 patients affected by COVID-19. Insights into Imaging, 15(1), 266. openaccess. https://doi.org/10.1186/s13244-024-01847-w
Macchi, R., Kunimasa, Y., Chavet, P., Corcelle, B., Pomportes, L., Fazzari, C., Hays, A., Vercruyssen, F., Rossi, F., Bendahan, D., & Nicol, C. (2024). Effect of a graded running race on lower limb muscle damage, jump performance and muscle soreness in men and women. Scandinavian Journal of Medicine & Science in Sports, 34(5), e14643. file. https://doi.org/10.1111/sms.14643
Matias, A. A., Serviente, C. F., Decker, S. T., Erol, M. E., Giuriato, G., Le Fur, Y., Nagarajan, R., Bendahan, D., & Layec, G. (2024). Repeatability of alkaline inorganic phosphate quantification in the skeletal muscle using 31P-magnetic resonance spectroscopy at 3 T. NMR in Biomedicine, e5255. file. https://doi.org/10.1002/nbm.5255
Sallustio, V., Rossi, M., Mandrone, M., Rossi, F., Chiocchio, I., Cerchiara, T., Longo, E., Fratini, M., D’Amico, L., Tromba, G., Malucelli, E., Protti, M., Mercolini, L., Di Blasio, A., Aponte, M., Blaiotta, G., Abruzzo, A., Bigucci, F., Luppi, B., & Cappadone, C. (2024). A promising eco-sustainable wound dressing based on cellulose extracted from Spartium junceum L. and impregnated with Glycyrrhiza glabra L extract: Design, production and biological properties. International Journal of Biological Macromolecules, 272(Pt 2), 132883. file. https://doi.org/10.1016/j.ijbiomac.2024.132883
Aung, N., Bartoli, A., Rauseo, E., Cortaredona, S., Sanghvi, M. M., Fournel, J., Ghattas, B., Khanji, M. Y., Petersen, S. E., & Jacquier, A. (2024). Left Ventricular Trabeculations at Cardiac MRI: Reference Ranges and Association with Cardiovascular Risk Factors in UK Biobank. Radiology, 311(1), e232455. file. https://doi.org/10.1148/radiol.232455
Licht, C., Reichert, S., Bydder, M., Zapp, J., Corella, S., Guye, M., Zöllner, F. G., Schad, L. R., & Rapacchi, S. (2024). Low-rank reconstruction for simultaneous double half-echo 23Na and undersampled 23Na multi-quantum coherences MRI. Magnetic Resonance in Medicine, 92(4), 1440–1455. file. https://doi.org/10.1002/mrm.30132
Licht, C., Reichert, S., Guye, M., Schad, L. R., & Rapacchi, S. (2024). Multidimensional compressed sensing to advance 23Na multi-quantum coherences MRI. Magnetic Resonance in Medicine, 91(3), 926–941. file. https://doi.org/10.1002/mrm.29902
Brui, E. A., Badrieva, Z., de Mayenne, C.-A., Rapacchi, S., Troalen, T., & Bendahan, D. (2024). Mitigating slice cross-talk in multi-slice multi-echo spin echo T2 mapping. Magnetic Resonance in Medicine, 91(5), 2089–2103. notice. https://doi.org/10.1002/mrm.29987
Androdias, G., Lünemann, J. D., Maillart, E., Amato, M. P., Audoin, B., Bruijstens, A. L., Bsteh, G., Butzkueven, H., Ciccarelli, O., Cobo-Calvo, A., Derfuss, T., Di Pauli, F., Edan, G., Enzinger, C., Geraldes, R., Granziera, C., Hacohen, Y., Hartung, H.-P., Hynes, S., … Stankoff, B. (2024). De-escalating and discontinuing disease-modifying therapies in multiple sclerosis. Brain, awae409. notice. https://doi.org/10.1093/brain/awae409
Varoquaux, A., Fakhry, N., Scemama, U., & Taïeb, D. (2024). Differentiation of vagal from carotid paraganglioma on unenhanced PET/CT: the “sweet potato” shape on PET. European Journal of Nuclear Medicine and Molecular Imaging, 51(12), 3799–3801. notice. https://doi.org/10.1007/s00259-024-06776-w
Monestier, L., Del Grande, J., Haddad, R., Santini, L., Michel, J., Varoquaux, A., & Fakhry, N. (2024). Correlation between MRI (DWI and DCE) and cellularity of parotid gland pleomorphic adenomas. European Archives of Oto-Rhino-Laryngology, 281(5), 2655–2665. notice. https://doi.org/10.1007/s00405-024-08562-8
Omouri, A., Rapacchi, S., Duclos, J., Niddam, R., Bellemare, M.-E., & Pirró, N. (2024). 3D Observation of Pelvic Organs with Dynamic MRI Segmentation: A Bridge Toward Patient-Specific Models. International Urogynecology Journal, 35(7), 1389–1397. file. https://doi.org/10.1007/s00192-024-05817-0
Jeantin, L., Januel, E., Labauge, P., Maillart, E., de Seze, J., Zéphir, H., Pelletier, J., Kerschen, P., Biotti, D., Heinzlef, O., Guilloton, L., Bensa, C., Théaudin, M., Vukusic, S., Casez, O., Maurousset, A., Laplaud, D., Berger, E., Lebrun-Frenay, C., … Louapre, C. (2024). COVID-19 outcomes in patients with multiple sclerosis: Understanding changes from 2020 to 2022. Multiple Sclerosis (Houndmills, Basingstoke, England), 13524585231218149. file. https://doi.org/10.1177/13524585231218149
Bartoli, A., Colombo, A., Pisu, F., Galliena, T., Gnasso, C., Rinaldi, E., Melissano, G., Palmisano, A., & Esposito, A. (2024). Semiautomatic volume measure of kidney vascular territories on CT angiography to plan aortic aneurysm repair in patients with horseshoe kidney. European Radiology Experimental, 8(1), 133. file. https://doi.org/10.1186/s41747-024-00531-4
Collongues, N., Durand-Dubief, F., Lebrun-Frenay, C., Audoin, B., Ayrignac, X., Bensa, C., Bigaut, K., Bourre, B., Carra-Dallière, C., Ciron, J., Defer, G., Kwiatkowski, A., Leray, E., Maillart, E., Marignier, R., Mathey, G., Morel, N., Thouvenot, E., Zéphir, H., … Cohen, M. (2024). Cancer and multiple sclerosis: 2023 recommendations from the French Multiple Sclerosis Society. Multiple Sclerosis (Houndmills, Basingstoke, England), 13524585231223880. notice. https://doi.org/10.1177/13524585231223880
Bernard, M. (2024). Editorial for “Pulmonary Transit Time Derived from First-Pass Perfusion Cardiac MR Imaging: A Potential New Marker for Cardiac Involvement and Prognosis in Light-Chain Amyloidosis.” Journal of Magnetic Resonance Imaging, 60(3), 1011–1012. file. https://doi.org/10.1002/jmri.29136
Kober, F., Caus, T., Riberi, A., Le Fur, Y., & Bernard, M. (2024). Time Course of High-Energy Phosphate Depletion During Cold Storage of Human Heart Grafts Using the Celsior Solution. Transplant International: Official Journal of the European Society for Organ Transplantation, 37, 12994. file. https://doi.org/10.3389/ti.2024.12994
Božić-Iven, M., Rapacchi, S., Tao, Q., Pierce, I., Thornton, G., Nitsche, C., Treibel, T. A., Schad, L. R., & Weingärtner, S. (2024). Improved reproducibility for myocardial ASL: Impact of physiological and acquisition parameters. Magnetic Resonance in Medicine, 91(1), 118–132. file. https://doi.org/10.1002/mrm.29834
Cadour, F., Cour, A., Senlis, J., Rapacchi, S., Chennoufi, H., Michelin, P., McQuade, C., Demeyere, M., & Dacher, J.-N. (2024). How to use MRI in cardiac disease with diastolic dysfunction? The British Journal of Radiology, tqae071. file. https://doi.org/10.1093/bjr/tqae071