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Invited seminar : An Update on Cardiac ASL-MRI and Brain Tumor DCE-MRI

Abstract:

This talk will summarize two of the translational MRI efforts in my lab. One is the application of arterial spin labeling (ASL) to the human heart. ASL is a non-contrast technique for measuring tissue perfusion, and could be extremely valuable in the assessment of ischemic heart disease, especially high-risk groups such as those with kidney failure. Cardiac ASL-MRI is challenging because of the heart’s motion, and complex geometry of the blood supply. The second project is the improvement of dynamic contrast enhanced (DCE) MRI of brain tumors. DCE-MRI is a potentially powerful technique for measuring kinetic parameters, which are important in determining progression of disease and effectiveness of treatments. Our work is focused on the use of sparse sampling and model-constrained reconstruction to produce a more comprehensive and reproducible test.

Bio:

Krishna Nayak is a Professor of Electrical Engineering at the University of Southern California (USC), with joint appointments in Biomedical Engineering and Radiology. His research involves the development and translation of novel magnetic resonance imaging (MRI) acquisition, reconstruction, and analysis techniques. Current projects include applications of real-time MRI, cardiac MRI without contrast agents, and application of sparse sampling and constrained reconstruction to clinical MRI. He received his PhD in Electrical Engineering from Stanford University in 2001, his MS in Electrical Engineering from Stanford in 1996, and BS degrees in Electrical Engineering, Computer Science, and Applied Mathematics from Florida State University in 1995. Dr. Nayak has published 100+ journal papers, 250+ conference papers, and has received 10+ US patents. He is also interested in ultimate frisbee, parenting, scientific and social bias, and STEM engagement.